Patents by Inventor Nicolaas Duneas

Nicolaas Duneas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cross-Linked Non-Demineralized Collagenous Biomaterial
    Publication number: 20130101675
    Abstract: A cross-linked non-demineralized collagenous biomaterial and a method for making and using the same to regenerate tissue are described. The collagenous biomaterial is produced by sourcing a raw material of bone powder and tendon which were not subjected to treatment that would demineralize them, extracting the raw material to form a collagenous biomaterial, and irradiating the collagenous biomaterial with gamma radiation. The collagenous biomaterial is administered to a treatment site by an administration apparatus.
    Type: Application
    Filed: September 21, 2012
    Publication date: April 25, 2013
    Inventors: Nicolaas Duneas, Martina Magdel Lutz
  • Method of preparing an osteogenic protein fraction
    Patent number: 7728116
    Abstract: In a method of isolating osteogenic protein from bone, in which an osteogenic protein-containing fraction is extracted from bone and enriched by a sequence of enrichment steps selected from ultrafiltration and chromatography, the invention provides the improvement of removing higher molecular weight components from the osteogenic protein-containing fraction prior to the enrichment steps. The higher molecular weight components have a molecular weight of about 100-300 kDa and are selected from collagen, collagen fragments, collagen aggregates and mixtures thereof.
    Type: Grant
    Filed: June 18, 2003
    Date of Patent: June 1, 2010
    Assignee: Altis Biologics (Proprietary) Limited
    Inventor: Nicolaas Duneas
  • Cross-linked collagenous biomaterial
    Publication number: 20070082059
    Abstract: A method or producing a cross-linked collagenous biomaterial includes the step of providing a collagenous biomaterial and irradiating the collagenous biomaterial with gamma radiation at a dose of between about 20 and 160 kGy to produce the cross-linked collagenous biomaterial. The collagenous biomaterial is provided in the form of a gel and is produced by extracting bone powder or tendon.
    Type: Application
    Filed: October 17, 2006
    Publication date: April 12, 2007
    Inventors: Nicolaas Duneas, Martina Lutz
  • Osteoinductive biomaterials
    Publication number: 20060093640
    Abstract: In a method of isolating osteogenic protein from bone, in which an osteogenic protein-containing fraction is extracted from bone and enriched by a sequence of enrichment steps selected from ultrafiltration and chromatography, the invention provides the improvement of removing higher molecular weight components from the osteogenic protein-containing fraction prior to the enrichment steps. The higher molecular weight components have a molecular weight of about 100-300 kDa and are selected from collagen, collagen fragments, collagen aggregates and mixtures thereof.
    Type: Application
    Filed: June 18, 2003
    Publication date: May 4, 2006
    Inventor: Nicolaas Duneas
  • Biocidal composition
    Patent number: 7030163
    Abstract: A biocidal composition includes, in combination, poly(hexamethylene)biguanide, didecyldimethylammonium chloride a homogenizing agent and a flocculating agent. The biocidal composition is used to treat water to control microorganisms.
    Type: Grant
    Filed: February 15, 2002
    Date of Patent: April 18, 2006
    Assignee: Ipsilon Laboratories CC
    Inventor: Nicolaas Duneas
  • Cross-linked collagenous biomaterial
    Publication number: 20050152986
    Abstract: A method or producing a cross-linked collagenous biomaterial includes the step of providing a collagenous biomaterial and irradiating the collagenous biomaterial with gamma radiation at a dose of between about 20 and 160 kGy to produce the cross-linked collagenous biomaterial. The collagenous biomaterial is provided in the form of a gel and is produced by extracting bone powder or tendon.
    Type: Application
    Filed: September 4, 2002
    Publication date: July 14, 2005
    Inventors: Nicolaas Duneas, Martina Lutz
  • Biocidal composition and a method of treating water
    Publication number: 20040154999
    Abstract: A biocidal compsition includes, in combination, poly(texamethylene) biguanide, didecydimethylammonium chloride a homogenising agent and a flocculating agent. The biocidal composition is used to treat water to control microorganisms.
    Type: Application
    Filed: February 15, 2002
    Publication date: August 12, 2004
    Inventor: Nicolaas Duneas