Patents by Inventor Nicolas D. Vlachakis

Nicolas D. Vlachakis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Radioenzymatic method for assaying normetanephrine
    Patent number: 4275150
    Abstract: Normetanephrine, an N-methylatable phenylethanolamine, is converted to its N-methylated, tritiated derivative, metanephrine, utilizing phenylethanolamine-N-methyltransferase as enzyme and tritiated S-adenosyl-L-methionine as methyl donor. The formed tritiated derivative is selectively extracted in organic solvents and separated from other N-methylatable phenylethanolamines by thin layer chromatography. This assay could be used for measurement of normetanephrine in biological systems of patients with hypertension for detection of pheochromocytoma.
    Type: Grant
    Filed: January 30, 1979
    Date of Patent: June 23, 1981
    Inventor: Nicolas D. Vlachakis