Patents by Inventor Nicolas Bernthal

Nicolas Bernthal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multi-arm block-copolymers for multifunctional self-assembled systems
    Patent number: 12208178
    Abstract: A copolymer poly(ethylene glycol)-polyallyl mercaptan (PEG-PAM) material is used as a drug-containing coating for medical implants. In one embodiment, a mixture of multi-arm poly(ethylene glycol) (PEG), polyallyl mercaptan (PAM), a photoinitiator, organic solvent, and one or more drugs, medicaments, or pharmaceutical compounds is applied to a surface of the implant and is exposed to a polymerizing light source to form a PEG-PAM material coating that is formed in situ on the implant. The PEG-PAM coating may be used by surgeons to incorporate antibacterial drugs or the like into coatings that are applied in the operating room setting to medical devices such as orthopedic implants. The type of drug and dosing can be customized during the coating operation and tailored to the patient's needs. PEG-PAM may also be applied as a coating on or within tissue or an injectable gel.
    Type: Grant
    Filed: January 30, 2018
    Date of Patent: January 28, 2025
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Tatiana Segura, Nicolas Bernthal, Weixian Xi
  • MULTI-ARM BLOCK-COPOLYMERS FOR MULTIFUNCTIONAL SELF-ASSEMBLED SYSTEMS
    Publication number: 20190388583
    Abstract: A copolymer poly(ethylene glycol)-polyallyl mercaptan (PEG-PAM) material is used as a drug-containing coating for medical implants. In one embodiment, a mixture of multi-arm poly(ethylene glycol) (PEG), polyallyl mercaptan (PAM), a photoinitiator, organic solvent, and one or more drugs, medicaments, or pharmaceutical compounds is applied to a surface of the implant and is exposed to a polymerizing light source to form a PEG-PAM material coating that is formed in situ on the implant. The PEG-PAM coating may be used by surgeons to incorporate antibacterial drugs or the like into coatings that are applied in the operating room setting to medical devices such as orthopedic implants. The type of drug and dosing can be customized during the coating operation and tailored to the patient's needs. PEG-PAM may also be applied as a coating on or within tissue or an injectable gel.
    Type: Application
    Filed: January 30, 2018
    Publication date: December 26, 2019
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Tatiana Segura, Nicolas Bernthal, Weixian Xi