Abstract: According to the invention there is provided an aerosol-generating device comprising a receiving region configured to receive an aerosol-generating article comprising aerosol-generating substrate. The device further comprises an atomiser configured to heat the aerosol-generating substrate of the aerosol-generating article, when the aerosol-generating article is received in the receiving region. A locking element configured to securely hold the received aerosol-generating article in the receiving region and a controller are further provided. The controller is configured to control the locking element to hold the aerosol-generating article, when the atomiser is activated.

Abstract: Various embodiments are directed to processing and executing digital asset transfers between two users. An example method includes receiving a data object defining a digital asset transfer, and the data object may be a query from the first user to initiate an outbound transfer to a second user or an approval of a request for digital asset units from the second user. The method further includes retrieving account balance data objects associated with the digital asset accounts for the first and second users. The method further includes, responsive to determining that the digital asset transfer satisfies one or more transfer conditions, executing the digital asset transfer by executing a closed-loop debit from the first user and executing a closed-loop credit to the second user. The method further includes updating the account balance data object to reflect the resulting balances of each digital asset account.

Abstract: Various embodiments are directed to processing conversions of digital assets to other digital assets. An example method includes determining a source exchange rate for a source digital asset and a fiat currency, determining a target exchange rate for a target digital asset and a fiat currency, and generating an aggregated conversion rate for the source digital asset and the target digital asset using the source exchange rate and the target exchange rate. The method further includes executing a digital asset conversion, which includes causing source digital asset units to be debited from a source digital asset user account and causing target digital asset units to be credited to a target digital asset user account, and subsequently executing fiat currency transactions (e.g., settlements) with a first digital asset exchange system associated with the source digital asset and a second digital asset exchange system associated with the target digital asset.

Abstract: Various embodiments are directed to processing conversions of digital assets to other digital assets. An example method includes determining a source exchange rate for a source digital asset and a fiat currency, determining a target exchange rate for a target digital asset and a fiat currency, and generating an aggregated conversion rate for the source digital asset and the target digital asset using the source exchange rate and the target exchange rate. The method further includes executing a digital asset conversion, which includes causing source digital asset units to be debited from a source digital asset user account and causing target digital asset units to be credited to a target digital asset user account, and subsequently executing fiat currency transactions (e.g., settlements) with a first digital asset exchange system associated with the source digital asset and a second digital asset exchange system associated with the target digital asset.

Abstract: Various embodiments are directed to processing and executing digital asset transfers between two users. An example method includes receiving a data object defining a digital asset transfer, and the data object may be a query from the first user to initiate an outbound transfer to a second user or an approval of a request for digital asset units from the second user. The method further includes retrieving account balance data objects associated with the digital asset accounts for the first and second users. The method further includes, responsive to determining that the digital asset transfer satisfies one or more transfer conditions, executing the digital asset transfer by executing a closed-loop debit from the first user and executing a closed-loop credit to the second user. The method further includes updating the account balance data object to reflect the resulting balances of each digital asset account.

Abstract: Various embodiments of the present disclosure are generally directed to processing conversions of digital assets to fiat currency. An example method includes obtaining a conversion rate for a digital asset via an API, providing the conversion rate via a client device, receiving a digital asset conversion request and executing a digital asset conversion within a configurable time period. Executing the digital asset conversion includes causing digital asset units to be debited from the digital asset user account and causing fiat currency units to be credited to a fiat currency user account. The method further includes dynamically providing a notification of execution of the digital asset conversion via the client device, updating account balance data objects associated with the digital asset user account and the fiat currency user account, and subsequent to executing the digital asset conversion, executing a fiat currency transaction (e.g., a settlement) with a digital asset exchange system.

Abstract: Various embodiments of the present disclosure are generally directed to processing conversions of digital assets to fiat currency. An example method includes obtaining a conversion rate for a digital asset via an API, providing the conversion rate via a client device, receiving a digital asset conversion request and executing a digital asset conversion within a configurable time period. Executing the digital asset conversion includes causing digital asset units to be debited from the digital asset user account and causing fiat currency units to be credited to a fiat currency user account. The method further includes dynamically providing a notification of execution of the digital asset conversion via the client device, updating account balance data objects associated with the digital asset user account and the fiat currency user account, and subsequent to executing the digital asset conversion, executing a fiat currency transaction (e.g., a settlement) with a digital asset exchange system.

Abstract: Various embodiments are directed to processing and executing digital asset conversions for real-time funding of a merchant transaction involving a user. The user may pre-select digital assets to be converted to fiat currency, and a pre-selected digital asset can be internally-custodied or externally-custodied. An example method includes retrieving a first account balance data object for a fiat currency account associated with the user. The method further includes, responsive to determining that a balance of the fiat currency user account does not satisfy a fiat currency unit threshold of a merchant transaction, retrieving a second account balance data object for a digital asset account associated with the user, determining a conversion rate between a digital asset and a fiat currency, and executing a digital asset conversion by closed-loop debiting digital asset units from the digital asset account and crediting fiat currency units to the fiat currency account.

Abstract: Various embodiments are directed to processing and executing digital asset conversions for real-time funding of a merchant transaction involving an end user. The user may pre-select digital assets to be converted to fiat currency, and a pre-selected digital asset can be internally-custodied or externally-custodied. An example method includes retrieving a first account balance data object for a fiat currency account. The method further includes, responsive to a balance of the fiat currency user account not satisfying a fiat currency unit threshold of a merchant transaction: receiving a second account balance data object for a digital asset account in response to transmitting an account query, determining a conversion rate for a digital asset, and executing a digital asset conversion by causing a debit of digital asset units from the digital asset account via transmitting a conversion execution API query and by crediting fiat currency units to the fiat currency account.

