Patents by Inventor Nicolas Charles

Nicolas Charles has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11908186
    Abstract: Systems and methods for optimizing asset maintenance protocols by predicting vegetation-driven outages are disclosed. An example method includes determining, by one or more processors, a failure probability for each asset in a set of assets within a designated area. The example method further includes defining, by the one or more processors, an asset risk for each asset in the set of assets based on the failure probability, and clustering, by the one or more processors, vegetation within the designated area to determine a predicted vegetation-driven outage. The example method further includes optimizing, by the one or more processors, a set of asset maintenance protocols corresponding to the set of assets based on the asset risk and the predicted vegetation-driven outage.
    Type: Grant
    Filed: March 15, 2023
    Date of Patent: February 20, 2024
    Assignee: MCKINSEY & COMPANY, INC.
    Inventors: Liangliang Zhang, Alfonso Encinas Fernandez, Charlie Gascon, Derek Chu, Kelsey Elwood Carter, Nicolas Charles Michel Bellemans
  • Patent number: 11559513
    Abstract: The present invention concerns a PTGDR-1 antagonist, a PTGDR-2 antagonist, a dual PTGDR-1/PTGDR-1 antagonist, or a combination of PTGDR-1 antagonist and PTGDR-2 antagonist, and pharmaceutical compositions containing them, for use for preventing and/or treating SLE.
    Type: Grant
    Filed: April 13, 2020
    Date of Patent: January 24, 2023
    Assignees: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), UNIVERSITE PARIS CITE
    Inventors: Nicolas Charles, Christophe Pellefigues
  • Patent number: 11280030
    Abstract: A textile jet subassembly includes a textile jet or jet nozzle mounted on a base support. An upper impact plate and a lower insert plate form the yarn channel passing through the jet or jet nozzle. A jet interface and a threading slot communicate with the yarn channel and the sidewalls above and below the threading slot are coplanar to form a smooth surface. Multiple alignment or registration recesses and cooperating pin fasteners are spaced from the yarn channel on the same side of the yarn channel to properly align the side walls above and below the threading slot.
    Type: Grant
    Filed: May 29, 2018
    Date of Patent: March 22, 2022
    Inventor: Nicolas Charles Sear
  • Patent number: 11246980
    Abstract: A pump device (1) for administering a medical fluid to a patient comprises a holding device (10) for receiving a syringe barrel (20) of a syringe (2), the holding device (10) comprising a stationary section (101) and a holding member (11) movable with respect to the stationary section (101) between an opened position and a closed position, wherein the holding member (11) is configured to secure, in the closed position, the syringe barrel (20) of a syringe (2) received on the holding device (10) with respect to the stationary section (101). A shaft (130) is coupled to the holding member (11), the shaft (130) being constituted to rotate during a movement of the holding member (11).
    Type: Grant
    Filed: May 29, 2018
    Date of Patent: February 15, 2022
    Assignee: Fresenius Vial SAS
    Inventors: Fabien Thomas, Rémy Wolff, Nicolas Charles, Denis Bertagnolio
  • Publication number: 20210246442
    Abstract: The present disclosure provides methods for inhibiting and/or reducing self-reactive IgE and/or basophils, thereby treating or preventing lupus, lupus nephritis, and lupus-related disorders.
    Type: Application
    Filed: January 29, 2021
    Publication date: August 12, 2021
    Applicant: The United States of America as represented by the Secretary, Department of Health & Human Services
    Inventors: Juan Rivera, Nicolas Charles
  • Publication number: 20210154393
    Abstract: A pump device (1) for administering a medical fluid to a patient comprises a holding device (10) for receiving a syringe barrel (20) of a syringe (2), the holding device (10) comprising a stationary section (101) and a holding member (11) movable with respect to the stationary section (101) between an opened position and a closed position, wherein the holding member (11) is configured to secure, in the closed position, the syringe barrel (20) of a syringe (2) received on the holding device (10) with respect to the stationary section (101). A shaft (130) is coupled to the holding member (11), the shaft (130) being constituted to rotate during a movement of the holding member (11).
    Type: Application
    Filed: May 29, 2018
    Publication date: May 27, 2021
    Inventors: Fabien Thomas, Rémy Wolff, Nicolas Charles, Denis Bertagnolio
  • Patent number: 10907151
    Abstract: The present disclosure provides methods for inhibiting and/or reducing self-reactive IgE and/or basophils, thereby treating or preventing lupus, lupus nephritis, and lupus-related disorders.
