Patents by Inventor Nicolaas Frans de Rooij

Nicolaas Frans de Rooij has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6405934
    Abstract: The liquid droplet spray device (1) comprises a housing formed of a superposition of a first and a second substrate (5, 6) and a space (2) within the housing for containing a liquid substance (3), vibrating means (8) for applying a frequency vibration to the substance (3) thereby generating the liquid droplet spray, and outlet means (7, 9, 10) for ejecting the liquid droplet spray. The outlet means comprise a cavity (7), output nozzles (9) and output channels (10) connecting the cavity (7) to the outlet nozzles (9). According to the invention, the vibrating means (8) creates a standing wave pattern within the liquid substance (3), and the outlet means are arranged such that said outlet nozzles (9) are superposed on the vibration mode peaks of the standing wave pattern. Advantageously, the first and second substrates have similar geometrical shapes. Minimal retention and optimal flow of the substance are obtained.
    Type: Grant
    Filed: November 17, 1999
    Date of Patent: June 18, 2002
    Assignee: Microflow Engineering SA
    Inventors: Joseph Hess, Hu Bo, Raphael Weber, Isabel Ortega, Cedric Barraud, Nicolaas Frans de Rooij, Bas de Heij
  • Patent number: 6196219
    Abstract: The liquid droplet spray device (5) has a micromachined substrate (8, 18, 18a; 8a, 18, 18a), a space (9) within the substrate for containing a liquid substance (4), an inlet channel for supplying (7) the liquid (4) to the space (9), and outlet structure (13, 14, 15) for ejecting the liquid as a mono-dispersive droplet spray when the liquid undergoes a vibration. The outlet structure comprises a cut-off pyramid-shaped tapered cavity (13) which is micromachined in the space (9). The outlet structure further comprises at least one output (14) and output channel (15) connecting the tapered cavity (13) to the outlet (14), the outlet (14) and the output channel (15) having a non-tapered vertical shape. Thanks to such a device, the exact amount ejected may be determined accurately which allows for a predicted lung deposition of the droplets by using appropriate control means adapted to the kind of patient.
    Type: Grant
    Filed: November 19, 1998
    Date of Patent: March 6, 2001
    Assignee: Microflow Engineering SA
    Inventors: Joseph Hess, Hu Bo, Raphaël Weber, Isabel Ortega, Cédric Barraud, Bart van der Schoot, Nicolaas Frans de Rooij, Bas de Heij
  • Patent number: 5462839
    Abstract: This process consists of machining a silicon piece (4) by means of selective oxidation operations and photolithography to form therein at least one cavity (7, 12) adapted to contain or convey a fluid, and of oxidizing the wall of the cavity to make this hydrophilic. The device is completed by fixing closing plates (1, 5) to its body thus formed. Prior to the machining operations the surfaces of the piece (4) adapted to be in contact with the closing plates (1, 5) are covered with a screening layer that resists these machining operations. Then, after these have been completed, the surfaces of the piece intended to be exposed to the fluid are oxidized to form therein an oxide layer favoring the wettability of these surfaces. The screening layer is then removed and the closing plates are fixed to the piece.The invention has applications, notably in micropumps.
    Type: Grant
    Filed: May 23, 1994
    Date of Patent: October 31, 1995
    Assignee: Universite de Neuchatel
    Inventors: Nicolaas Frans de Rooij, Sylvain Jeanneret, Volker Gass, Bart van der Schoot