Patents by Inventor Nicolai V. Kaverin

Nicolai V. Kaverin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Influenza virus replicated in mammalian cell culture and vaccine production
    Patent number: 6344354
    Abstract: The invention provides replication of high growth influenza virus strains, derived from clinical isolates, in cultured mammalian cells by infecting the mammalian cells with the high growth strains to obtain infected cells, and culturing the cells while maintaining a trypsin concentration range of 0.05-1.0 &mgr;g/ml in the culture medium, where the resulting replicated virus is suitable for use in mammalian influenza vaccines and vaccination methods, which are also provided by the invention.
    Type: Grant
    Filed: June 16, 1998
    Date of Patent: February 5, 2002
    Assignee: St. Jude Children's Research Hospital
    Inventors: Robert G. Webster, Nicolai V. Kaverin
  • Influenza virus replicated in mammalian cell culture and vaccine production
    Patent number: 5824536
    Abstract: The invention provides replication of high growth influenza virus strains, derived from clinical isolates, in cultured mammalian cells by infecting the mammalian cells with the high growth strains to obtain infected cells, and culturing the cells while maintaining a trypsin concentration range of 0.05-1.0 .mu.g/ml in the culture medium, where the resulting replicated virus is suitable for use in mammalian influenza vaccines and vaccination methods, which are also provided by the invention.
    Type: Grant
    Filed: June 17, 1996
    Date of Patent: October 20, 1998
    Assignee: St. Jude Children's Research Hospital
    Inventors: Robert G. Webster, Nicolai V. Kaverin