Patents by Inventor Nicolaas C. M. E. Barendse

Nicolaas C. M. E. Barendse has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of N-(sulfonylmethyl) formamide compounds
    Patent number: 4922016
    Abstract: N-(sulfonylmethyl)formamides are obtained by reacting a sulfinic acid, formaldehyde and formamide in the presence of a second acid and a controlled amount of water. The formamides can be converted to the corresponding sulfonylmethylisocyanides.
    Type: Grant
    Filed: July 26, 1989
    Date of Patent: May 1, 1990
    Assignee: Gist-Brocades N.V.
    Inventor: Nicolaas C. M. E. Barendse
  • Process for the preparation of 9(11)-dehydro steroids
    Patent number: 4917827
    Abstract: 9(11)-dehydroandrostanes and 9(11)-dehydropregnanes are prepared by dehydrating the corresponding 9-alpha-hydroxy steroid in the presence of a Lewis acid. The corresponding 8(9)-dehydro-isomer was not detectable. The resulting products are valuable intermediates in steroid synthesis especially in the preparation of corticosteroids.
    Type: Grant
    Filed: June 10, 1988
    Date of Patent: April 17, 1990
    Assignee: Gist-Brocades N.V.
    Inventors: Jacobus N. M. Batist, Nicolaas C. M. E. Barendse, Arthur F. Marx