    Type: Grant
    Filed: July 9, 2018
    Date of Patent: February 2, 2021
    Assignee: The United States of America, as Represented By The Secretary, Department of Health and Human Services
    Inventors: Juan Rivera, Nicolas Charles
  • Patent number: 10682886
    Abstract: A non-pneumatic tire is described that includes a ground contacting annular tread portion, a shear band, wherein the shear band is formed of a first and second inextensible layer, and a low modulus material positioned between the first and second inextensible layer. The non-pneumatic tire further includes a connecting web positioned between a hub and the shear band, wherein the connecting web is formed of one or more spokes extending from an inner ring to an outer ring, wherein the one or more spokes are formed from a material reinforced with a three dimensional spacer structure.
    Type: Grant
    Filed: April 5, 2017
    Date of Patent: June 16, 2020
    Assignee: The Goodyear Tire & Rubber Company
    Inventors: William Alain Talbot, Nicolas Charles Louis Bilger, Francesco Sportelli, Samy Laroussi Mzabi, Clemens Manuel Sill, Joseph John Kulig, Gilles Bonnet, Stefan Wilms
  • Publication number: 20190368079
    Abstract: A textile jet subassembly includes a textile jet or jet nozzle mounted on a base support. An upper impact plate and a lower insert plate form the yarn channel passing through the jet or jet nozzle. A jet interface and a threading slot communicate with the yarn channel and the sidewalls above and below the threading slot are coplanar to form a smooth surface. Multiple alignment or registration recesses and cooperating pin fasteners are spaced from the yarn channel on the same side of the yarn channel to properly align the side walls above and below the threading slot.
    Type: Application
    Filed: May 29, 2018
    Publication date: December 5, 2019
    Inventor: Nicolas Charles Sear
  • Publication number: 20180320174
    Abstract: The present disclosure provides methods for inhibiting and/or reducing self-reactive IgE and/or basophils, thereby treating or preventing lupus, lupus nephritis, and lupus-related disorders.
    Type: Application
    Filed: July 9, 2018
    Publication date: November 8, 2018
    Inventors: Juan Rivera, Nicolas Charles
  • Patent number: 10017762
    Abstract: The present disclosure provides methods for inhibiting and/or reducing self-reactive IgE and/or basophils, thereby treating or preventing lupus, lupus nephritis, and lupus-related disorders.
    Type: Grant
    Filed: April 26, 2017
    Date of Patent: July 10, 2018
    Assignee: The United States of America, as represented by the Secretary, Department of Health & Human Services
    Inventors: Juan Rivera, Nicolas Charles
  • Publication number: 20170297372
    Abstract: A non-pneumatic tire is described that includes a ground contacting annular tread portion, a shear band, wherein the shear band is formed of a first and second inextensible layer, and a low modulus material positioned between the first and second inextensible layer. The non-pneumatic tire further includes a connecting web positioned between a hub and the shear band, wherein the connecting web is formed of one or more spokes extending from an inner ring to an outer ring, wherein the one or more spokes are formed from a material reinforced with a three dimensional spacer structure.
    Type: Application
    Filed: April 5, 2017
    Publication date: October 19, 2017
    Inventors: William Alain TALBOT, Nicolas Charles Louis BILGER, Francesco SPORTELLI, Samy Laroussi MZABI, Clemens Manuel SILL, Joseph John KULIG, Gilles BONNET, Stefan WILMS
  • Publication number: 20170275617
    Abstract: The present disclosure provides methods for inhibiting and/or reducing self-reactive IgE and/or basophils, thereby treating or preventing lupus, lupus nephritis, and lupus-related disorders.
    Type: Application
    Filed: April 26, 2017
    Publication date: September 28, 2017
    Inventors: Juan Rivera, Nicolas Charles
  • Patent number: 9657292
    Abstract: The invention features compositions comprising agents that inhibit or reduce self-reactive IgE and/or basophils, and related methods of using the compositions for treating or preventing lupus, lupus nephritis, and lupus-related disorders.
    Type: Grant
    Filed: November 24, 2010
    Date of Patent: May 23, 2017
    Assignee: The United States of America, as represented by the Secretary, Department of Health & Human Services
    Inventors: Juan Rivera, Nicolas Charles
  • Publication number: 20140127199
    Abstract: The invention features compositions comprising agents that inhibit or reduce self-reactive IgE and/or basophils, and related methods of using the compositions for treating or preventing lupus, lupus nephritis, and lupus-related disorders.
