Patents by Inventor Nicolas Bloch

Nicolas Bloch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11883246
    Abstract: The inventions provided herein relate to tissue markers and uses thereof, e.g., to mark a target tissue site (e.g., a biopsy site in a breast tissue) or to produce a cell scaffold. The tissue markers described herein are designed to be resistant to fast migration (e.g., immediate migration after implantation through a needle track) and slow migration (e.g., over an extended period of time) upon implantation at a target tissue site (e.g., a biopsy site in a breast tissue), without using an adhesive. Additionally or alternatively, the tissue markers described herein can be readily detectable by at least one imaging modality, e.g., but not limited to magnetic resonance imaging, X-ray imaging, ultrasound imaging, or a combination thereof.
    Type: Grant
    Filed: November 21, 2013
    Date of Patent: January 30, 2024
    Assignees: TRUSTEES OF BOSTON UNIVERSITY, BOSTON MEDICAL CENTER CORPORATION
    Inventors: Mark W. Grinstaff, Boris Nicolas Bloch, Jonah Kaplan
  • Publication number: 20210121263
    Abstract: The inventions provided herein relate to tissue markers and uses thereof, e.g., to mark a target tissue site (e.g., a biopsy site in a breast tissue) or to produce a cell scaffold. The tissue markers described herein are designed to be resistant to fast migration (e.g., immediate migration after implantation through a needle track) and slow migration (e.g., over an extended period of time) upon implantation at a target tissue site (e.g., a biopsy site in a breast tissue), without using an adhesive. Additionally or alternatively, the tissue markers described herein can be readily detectable by at least one imaging modality, e.g., but not limited to magnetic resonance imaging, X-ray imaging, ultrasound imaging, or a combination thereof.
    Type: Application
    Filed: December 14, 2020
    Publication date: April 29, 2021
    Applicants: TRUSTEES OF BOSTON UNIVERSITY, BOSTON MEDICAL CENTER CORPORATION
    Inventors: Mark W. GRINSTAFF, Boris Nicolas BLOCH, Jonah KAPLAN
  • Publication number: 20180353739
    Abstract: The inventions provided herein relate to injection applicators, tissue markers and uses thereof, e.g., to mark a target tissue site (e.g., a biopsy site in a breast tissue) or to produce a cell scaffold. The tissue markers described herein are designed to be resistant to fast migration (e.g., immediate migration after implantation through a needle track) and slow migration (e.g., over an extended period of time) upon implantation at a target tissue site (e.g., a biopsy site in a breast tissue), without using an adhesive. Additionally or alternatively, the tissue markers described herein can be readily detectable by at least one imaging modality, e.g., but not limited to magnetic resonance imaging, X-ray imaging, ultrasound imaging, or a combination thereof.
    Type: Application
    Filed: August 22, 2018
    Publication date: December 13, 2018
    Applicants: TRUSTEES OF BOSTON UNIVERSITY, BOSTON MEDICAL CENTER CORPORATION
    Inventors: Mark W. GRINSTAFF, Boris Nicolas BLOCH, Jonah KAPLAN
  • Publication number: 20180353738
    Abstract: The inventions provided herein relate to tissue markers and uses thereof, e.g., to mark a target tissue site (e.g., a biopsy site in a breast tissue) or to produce a cell scaffold. The tissue markers described herein are designed to be resistant to fast migration (e.g., immediate migration after implantation through a needle track) and slow migration (e.g., over an extended period of time) upon implantation at a target tissue site (e.g., a biopsy site in a breast tissue), without using an adhesive. Additionally or alternatively, the tissue markers described herein can be readily detectable by at least one imaging modality, e.g., but not limited to magnetic resonance imaging, X-ray imaging, ultrasound imaging, or a combination thereof.
    Type: Application
    Filed: August 22, 2018
    Publication date: December 13, 2018
    Applicants: TRUSTEES OF BOSTON UNIVERSITY, BOSTON MEDICAL CENTER CORPORATION
    Inventors: Mark W. GRINSTAFF, Boris Nicolas BLOCH, Jonah KAPLAN
  • Publication number: 20150297316
    Abstract: The inventions provided herein relate to tissue markers and uses thereof, e.g., to mark a target tissue site (e.g., a biopsy site in a breast tissue) or to produce a cell scaffold. The tissue markers described herein are designed to be resistant to fast migration (e.g., immediate migration after implantation through a needle track) and slow migration (e.g., over an extended period of time) upon implantation at a target tissue site (e.g., a biopsy site in a breast tissue), without using an adhesive. Additionally or alternatively, the tissue markers described herein can be readily detectable by at least one imaging modality, e.g., but not limited to magnetic resonance imaging, X-ray imaging, ultrasound imaging, or a combination thereof.
    Type: Application
    Filed: November 21, 2013
    Publication date: October 22, 2015
    Inventors: Mark W. GRINSTAFF, Boris Nicolas BLOCH, Jonah KAPLAN
  • Publication number: 20100294885
    Abstract: The invention relates to a storage box (13) in which is received a protective mask (4) adapted to be applied on the face of an aircraft crewmember, said storage box further comprising signaling means (19) activable upon occurrence in the aircraft of a triggering event to help said aircraft crewmember distinguish said storage box from its environment.
