Patents by Inventor Nicola Pilone

Nicola Pilone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12352379
    Abstract: The present invention relates to a composite coating for an inner tube delimiting a passageway for a fluid for obtaining a pipe for conveying fluids in HVACR systems.
    Type: Grant
    Filed: March 20, 2023
    Date of Patent: July 8, 2025
    Assignee: PTUBES, INC.
    Inventor: Nicola Pilone
  • Publication number: 20250198560
    Abstract: A pipe for conveying fluids in Heating Ventilation Air-Conditioning Refrigeration (HVACR) systems includes an inner tube delimiting a passageway for fluid flow and a tubular insulating cover surrounding the inner tube. The tubular insulating cover includes an insulation material. A tubular jacket surrounds and is bonded to an outer surface of the tubular insulating cover, wherein the tubular jacket includes an extruded thermoplastic elastomer directly extruded onto the tubular insulating cover to form a composite structure.
    Type: Application
    Filed: February 26, 2025
    Publication date: June 19, 2025
    Inventor: Nicola Pilone
  • Patent number: 12241581
    Abstract: The present invention relates to a composite coating for an inner tube delimiting a passageway for a fluid for obtaining a pipe for conveying fluids in HVACR systems. A composite coating according to the present invention includes at least one tubular insulating cover made of an insulation material and designed to cover an inner tube, said insulation material including a mixture of polyvinyl chloride (PVC), nitrile butadiene rubber (NBR), ethylene-propylene-diene-monomer (EPDM) and/or polypropylene (PP) based foam, and further includes at least one tubular jacket coating said tubular insulating cover, which tubular jacket is made of at least one compound selected from the group including thermoplastic elastomer, polyethylene (PE), polyvinyl chloride (PVC) or a mixture of elastomers and polymers.
    Type: Grant
    Filed: August 9, 2021
    Date of Patent: March 4, 2025
    Assignee: Ptubes, Inc.
    Inventor: Nicola Pilone
  • Publication number: 20240366723
    Abstract: The present application relates to a method for treating a human subject suffering from an enteric neuropathy such as Hirschsprung disease (HSCR) or intestinal hypoganglionosis through the administration of an effective dose of a combination comprising a Glial cell line-Derived Neurotrophic Factor (GDNF) polypeptide and a short chain fatty acid such as butyric acid.
    Type: Application
    Filed: June 15, 2022
    Publication date: November 7, 2024
    Inventors: Nicolas PILON, Rodolphe SORET
  • Patent number: 11828404
    Abstract: The present invention relates to a composite coating for an inner tube delimiting a passageway for a fluid for obtaining a pipe for conveying fluids in HVACR systems.
    Type: Grant
    Filed: August 9, 2021
    Date of Patent: November 28, 2023
    Assignee: PTUBES, INC.
    Inventor: Nicola Pilone
  • Publication number: 20230228362
    Abstract: The present invention relates to a composite coating for an inner tube delimiting a passageway for a fluid for obtaining a pipe for conveying fluids in HVACR systems.
    Type: Application
    Filed: March 20, 2023
    Publication date: July 20, 2023
    Inventor: Nicola Pilone
  • Publication number: 20230127097
    Abstract: The present invention relates to a pipe suitable for conveying fluids in HVACR applications, which pipe comprises an inner tube delimiting an inner space or passageway for a fluid, an insulating cover and an anti-corrosion layer.
    Type: Application
    Filed: December 22, 2022
    Publication date: April 27, 2023
    Inventor: Nicola Pilone
  • Patent number: 11566729
    Abstract: The present invention relates to a pipe suitable for conveying fluids in HVACR applications, which pipe comprises an inner tube delimiting an inner space or passageway for a fluid, an insulating cover and an anti-corrosion layer.
    Type: Grant
    Filed: August 9, 2021
    Date of Patent: January 31, 2023
    Assignee: PTUBES, INC.
    Inventor: Nicola Pilone
  • Publication number: 20230022970
    Abstract: The present application relates to a method for inducing neurogenesis in an aganglionic or hypoganglionic segment of the distal colon of a human subject suffering from an enteric neuropathy such as Hirschsprung disease (HSCR) or intestinal hypoganglionosis through the administration of an effective dose of recombinant Glial cell line-Derived Neurotrophic Factor (GDNF) polypeptide into the distal colon of the subject. The method also permits to correct the imbalance of nitrergic and cholinergic neuron subtypes located upstream of the aganglionic or hypoganglionic segment and restore distal colon function (e.g., motility and epithelial barrier) in the subject.
    Type: Application
    Filed: December 18, 2020
    Publication date: January 26, 2023
    Inventors: Rodolphe SORET, Nicolas PILON
  • Publication number: 20210396344
    Abstract: The present invention relates to a composite coating for an inner tube delimiting a passageway for a fluid for obtaining a pipe for conveying fluids in HVACR systems.
    Type: Application
    Filed: August 9, 2021
    Publication date: December 23, 2021
    Inventor: Nicola Pilone
  • Publication number: 20210364121
    Abstract: The present invention relates to a composite coating for an inner tube delimiting a passageway for a fluid for obtaining a pipe for conveying fluids in HVACR systems.
    Type: Application
    Filed: August 9, 2021
    Publication date: November 25, 2021
    Inventor: Nicola Pilone
  • Publication number: 20210364106
    Abstract: The present invention relates to a pipe suitable for conveying fluids in HVACR applications, which pipe comprises an inner tube delimiting an inner space or passageway for a fluid, an insulating cover and an anti-corrosion layer.
    Type: Application
    Filed: August 9, 2021
    Publication date: November 25, 2021
    Inventor: Nicola Pilone
  • Publication number: 20060236415
    Abstract: A vector comprising a promoter sequence driving the coding sequence of a visual marker protein, wherein the promoter sequence functions specifically in neural crest cells and methods for using same.
    Type: Application
    Filed: March 9, 2006
    Publication date: October 19, 2006
    Inventors: David Silversides, Nicolas Pilon, Diana Raiwet, Robert Viger, Eric Legault
  • Publication number: 20040177389
    Abstract: Methods for controlling sex determination in non-human mammals are provided, including constructs for the production of transgenic mammals and the non-human transgenic mammals themselves.
    Type: Application
    Filed: April 12, 2004
    Publication date: September 9, 2004
    Inventors: David William Silversides, Maria Isabelle Daneau, Nicolas Pilon, Saffron C Dornan