Patents by Inventor Nicolaos Christodoulides

Nicolaos Christodoulides has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bio-nano-chips for on-site drug screening
    Patent number: 9709580
    Abstract: A bio-nano-chip (BNC) technology that works in connection with non-invasive samples, such as saliva, cheek swab or urine samples that can be easily performed by non-specialists, such as security personnel and police officers is disclosed. The microfluidic system for drug testing includes an analyzer or reader having a housing containing a slot for receiving a cartridge, a drug testing cartridge, a processor having a user interface, an optical or energy sensing means, and a means for moving fluid.
    Type: Grant
    Filed: March 21, 2012
    Date of Patent: July 18, 2017
    Assignee: William Marsh Rice University
    Inventors: John T. McDevitt, Nicolaos Christodoulides, Pierre N. Floriano, Glennon Simmons
  • Prostate cancer point of care diagnostics
    Patent number: 9671413
    Abstract: The invention relates to point of care diagnostic disposables, devices, methods, and systems for diagnosing or predicting prostate cancer. The present invention employs biomarker specific reagents in disposable cassettes or lab cards for use as analyzers, as well as software to evaluate and report test results. The system promises to improve point of care in vitro diagnostics.
    Type: Grant
    Filed: November 11, 2011
    Date of Patent: June 6, 2017
    Assignees: William Marsh Rice University, Board of Regents of the University of Texas System
    Inventors: John T. McDevitt, Nicolaos Christodoulides, Pierre N. Floriano, Ian Thompson
  • Oral cancer point of care diagnostics
    Patent number: 9535068
    Abstract: A point of care diagnostic test, device and disposables for determining a patient risk for oral cancer in the same visit that a sample is collected.
    Type: Grant
    Filed: November 11, 2011
    Date of Patent: January 3, 2017
    Assignee: William Marsh Rice University
    Inventors: John T. McDevitt, Nicolaos Christodoulides, Pierre N. Floriano, Martin Thornhill, Spencer Redding, Nadarajah Vigneswaran, Craig Murdoch, Paul Speight
  • BIO-NANO-CHIP FOR ANTICONVULSANT DRUG SALIVARY ASSAY
    Publication number: 20150111778
    Abstract: This disclosure describes portable bio-nano-chip (BNC) assays of antiepileptic drugs (AED) using salivary samples. The BNC technology results in a more convenient, less expensive, and less time consuming sampling and analysis.
    Type: Application
    Filed: October 1, 2014
    Publication date: April 23, 2015
    Inventors: John T. MCDEVITT, Nicolaos CHRISTODOULIDES, Giridhar P. KALAMANGALAM
  • BIO-NANO-CHIPS FOR ON-SITE DRUG SCREENING
    Publication number: 20140094391
    Abstract: A bio-nano-chip (BNC) technology that works in connection with non-invasive samples, such as saliva, cheek swab or urine samples that can be easily performed by non-specialists, such as security personnel and police officers is disclosed. The microfluidic system for drug testing includes an analyzer or reader having a housing containing a slot for receiving a cartridge, a drug testing cartridge, a processor having a user interface, an optical or energy sensing means, and a means for moving fluid.
    Type: Application
    Filed: March 21, 2012
    Publication date: April 3, 2014
    Applicant: WILLIAM MARSH RICE UNIVERSITY
    Inventors: John T. McDevitt, Nicolaos Christodoulides, Pierre N. Floriano, Glennon Simmons
  • ORAL CANCER POINT OF CARE DIAGNOSTICS
    Publication number: 20130295580
    Abstract: A point of care diagnostic test, device and disposables for determining a patient risk for oral cancer in the same visit that a sample is collected.
    Type: Application
    Filed: November 11, 2011
    Publication date: November 7, 2013
    Applicants: William Marsh Rice University, University of Sheffield, The Board of Regents of the University of Texas System
    Inventors: John T. McDevitt, Nicolaos Christodoulides, Pierre N. Floriano, Martin Thornhill, Spencer Redding, Nadarajah Vigneswaran, Craig Murdoch, Paul Speight
  • PROSTATE CANCER POINT OF CARE DIAGNOSTICS
    Publication number: 20130274136
    Abstract: The invention relates to point of care diagnostic disposables, devices, methods, and systems for diagnosing or predicting prostate cancer. The present invention employs biomarker specific reagents in disposable cassettes or lab cards for use as analyzers, as well as software to evaluate and report test results. The system promises to improve point of care in vitro diagnostics.