    Type: Application
    Filed: August 10, 2006
    Publication date: November 25, 2010
    Inventors: Nicolas Bloch, Henri Marotte
  • Publication number: 20090301489
    Abstract: The invention relates to a respiratory gas supply circuit (1) for an aircraft carrying passengers and crewmembers (30), comprising a source of breathable gas (R1, R2), at least one supply line (2) connected to said pressurized source, a regulating device (12) provided on said supply line for controlling the supply of breathable gas, a mixing device (9) provided on said supply line, said mixing device further comprising an ambient air inlet (10) for mixing said ambient air with said breathable gas to provide to at least one passenger or crewmember a respiratory gas corresponding to a mixture of said breathable gas and ambient air, wherein said regulating device is driven by a control signal (FIO2R) function at least of the arterial blood oxygen saturation (SaO2) measured on said at least one passenger or crewmember.
    Type: Application
    Filed: July 12, 2006
    Publication date: December 10, 2009
    Inventors: Nicolas Bloch, Henri Marotte
  • Patent number: 7082946
    Abstract: In order to protect the passengers of an airplane against the effects of depressurization of the cabin, breathing masks are fed with oxygen at a rate which is an increasing function of cabin altitude. Oxygen is fed via a constriction and an economizer bag, and an initial fraction only of the gases breathed out is caused to be re-breathed by collecting the initial fraction in a flexible re-breathing bag in communication with the mask. The re-breathing bag has a volume in inflated state which is not less than the total dead volume of the respiratory tract and the mask. A protective apparatus comprises a feed control unit supplying an adjustable flow rate to masks connected to a general pipe via respective economizer bags. A re-breathing bag retards re-breathing and stores only an initial fraction of the gases breathed out on each exhalation.
    Type: Grant
    Filed: October 31, 2002
    Date of Patent: August 1, 2006
    Assignee: Intertechnique
    Inventors: Eric Farin, Michel Bardel, Nicolas Bloch
  • Patent number: 6966317
    Abstract: Individual respiratory gas supply device comprising a respiratory mask and a facial respirator of the cannula or respiratory flexible oro-nasal shell type for comfortably supplying a subject with respiratory gas during a high-altitude flight. The respiratory mask and the facial respirator are adapted so that in the event of de-pressurization or the presence of toxic gases, the subject equips himself with the respiratory mask possibly after having previously removed the facial respirator. Switching means make it possible to cut off the oxygen supply of the facial respirator and dispense oxygen to the regulator when the subject is equipped with the respiratory mask.
    Type: Grant
    Filed: July 8, 2003
    Date of Patent: November 22, 2005
    Assignee: Intertechnique
    Inventors: Michel Bardel, Nicolas Bloch, Patrice Martinez
  • Publication number: 20040099265
    Abstract: Individual respiratory gas supply device comprising a respiratory mask and a facial respirator of the cannula or respiratory flexible oro-nasal shell type for comfortably supplying a subject with respiratory gas during a high-altitude flight. The respiratory mask and the facial respirator are adapted so that in the event of de-pressurization or the presence of toxic gases, the subject equips himself with the respiratory mask possibly after having previously removed the facial respirator. Switching means make it possible to cut off the oxygen supply of the facial respirator and dispense oxygen to the regulator when the subject is equipped with the respiratory mask.
    Type: Application
    Filed: July 8, 2003
    Publication date: May 27, 2004
    Inventors: Michel Bardel, Nicolas Bloch, Patrice Martinez
  • Publication number: 20030101997
    Abstract: In order to protect the passengers of an airplane against the effects of depressurization of the cabin, breathing masks are fed with oxygen at a rate which is an increasing function of cabin altitude. Oxygen is fed via a constriction and an economizer bag, and an initial fraction only of the gases breathed out is caused to be re-breathed by collecting the initial fraction in a flexible re-breathing bag in communication with the mask. The re-breathing bag has a volume in inflated state which is not less than the total dead volume of the respiratory tract and the mask. A protective apparatus comprises a feed control unit supplying an adjustable flow rate to masks connected to a general pipe via respective economizer bags. A re-breathing bag retards re-breathing and stores only an initial fraction of the gases breathed out on each exhalation.
    Type: Application
    Filed: October 31, 2002
    Publication date: June 5, 2003
    Inventors: Eric Farin, Michel Bardel, Nicolas Bloch
  • Patent number: 5636626
    Abstract: A sealed receptacle (1) contains the additive in liquid phase. A dip tube (3) permits sending the additive to a heating enclosure (5) in which the liquid vaporizes before being sent to a collector-mixer (11) through a constriction (10). The flow rate of additive is controlled by the pressure prevailing above the liquid in the receptacle (1) thanks to a control valve (20) connected by a pressure regulator (25) to a computer (26). This latter receives predetermined values of concentration of the mixture through an input (27). It is preferably connected to a detector (28) of the temperature of the enclosure and/or to an analyzer (30) of the composition of the mixture. Used particularly in anesthesia apparatus.
    Type: Grant
    Filed: November 20, 1995
    Date of Patent: June 10, 1997
    Assignee: Taema
    Inventors: Nicolas Bloch, Stephane Ruton
  • Patent number: 5549105
    Abstract: A subassembly constituted by a body and a cover (2), defines internally gas conduit portions (I.sub.i) delimited by partitions of the body coacting with sealing strips (12) in grooves (11) of the cover (2) and formed and mounted in these grooves by injection molding. The sealing strips (12) are recessed within the grooves (11) and coact with the ends of the partitions of the body extending partially into the grooves (11). For use particularly in anesthetic apparatus.
    Type: Grant
    Filed: September 9, 1994
    Date of Patent: August 27, 1996
    Assignee: L'air Liquide, Societe Anonyme pour l'Etude et l'Exploitation des Procedes Georges Claude
    Inventors: Nicolas Bloch, Yvon Guyomard, Michel Jounenc