Patents by Inventor Nicolas Barnich

Nicolas Barnich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GLYCOSIDE INHIBITORS OF YEAST
    Publication number: 20240148778
    Abstract: A composition of yeast polysaccharides including ?(1,6)-glucans, preferably also mannans and ?-glucans. The yeast polysaccharides are extracted from yeast cell wall fragments. Typically, the ?-glucans are ?(1,6)-glucans. Also, a method for obtaining such a composition, including at least one step of fractionating a composition of yeast cell walls and extracting an insoluble fraction, and at least one step of extracting a soluble fraction from the insoluble fraction obtained in step a). Further, a composition with a human or veterinary therapeutic objective, for the treatment of gastrointestinal pathologies associated with pathogenic microorganisms, as well as to its non-therapeutic use for improving intestinal comfort.
    Type: Application
    Filed: March 15, 2022
    Publication date: May 9, 2024
    Applicants: LESAFFRE ET COMPAGNIE, UNIVERSITÉ CLERMONT AUVERGNE, UNIVERSITE DE LILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS
    Inventors: Nathalie BALLET, Pascal VANDEKERCKOVE, Yann GUERARDEL, Shin-Yi YU, Adeline SIVIGNON, Nicolas BARNICH
  • Mannose derivatives useful for treating pathologies associated with adherent
    Patent number: 10543223
    Abstract: The present invention relates to mannose derivatives of formula (I): wherein R1 represents H, CO—(C1-C6)-alkyl or CO-alkylaryl, Y represents a single bond, CH2, O, NR3, S, A represents O, NH or S, X represents H and X? represents OH or X and X? taken together with the carbon atom bearing them form a CO group, R2 represents H, a linear or branched (C1-C6)-alkyl or CF3, R3 represents H, a C1-C6 alkyl, a CO—(C1-C6)-alkyl, CF3 or COCF3, and R is as described in claim 1.
    Type: Grant
    Filed: August 5, 2016
    Date of Patent: January 28, 2020
    Assignees: ENTEROME, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE CLERMONT AUVERGNE, UNIVERSITE DE NANTES
    Inventors: Sebastien Gouin, Thibault Chalopin, Julie Bouckaert, Nicolas Barnich, Adeline Sivignon, Dimitri Alexander Alvarez-Dorta, Francois Bellamy
  • MANNOSE DERIVATIVES USEFUL FOR TREATING PATHOLOGIES ASSOCIATED WITH ADHERENT E. COLI
    Publication number: 20180235991
    Abstract: The present invention relates to mannose derivatives of formula (I): wherein R1 represents H, CO—(C1-C6)-alkyl or CO-alkylaryl, Y represents a single bond, CH2, O, NR3, S, A represents O, NH or S, X represents H and X? represents OH or X and X? taken together with the carbon atom bearing them form a CO group, R2 represents H, a linear or branched (C1-C6)-alkyl or CF3, R3 represents H, a C1-C6 alkyl, a CO—(C1-C6)-alkyl, CF3 or COCF3, and R is as described in claim 1.
    Type: Application
    Filed: August 5, 2016
    Publication date: August 23, 2018
    Inventors: Sebastien GOUIN, Thibault CHALOPIN, Julie BOUCKAERT, Nicolas BARNICH, Adeline SIVIGNON, Dimitri Alexander ALVAREZ-DORTA, Francois BELLAMY
  • METHOD FOR DIAGNOSING AND TREATING CROHN'S DISEASE
    Publication number: 20160091501
    Abstract: The present invention relates to an in vitro method for diagnosing Crohn's disease or for determining predisposition in a person to develop Crohn's disease, by detecting an overexpression of the CD66c receptor in subjects suffering from said disease or at risk of developing the disease. The invention also relates to preventive or curative treatment for Crohn's disease.
    Type: Application
    Filed: September 30, 2015
    Publication date: March 31, 2016
    Inventors: Nicolas BARNICH, Arlette Darfeuille-Michaud, Anne-Lise Glasser
  • Method for diagnosing and treating Crohn's disease
    Patent number: 9176131
    Abstract: The invention concerns an in vitro method for diagnosing Crohn's disease, or for determining predisposition in a person to develop Crohn's disease, by detecting an overexpression of the CD66c receptor in subjects suffering from said disease or at risk. The invention also concerns preventive or curative treatment of Crohn's disease.
    Type: Grant
    Filed: October 13, 2005
    Date of Patent: November 3, 2015
    Assignee: LESAFFRE ET COMPAGNIE
    Inventors: Nicolas Barnich, Arlette Darfeuille-Michaud, Anne-Lise Glasser
  • METHOD FOR DIAGNOSING AND TREATING CROHN'S DISEASE
    Publication number: 20100015600
    Abstract: The invention concerns an in vitro method for diagnosing Crohn's disease, or for determining predisposition in a person to develop Crohn's disease, by detecting an overexpression of the CD66c receptor in subjects suffering from said disease or at risk. The invention also concerns preventive or curative treatment of Crohn's disease.
    Type: Application
    Filed: October 13, 2005
    Publication date: January 21, 2010
    Inventors: Nicolas Barnich, Arlette Darfeuille-Michaud, Anne-Lise Glasser