Patents by Inventor Nicolas Bloch
Nicolas Bloch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11883246Abstract: The inventions provided herein relate to tissue markers and uses thereof, e.g., to mark a target tissue site (e.g., a biopsy site in a breast tissue) or to produce a cell scaffold. The tissue markers described herein are designed to be resistant to fast migration (e.g., immediate migration after implantation through a needle track) and slow migration (e.g., over an extended period of time) upon implantation at a target tissue site (e.g., a biopsy site in a breast tissue), without using an adhesive. Additionally or alternatively, the tissue markers described herein can be readily detectable by at least one imaging modality, e.g., but not limited to magnetic resonance imaging, X-ray imaging, ultrasound imaging, or a combination thereof.Type: GrantFiled: November 21, 2013Date of Patent: January 30, 2024Assignees: TRUSTEES OF BOSTON UNIVERSITY, BOSTON MEDICAL CENTER CORPORATIONInventors: Mark W. Grinstaff, Boris Nicolas Bloch, Jonah Kaplan
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Publication number: 20210121263Abstract: The inventions provided herein relate to tissue markers and uses thereof, e.g., to mark a target tissue site (e.g., a biopsy site in a breast tissue) or to produce a cell scaffold. The tissue markers described herein are designed to be resistant to fast migration (e.g., immediate migration after implantation through a needle track) and slow migration (e.g., over an extended period of time) upon implantation at a target tissue site (e.g., a biopsy site in a breast tissue), without using an adhesive. Additionally or alternatively, the tissue markers described herein can be readily detectable by at least one imaging modality, e.g., but not limited to magnetic resonance imaging, X-ray imaging, ultrasound imaging, or a combination thereof.Type: ApplicationFiled: December 14, 2020Publication date: April 29, 2021Applicants: TRUSTEES OF BOSTON UNIVERSITY, BOSTON MEDICAL CENTER CORPORATIONInventors: Mark W. GRINSTAFF, Boris Nicolas BLOCH, Jonah KAPLAN
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Publication number: 20180353739Abstract: The inventions provided herein relate to injection applicators, tissue markers and uses thereof, e.g., to mark a target tissue site (e.g., a biopsy site in a breast tissue) or to produce a cell scaffold. The tissue markers described herein are designed to be resistant to fast migration (e.g., immediate migration after implantation through a needle track) and slow migration (e.g., over an extended period of time) upon implantation at a target tissue site (e.g., a biopsy site in a breast tissue), without using an adhesive. Additionally or alternatively, the tissue markers described herein can be readily detectable by at least one imaging modality, e.g., but not limited to magnetic resonance imaging, X-ray imaging, ultrasound imaging, or a combination thereof.Type: ApplicationFiled: August 22, 2018Publication date: December 13, 2018Applicants: TRUSTEES OF BOSTON UNIVERSITY, BOSTON MEDICAL CENTER CORPORATIONInventors: Mark W. GRINSTAFF, Boris Nicolas BLOCH, Jonah KAPLAN
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Publication number: 20180353738Abstract: The inventions provided herein relate to tissue markers and uses thereof, e.g., to mark a target tissue site (e.g., a biopsy site in a breast tissue) or to produce a cell scaffold. The tissue markers described herein are designed to be resistant to fast migration (e.g., immediate migration after implantation through a needle track) and slow migration (e.g., over an extended period of time) upon implantation at a target tissue site (e.g., a biopsy site in a breast tissue), without using an adhesive. Additionally or alternatively, the tissue markers described herein can be readily detectable by at least one imaging modality, e.g., but not limited to magnetic resonance imaging, X-ray imaging, ultrasound imaging, or a combination thereof.Type: ApplicationFiled: August 22, 2018Publication date: December 13, 2018Applicants: TRUSTEES OF BOSTON UNIVERSITY, BOSTON MEDICAL CENTER CORPORATIONInventors: Mark W. GRINSTAFF, Boris Nicolas BLOCH, Jonah KAPLAN
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Publication number: 20150297316Abstract: The inventions provided herein relate to tissue markers and uses thereof, e.g., to mark a target tissue site (e.g., a biopsy site in a breast tissue) or to produce a cell scaffold. The tissue markers described herein are designed to be resistant to fast migration (e.g., immediate migration after implantation through a needle track) and slow migration (e.g., over an extended period of time) upon implantation at a target tissue site (e.g., a biopsy site in a breast tissue), without using an adhesive. Additionally or alternatively, the tissue markers described herein can be readily detectable by at least one imaging modality, e.g., but not limited to magnetic resonance imaging, X-ray imaging, ultrasound imaging, or a combination thereof.Type: ApplicationFiled: November 21, 2013Publication date: October 22, 2015Inventors: Mark W. GRINSTAFF, Boris Nicolas BLOCH, Jonah KAPLAN
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Publication number: 20100294885Abstract: The invention relates to a storage box (13) in which is received a protective mask (4) adapted to be applied on the face of an aircraft crewmember, said storage box further comprising signaling means (19) activable upon occurrence in the aircraft of a triggering event to help said aircraft crewmember distinguish said storage box from its environment.Type: ApplicationFiled: August 10, 2006Publication date: November 25, 2010Inventors: Nicolas Bloch, Henri Marotte
