Patents by Inventor Nicolas Fraunhoffer Navarro

Nicolas Fraunhoffer Navarro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR TREATING LIVER DISEASE
    Publication number: 20220362405
    Abstract: Disclosed are compositions and methods for treating a liver disease in a subject by increasing transport or retention of HNF4?, a transcriptional factor, into a nucleus of a hepatocyte in the subject. In some embodiments, the method comprises upregulating expression or function of one or more transcription factors selected from the group consisting of PROX1, NR5A2, NROB2, MTF1, SREBP1, EP300, and POM121C, and functional fragments thereof, and/or downregulating expression or function of one or more transcription factors DNAJB 1/F1SP40, ATF6, ATF4, and PERK, and functional fragments thereof.
    Type: Application
    Filed: October 14, 2020
    Publication date: November 17, 2022
    Inventors: Alejandro Soto Gutierrez, Aaron Bell, Nicolas Fraunhoffer Navarro, Jorge Guzman Lepe, Sarah Hainer, George K. Michalopoulos, Alina Ostrowska, Ira Fox, Edgar Naoe Tafaleng, Kazuki Takeishi