Patents by Inventor Nicola Zambrano

Nicola Zambrano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HUMAN NEUTRALIZING ANTIGEN SPECIFIC PROTEINS FOR SPIKE-RBD OF SARS-COV-2
    Publication number: 20240166727
    Abstract: The invention concerns antigen specific proteins, in particular antibodies or fragments thereof, specifically binding to RBD domain and interfering in the interaction of Spike protein with ACE2 receptor, said antigen specific proteins having neutralizing activity for infection of SARS-COV2 virus and its derived variants.
    Type: Application
    Filed: March 21, 2022
    Publication date: May 23, 2024
    Applicant: CEINGE BIOTECNOLOGIE AVANZATE SCARL
    Inventors: Claudia De Lorenzo, Nicola Zambrano, Massimo Zollo
  • ANTAGONISTIC PD-1, PD-L1 AND LAG-3 BINDING PROTEINS
    Publication number: 20200407447
    Abstract: The present invention relates to antagonistic antigen binding proteins, a nucleic acid encoding the antagonistic binding protein, a recombinant expression vector comprising the nucleic acid molecule, a host cell comprising the vector, a method of making the antagonistic antigen binding protein, an antagonistic binding protein produced by the method and a pharmaceutical composition comprising the antagonistic binding protein, the nucleic acid or the vector. The present invention further relates to a kit comprising the pharmaceutical composition and use of the antagonistic binding protein in the treatment of cancer and/or chronic infectious diseases.
    Type: Application
    Filed: March 22, 2019
    Publication date: December 31, 2020
    Inventors: Alfredo NICOSIA, Nicola ZAMBRANO, Emanuele SASSO, Claudia DE LORENZO
  • Inhibitors of Src kinase for use in alzheimer's disease
    Publication number: 20040176313
    Abstract: The present invention relates to the identification of inhibitors of Src kinase, assays and methods useful for such identification and the use of Src inhibitors for the preparation of pharmaceuticals for the treatment of Alzheimer's disease.
    Type: Application
    Filed: October 22, 2003
    Publication date: September 9, 2004
    Applicant: Aventis Pharma S.A.
    Inventors: Luc Mercken, Nicola Zambrano, Tommaso Russo