    Type: Application
    Filed: November 24, 2010
    Publication date: May 8, 2014
    Applicant: The United States of America,as represented by the Secretary, Department of Health & Human Services
    Inventors: Juan Rivera, Nicolas Charles
  • Publication number: 20130247614
    Abstract: A method or apparatus for securing a first stone to a non-metal mount, the mount comprising a base and a cap which, in cooperation with the base, prevents the first stone from being lost. The first stone may be one of a crystal, a gemstone, a birthstone, a gem, or a similar item. The base may be attached to the cap through the use of screws, snaps, Velcro, glue or a thread connection between the base and the cap. The base may include an elevated pedestal on which the first stone rests, and the elevated pedestal may be configured such that a portion of the first stone extends outside of said cap. The base/cap combination may securely affix the stone between the base and the cap, or it may be designed such that the stone may move between the base and the cap.
    Type: Application
    Filed: March 25, 2012
    Publication date: September 26, 2013
    Inventor: Nicolas Charles THOMAS
  • Publication number: 20120149122
    Abstract: A device for determining the concentration of a compound in an aqueous phase in a dynamic manner and while flowing, and a device (300) for determining the concentration of a compound in a gaseous phase and soluble in an aqueous phase. The device (200, 300) for determining the concentration of a compound in a gaseous phase includes elements (302) for transferring the compounds present in the gaseous phase to an aqueous phase then determining in a dynamic manner and while flowing, the concentration of the compounds in this aqueous phase by fluorescence spectroscopy. The devices (300) are robust, conveyable and less costly, and have greater temporal as well as spatial sensitivity than the devices of the state of the art.
    Type: Application
    Filed: June 8, 2010
    Publication date: June 14, 2012
    Applicants: UNIVERSITE DE STRASBOURG, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Stéphane Cyrille Olivier Le Calve, Wuyin Zheng, Jean-Luc Nicolas Charles Ponche, Pierre Michel Bernhardt
  • Patent number: 6602154
    Abstract: A hydraulic chain tensioner for an internal combustion engine includes a support body forming a cylindrical housing which receives a piston slidable in the housing and which carries a pressure pad acted upon by the piston and arranged to come into contact with the chain. A high-pressure chamber is defined by the housing and the piston. A source of pressurized hydraulic liquid supplies the tensioner with lubricating liquid and completes the filling of the high-pressure chamber.
    Type: Grant
    Filed: December 17, 1999
    Date of Patent: August 5, 2003
    Assignee: Sachs Automotive France, S.A.
    Inventors: Daniel Guichard, Nicolas Charles
  • Patent number: 6478635
    Abstract: In this electrical connection device comprising a female contact (27) which comprises a base portion (28) having, in a first end region (28a), at least one pair of flexible contact blades (29, 30, 31) and, in a second end region (28b), at least one pair of wings (32, 33) adapted to be seated on an electrical current supply conductor, there is provided in the transition region (28c) between the first and second end regions, two wings (34) which are bent toward each other and which bear end to end against each other so as to form with the base portion a closed rigidifying ring (35) which opposes deformation of the first end region (28a) and the modification of the spacing of the contact blades (29, 30, 31) when the wings (32, 33) are seated on the electrical conductor.
    Type: Grant
    Filed: July 18, 2001
    Date of Patent: November 12, 2002
    Assignee: Proner Comatel
    Inventors: Patrick-Nicolas Charles, Bernard Chevalier
  • Publication number: 20020031958
    Abstract: In this electrical connection device comprising a female contact (27) which comprises a base portion (28) having, in a first end region (28a), at least one pair of flexible contact blades (29, 30, 31) and, in a second end region (28b), at least one pair of wings (32, 33) adapted to be seated on an electrical current supply conductor, there is provided in the transition region (28c) between the first and second end regions, two wings (34) which are bent toward each other and which bear end to end against each other so as to form with the base portion a closed rigidifying ring (35) which opposes deformation of the first end region (28a) and the modification of the spacing of the contact blades (29, 30, 31) when the wings (32, 33) are seated on the electrical conductor.
    Type: Application
    Filed: July 18, 2001
    Publication date: March 14, 2002
    Inventors: Patrick-Nicolas Charles, Bernard Chevalier