Patents by Inventor Nicolaas Cornelis Barendse

Nicolaas Cornelis Barendse has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6369036
    Abstract: The present invention provides a method of preparing an improved antifungal composition containing an antifungal compound of the polyene type such as natamycin wherein the antifungal compound is incorporated into the composition in a form which shows an enhanced activity, e.g. in the form of a solution and/or being in a modified polymorphic form.
    Type: Grant
    Filed: April 30, 1998
    Date of Patent: April 9, 2002
    Assignee: DSM N.V.
    Inventors: Ferdinand Theodorus Van Rijn, Jacobus Stark, Hong Sheng Tan, Willem Johan Van Zoest, Nicolaas Cornelis Barendse
  • Patent number: 5821233
    Abstract: Novel compositions that comprise solvates, salts, or other modified crystalline forms of polyene-type antifungal compounds are provided. Representative of such compositions are formulations that comprise the novel cystalline substances .delta.-natamycin and .gamma.-natamycin. Additionally, there are provided methods of preparing or storing such compositions, and also methods of use whereby an enhanced rate of release of antifungal compound, in a pharmaceutical or food products application is achieved.
    Type: Grant
    Filed: May 26, 1995
    Date of Patent: October 13, 1998
    Assignee: Gist-Brocades, N.V.
    Inventors: Ferdinand Theodorus Van Rijn, Jacobus Stark, Hong Sheng Tan, Willem Johan Van Zoest, Nicolaas Cornelis Barendse