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Publication number: 20090301489Abstract: The invention relates to a respiratory gas supply circuit (1) for an aircraft carrying passengers and crewmembers (30), comprising a source of breathable gas (R1, R2), at least one supply line (2) connected to said pressurized source, a regulating device (12) provided on said supply line for controlling the supply of breathable gas, a mixing device (9) provided on said supply line, said mixing device further comprising an ambient air inlet (10) for mixing said ambient air with said breathable gas to provide to at least one passenger or crewmember a respiratory gas corresponding to a mixture of said breathable gas and ambient air, wherein said regulating device is driven by a control signal (FIO2R) function at least of the arterial blood oxygen saturation (SaO2) measured on said at least one passenger or crewmember.Type: ApplicationFiled: July 12, 2006Publication date: December 10, 2009Inventors: Nicolas Bloch, Henri Marotte
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Patent number: 7082946Abstract: In order to protect the passengers of an airplane against the effects of depressurization of the cabin, breathing masks are fed with oxygen at a rate which is an increasing function of cabin altitude. Oxygen is fed via a constriction and an economizer bag, and an initial fraction only of the gases breathed out is caused to be re-breathed by collecting the initial fraction in a flexible re-breathing bag in communication with the mask. The re-breathing bag has a volume in inflated state which is not less than the total dead volume of the respiratory tract and the mask. A protective apparatus comprises a feed control unit supplying an adjustable flow rate to masks connected to a general pipe via respective economizer bags. A re-breathing bag retards re-breathing and stores only an initial fraction of the gases breathed out on each exhalation.Type: GrantFiled: October 31, 2002Date of Patent: August 1, 2006Assignee: IntertechniqueInventors: Eric Farin, Michel Bardel, Nicolas Bloch
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Patent number: 6966317Abstract: Individual respiratory gas supply device comprising a respiratory mask and a facial respirator of the cannula or respiratory flexible oro-nasal shell type for comfortably supplying a subject with respiratory gas during a high-altitude flight. The respiratory mask and the facial respirator are adapted so that in the event of de-pressurization or the presence of toxic gases, the subject equips himself with the respiratory mask possibly after having previously removed the facial respirator. Switching means make it possible to cut off the oxygen supply of the facial respirator and dispense oxygen to the regulator when the subject is equipped with the respiratory mask.Type: GrantFiled: July 8, 2003Date of Patent: November 22, 2005Assignee: IntertechniqueInventors: Michel Bardel, Nicolas Bloch, Patrice Martinez
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Publication number: 20040099265Abstract: Individual respiratory gas supply device comprising a respiratory mask and a facial respirator of the cannula or respiratory flexible oro-nasal shell type for comfortably supplying a subject with respiratory gas during a high-altitude flight. The respiratory mask and the facial respirator are adapted so that in the event of de-pressurization or the presence of toxic gases, the subject equips himself with the respiratory mask possibly after having previously removed the facial respirator. Switching means make it possible to cut off the oxygen supply of the facial respirator and dispense oxygen to the regulator when the subject is equipped with the respiratory mask.Type: ApplicationFiled: July 8, 2003Publication date: May 27, 2004Inventors: Michel Bardel, Nicolas Bloch, Patrice Martinez
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Publication number: 20030101997Abstract: In order to protect the passengers of an airplane against the effects of depressurization of the cabin, breathing masks are fed with oxygen at a rate which is an increasing function of cabin altitude. Oxygen is fed via a constriction and an economizer bag, and an initial fraction only of the gases breathed out is caused to be re-breathed by collecting the initial fraction in a flexible re-breathing bag in communication with the mask. The re-breathing bag has a volume in inflated state which is not less than the total dead volume of the respiratory tract and the mask. A protective apparatus comprises a feed control unit supplying an adjustable flow rate to masks connected to a general pipe via respective economizer bags. A re-breathing bag retards re-breathing and stores only an initial fraction of the gases breathed out on each exhalation.Type: ApplicationFiled: October 31, 2002Publication date: June 5, 2003Inventors: Eric Farin, Michel Bardel, Nicolas Bloch
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Patent number: 5636626Abstract: A sealed receptacle (1) contains the additive in liquid phase. A dip tube (3) permits sending the additive to a heating enclosure (5) in which the liquid vaporizes before being sent to a collector-mixer (11) through a constriction (10). The flow rate of additive is controlled by the pressure prevailing above the liquid in the receptacle (1) thanks to a control valve (20) connected by a pressure regulator (25) to a computer (26). This latter receives predetermined values of concentration of the mixture through an input (27). It is preferably connected to a detector (28) of the temperature of the enclosure and/or to an analyzer (30) of the composition of the mixture. Used particularly in anesthesia apparatus.Type: GrantFiled: November 20, 1995Date of Patent: June 10, 1997Assignee: TaemaInventors: Nicolas Bloch, Stephane Ruton
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Patent number: 5549105Abstract: A subassembly constituted by a body and a cover (2), defines internally gas conduit portions (I.sub.i) delimited by partitions of the body coacting with sealing strips (12) in grooves (11) of the cover (2) and formed and mounted in these grooves by injection molding. The sealing strips (12) are recessed within the grooves (11) and coact with the ends of the partitions of the body extending partially into the grooves (11). For use particularly in anesthetic apparatus.Type: GrantFiled: September 9, 1994Date of Patent: August 27, 1996Assignee: L'air Liquide, Societe Anonyme pour l'Etude et l'Exploitation des Procedes Georges ClaudeInventors: Nicolas Bloch, Yvon Guyomard, Michel Jounenc