Abstract: Various embodiments are directed to providing digital asset conversion choices involving different digital assets. An example method includes receiving a first digital asset conversion request associated with an end user and indicating a source digital asset and determining a source conversion rate for the source digital asset using an application programming interface (API).

Abstract: According to the invention there is provided an aerosol-generating device comprising a receiving region configured to receive an aerosol-generating article comprising aerosol-generating substrate. The device further comprises an atomiser configured to heat the aerosol-generating substrate of the aerosol-generating article, when the aerosol-generating article is received in the receiving region. A locking element configured to securely hold the received aerosol-generating article in the receiving region and a controller are further provided. The controller is configured to control the locking element to hold the aerosol-generating article, when the atomiser is activated.

Abstract: Various embodiments are directed to processing and executing digital asset transfers between two users. An example method includes receiving a data object defining a digital asset transfer, and the data object may be a query from the first user to initiate an outbound transfer to a second user or an approval of a request for digital asset units from the second user. The method further includes receiving account data for the first and second users via application programming interface (API) communication with an external system, and responsive to determining that transfer conditions are satisfied, executing the digital asset transfer by causing the external system to debit digital asset units from the first user and to credit digital asset units to the second user via API communication with the external system. The method further includes updating the account data to reflect account balances resulting from the debit and the credit.

Abstract: Various embodiments are directed to processing and executing digital asset transfers between two users. An example method includes receiving a data object defining a digital asset transfer, and the data object may be a query from the first user to initiate an outbound transfer to a second user or an approval of a request for digital asset units from the second user. The method further includes retrieving account balance data objects associated with the digital asset accounts for the first and second users. The method further includes, responsive to determining that the digital asset transfer satisfies one or more transfer conditions, executing the digital asset transfer by executing a closed-loop debit from the first user and executing a closed-loop credit to the second user. The method further includes updating the account balance data object to reflect the resulting balances of each digital asset account.

Abstract: Various embodiments are directed to processing conversions of digital assets to other digital assets. An example method includes determining a source exchange rate for a source digital asset and a fiat currency, determining a target exchange rate for a target digital asset and a fiat currency, and generating an aggregated conversion rate for the source digital asset and the target digital asset using the source exchange rate and the target exchange rate. The method further includes executing a digital asset conversion, which includes causing source digital asset units to be debited from a source digital asset user account and causing target digital asset units to be credited to a target digital asset user account, and subsequently executing fiat currency transactions (e.g., settlements) with a first digital asset exchange system associated with the source digital asset and a second digital asset exchange system associated with the target digital asset.

Abstract: Various embodiments of the present disclosure are generally directed to processing conversions of digital assets to fiat currency. An example method includes obtaining a conversion rate for a digital asset via an API, providing the conversion rate via a client device, receiving a digital asset conversion request and executing a digital asset conversion within a configurable time period. Executing the digital asset conversion includes causing digital asset units to be debited from the digital asset user account and causing fiat currency units to be credited to a fiat currency user account. The method further includes dynamically providing a notification of execution of the digital asset conversion via the client device, updating account balance data objects associated with the digital asset user account and the fiat currency user account, and subsequent to executing the digital asset conversion, executing a fiat currency transaction (e.g., a settlement) with a digital asset exchange system.

Abstract: A nutraceutical composition comprising prebiotics, probiotics, and/or synbiotics, spirulina, cereals and micronutrients for improving a person's health, and methods for boosting the immune system and improving vaccine effectiveness in vulnerable populations with the nutraceutical composition, including undernourished children, lactating and pregnant mothers in LDCs, the elderly, and persons with cancer or at risk of developing cancer.

Abstract: Various embodiments of the present disclosure provide methods, apparatuses, systems, devices, computing entities for managing digital asset transactions. An example method includes obtaining first current pricing data via an application programming interface, and providing the first current pricing data via a client device. The method further includes, responsive to determining that a first configurable time period has elapsed: obtaining second current pricing data via an application programming interface, and providing the second current pricing data for display via the client device. The method further includes receiving a second transaction request and executing an off-chain digital asset transaction for the second transaction request between a central operating account and the internal user account within a second configurable time period.

Abstract: Simian adenoviral vectors and RNA molecules, each encoding an immunogen of interest, can be sequentially administered to provide potent and long-lasting immunity.

Abstract: A heat exchanger has oil core plates and coolant core plates disposed in alternating, stacked relationship. Flow passages are provided between adjacent plates, so that the oil flow passages alternate with the coolant flow passages, and the oil can flow from an oil inlet opening of each oil plate, and through the oil flow passage to an oil outlet opening, and coolant can flow from a coolant inlet opening of each coolant plate through the coolant flow passage to a coolant outlet opening. The oil inlet openings are adjacent one end of the plates, and the oil outlet openings are spaced from the oil inlet openings, with a passageway for flow of the oil between upstanding bosses of the coolant plates on opposed sides of each oil plate and extending from a gap in an upstanding flange of the oil plate to the oil outlet opening.

Abstract: A heat exchanger has a plurality of oil core plates, and a plurality of coolant core plates, with each plate having an oil inlet opening adjacent one end of the plate, an oil outlet opening spaced from the oil inlet opening towards an opposed end of the plate, a coolant inlet opening, and a coolant outlet opening, and with the coolant inlet and outlet openings being adjacent the opposed end of the plate. Each oil core plate has an inwardly inclined, upstanding flange surrounding the oil inlet opening in the plate except for a portion thereof adjacent the one end of the plate at which a gap is provided in the flange. The oil outlet opening in the plate extends to adjacent the opposed end of the plate, and a further inwardly inclined, upstanding flange surrounds the oil outlet opening in the plate except adjacent the opposed end of the plate at which a further gap or gaps are provided in the further flange.