Patents by Inventor Nicolas FAZILLEAU

Nicolas FAZILLEAU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Correlation of disease activity with clonal expansions of human papillomavirus 16-specific CD8+ T-cells in patients with severe erosive oral lichen planus
    Patent number: 10018629
    Abstract: A massive clonal expansion of activated CD8+ T-cells with increased frequency of HPV 16-specific CD8+ T-cells was discovered to be a characteristic of oral lichen planus (OLP), indicating a causal link between HPV infection and the dysimmune process. The invention relates to compositions and methods for the diagnosis and treatment of OLP patients.
    Type: Grant
    Filed: August 8, 2014
    Date of Patent: July 10, 2018
    Assignees: INSTITUTE PASTEUR, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), UNIVERSITE PARIS DIDEROT-PARIS 7, ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS
    Inventors: Marie-Lise Gougeon, Manuelle Viguier, Hervé Bachelez, Nicolas Fazilleau
  • Correlation of disease activity with clonal expansions of human papillomavirus 16-specific CD8+ T-cells in patients with severe erosive oral lichen planus
    Patent number: 9547006
    Abstract: A massive clonal expansion of activated CD8+ T-cells with increased frequency of HPV 16-specific CD8+ T-cells was discovered to be a characteristic of oral lichen planus (OLP), indicating a causal link between HPV infection and the dysimmune process. The invention relates to compositions and methods for the diagnosis and treatment of OLP patients.
    Type: Grant
    Filed: August 8, 2014
    Date of Patent: January 17, 2017
    Assignees: INSTITUT PASTEUR, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), UNIVERSITE PARIS DIDEROT—PARIS 7, ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS
    Inventors: Marie-Lise Gougeon, Manuelle Viguier, Herve Bachelez, Nicolas Fazilleau
  • Immunoadjuvant Compositions and uses Thereof
    Publication number: 20160193328
    Abstract: The present invention relates to an immunoadjuvant composition comprising at least adjuvant and at least one MyD88-dependent pathway agonist.
    Type: Application
    Filed: August 14, 2014
    Publication date: July 7, 2016
    Inventors: Nicolas Fazilleau, Svetoslav Chakarov
  • CORRELATION OF DISEASE ACTIVITY WITH CLONAL EXPANSIONS OF HUMAN PAPILLOMAVIRUS 16-SPECIFIC CD8+ T-CELLS IN PATIENTS WITH SEVERE EROSIVE ORAL LICHEN PLANUS
    Publication number: 20160195531
    Abstract: A massive clonal expansion of activated CD8+ T-cells with increased frequency of HPV 16-specific CD8+ T-cells was discovered to be a characteristic of oral lichen planus (OLP), indicating a causal link between HPV infection and the dysimmune process. The invention relates to compositions and methods for the diagnosis and treatment of OLP patients.
    Type: Application
    Filed: August 8, 2014
    Publication date: July 7, 2016
    Inventors: Marie-Lise GOUGEON, Manuelle VIGUIER, Hervé BACHELEZ, Nicolas FAZILLEAU
  • CORRELATION OF DISEASE ACTIVITY WITH CLONAL EXPANSIONS OF HUMAN PAPILLOMAVIRUS 16-SPECIFIC CD8+ T-CELLS IN PATIENTS WITH SEVERE EROSIVE ORAL LICHEN PLANUS
    Publication number: 20150044252
    Abstract: A massive clonal expansion of activated CD8+ T-cells with increased frequency of HPV 16-specific CD8+ T-cells was discovered to be a characteristic of oral lichen planus (OLP), indicating a causal link between HPV infection and the dysimmune process. The invention relates to compositions and methods for the diagnosis and treatment of OLP patients.
    Type: Application
    Filed: August 8, 2014
    Publication date: February 12, 2015
    Inventors: Marie-Lise GOUGEON, Manuelle VIGUIER, Herve BACHELEZ, Nicolas FAZILLEAU