    Type: Application
    Filed: November 11, 2011
    Publication date: October 17, 2013
    Applicants: UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER, WILLIAM MARSH RICE UNIVERSITY
    Inventors: John T. McDevitt, Nicolaos Christodoulides, Pierre N. Floriano, Ian Thompson
  • BRAIN INJURY BIOMARKER PANEL
    Publication number: 20120322682
    Abstract: A panel of biomarkers for diagnosis, monitoring of progression and prognosis of various brain injuries and PTSD.
    Type: Application
    Filed: June 19, 2012
    Publication date: December 20, 2012
    Applicant: WILLIAM MARSH RICE UNIVERSITY
    Inventors: John MCDEVITT, Nicolaos CHRISTODOULIDES, Pierre N. FLORIANO
  • METHODS AND COMPOSITIONS FOR DIAGNOSIS OF ACUTE MYOCARDIAL INFARCTION (AMI)
    Publication number: 20120208715
    Abstract: Embodiments of the invention utilizes advanced detection methodologies, such as the lab-on-a-chip (LOC) technology, as a cost-effective, efficient, ultra-sensitive rapid method for diagnosing Acute Myocardial Infarction (AMI) in human subjects. In certain aspects, multiple biomarkers of AMI are concurrently detected and measured in serum and saliva to provide a more efficient, sensitive and accurate diagnosis of AMI.
    Type: Application
    Filed: August 20, 2010
    Publication date: August 16, 2012
    Inventors: John T. McDevitt, Craig S. Miller, Jeffrey L. Ebersole, Nicolaos Christodoulides, Pierre N. Floriano
  • CARDIBIOINDEX/CARDIBIOSCORE AND UTILITY OF SALIVARY PROTEOME IN CARDIOVASCULAR DIAGNOSTICS
    Publication number: 20080300798
    Abstract: Embodiments of the invention include methods by which cardiac biomarkers are assigned an index (cardiovascular biomarker index-cardiobioindex, CBI) as a means to describe the utility of each biomarker, or combination of biomarkers for risk evaluation, diagnosis or prognosis of cardiovascular disease status.
    Type: Application
    Filed: April 16, 2008
    Publication date: December 4, 2008
    Inventors: John T. McDevitt, Nicolaos Christodoulides, Pierre N. Floriano, Craig S. Miller, Jeffrey L. Ebersole
  • DETECTING HUMAN OR ANIMAL IMMUNOGLOBIN-E
    Publication number: 20080176253
    Abstract: Methods, systems, and apparatus for detecting the presence of human or animal immunoglobin-E are described. A fluid or gas sample may pass through a particle-based detection system of a cartridge. Detection and analysis techniques may be applied to determine the identity and quantity of the captured IgE.
    Type: Application
    Filed: May 10, 2007
    Publication date: July 24, 2008
    Inventors: Nicolaos Christodoulides, Pierre N. Floriano, Karri Ballard, John T. McDevitt
  • DETECTING MULTIPLE TYPES OF LEUKOCYTES
    Publication number: 20080050830
    Abstract: Methods, systems, and apparatus for detecting multiple types of leukocytes in a blood sample material. A fluid or gas sample may pass through a sieve-based detection system of a cartridge. Detection and analysis techniques may be applied to determine the relative distribution of multiple types of white blood cells in the sample.
    Type: Application
    Filed: May 10, 2007
    Publication date: February 28, 2008
    Inventors: Pierre Floriano, Nicolaos Christodoulides, Karri Ballard, John McDevitt
  • DETECTING TUMOR BIOMARKER IN ORAL CANCER
    Publication number: 20080038738
    Abstract: Methods and device for detecting the presence of tumor biomarkers in oral squamous cell carcinoma.
    Type: Application
    Filed: May 10, 2007
    Publication date: February 14, 2008
    Inventors: Shannon Weigum, Pierre Floriano, Nicolaos Christodoulides, John McDevitt