Patents by Inventor Nicolas J. Pacelli

Nicolas J. Pacelli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210128463
    Abstract: Drug delivery devices and methods of controlled drug delivery to a patient are provided. The drug delivery device may include one or two microchip elements, each of which has a body portion with one or more drug release apertures in fluid communication with at least one containment reservoir. The drug release apertures are closed off by one or more reservoir caps which can be electrically activated to open the drug release apertures. The drug delivery device also includes (i) a drug formulation disposed in the at least one containment reservoir, and (ii) at least one drug-permeable membrane. In some cases, an outer housing is spaced a distance from an exterior wall of the body portion of the microchip element, the outer housing includes the at least one drug-permeable membrane, and a depot space is defined between the drug-permeable membrane and the exterior wall of the body portion of the microchip element.
    Type: Application
    Filed: October 30, 2020
    Publication date: May 6, 2021
    Inventors: Robert Farra, Elizabeth Proos, Scott W. James, Nicolas J. Pacelli, Hong-Ren Wang
  • Patent number: 8545499
    Abstract: An expandable rod is provided that is sized for insertion into a patient's bone. A method for using the expandable rod to prepare the patient's bone to receive an orthopedic implant is also provided. The expandable rod is adjustable between a first, contracted state and a second, expanded state, the expansion member expanding radially outwardly from the contracted state to the expanded state.
    Type: Grant
    Filed: September 27, 2010
    Date of Patent: October 1, 2013
    Assignee: Zimmer, Inc.
    Inventors: Antony J. Lozier, Daniel P. Murphy, Justin J. May, Shanon N. Roberts, Andrew L. Gray, Nicolas J. Pacelli
  • Patent number: 8012155
    Abstract: A method and apparatus configured to strengthen and support a portion of a bone, such as the femoral head of the proximal femur, for example. The apparatus may include a housing or base member and a movable support member connected to the housing and configured to move between a first, undeployed position in which the support member is disposed proximate the housing or base such that the apparatus may be inserted into bone, and a second, deployed position in which the support member extends away from the housing or base for supporting the femoral head. The support member may be a rod, one or more wires, a leaf spring, a bladder, or an expandable mesh material, for example.
    Type: Grant
    Filed: April 2, 2009
    Date of Patent: September 6, 2011
    Assignee: Zimmer, Inc.
    Inventors: Matthew P. Prygoski, Antony J. Lozier, Russell M. Parrott, Andrew L. Gray, Nicolas J. Pacelli
  • Publication number: 20110077651
    Abstract: An expandable rod is provided that is sized for insertion into a patient's bone. A method for using the expandable rod to prepare the patient's bone to receive an orthopedic implant is also provided. The expandable rod is adjustable between a first, contracted state and a second, expanded state, the expansion member expanding radially outwardly from the contracted state to the expanded state.
    Type: Application
    Filed: September 27, 2010
    Publication date: March 31, 2011
    Applicant: ZIMMER, INC.
    Inventors: Antony J. Lozier, Daniel P. Murphy, Justin J. May, Shanon N. Roberts, Andrew L. Gray, Nicolas J. Pacelli
  • Publication number: 20100256640
    Abstract: A method and apparatus configured to strengthen and support a portion of a bone, such as the femoral head of the proximal femur, for example. The apparatus may include a housing or base member and a movable support member connected to the housing and configured to move between a first, undeployed position in which the support member is disposed proximate the housing or base such that the apparatus may be inserted into bone, and a second, deployed position in which the support member extends away from the housing or base for supporting the femoral head. The support member may be a rod, one or more wires, a leaf spring, a bladder, or an expandable mesh material, for example.
    Type: Application
    Filed: April 2, 2009
    Publication date: October 7, 2010
    Applicant: ZIMMER, INC.
    Inventors: Matthew P. Prygoski, Antony J. Lozier, Russell M. Parrott, Andrew L. Gray, Nicolas J. Pacelli
  • Patent number: 7488329
    Abstract: An improved apparatus for reducing a hip fracture utilizing a minimally invasive procedure which does not require incision of the quadriceps. A femoral implant in accordance with the present invention achieves intramedullary fixation as well as fixation into the femoral head to allow for the compression needed for a femoral fracture to heal. An alignment guide in accordance with the present invention is provided to facilitate alignment of instruments used to create a cavity in the bone for reception of the femoral implant and to facilitate size selection of the femoral implant. The alignment guide of the present invention includes a reference element and pattern arms having geometries which track an anatomical structure.
    Type: Grant
    Filed: February 18, 2005
    Date of Patent: February 10, 2009
    Assignee: Zimmer Technology, Inc.
    Inventors: Sarah L Thelen, Antony J Lozier, Nicolas J Pacelli
  • Patent number: 7485119
    Abstract: A method and apparatus for reducing a hip fracture utilizing a minimally invasive procedure. A femoral implant achieves intramedullary fixation as well as fixation into the femoral head. To optimally position the femoral implant, a minimally invasive incision is aligned with the greater trochanter and the wound is developed to expose the greater trochanter. Various reamers are utilized to prepare a cavity in the femur extending from the greater trochanter into the femoral head and further extending from the greater trochanter into the intramedullary canal of the femur.
    Type: Grant
    Filed: October 14, 2005
    Date of Patent: February 3, 2009
    Assignee: Zimmer Technology, Inc.
    Inventors: Sarah L. Thelen, Antony J. Lozier, Nicolas J. Pacelli
  • Publication number: 20030220644
    Abstract: An improved method and apparatus for reducing a hip fracture utilizing a minimally invasive procedure which does not require incision of the quadriceps. A femoral implant in accordance with the present invention achieves intramedullary fixation as well as fixation into the femoral head to allow for the compression needed for a femoral fracture to heal. To position the femoral implant of the present invention, an incision is made along the greater trochanter. Because the greater trochanter is not circumferentially covered with muscles, the incision can be made and the wound developed through the skin and fascia to expose the greater trochanter, without incising muscle, including, e.g., the quadriceps. After exposing the greater trochanter, novel instruments of the present invention are utilized to prepare a cavity in the femur extending from the greater trochanter into the femoral head and further extending from the greater trochanter into the intramedullary canal of the femur.
    Type: Application
    Filed: February 4, 2003
    Publication date: November 27, 2003
    Inventors: Sarah L. Thelen, Antony J. Lozier, Nicolas J. Pacelli, Michael A. Liberti, Mark A. Bryant, Billy N. Sisk, Jack D. Jennings
  • Publication number: 20030220646
    Abstract: An improved method and apparatus for reducing a hip fracture utilizing a minimally invasive procedure which does not require incision of the quadriceps. A femoral implant in accordance with the present invention achieves intramedullary fixation as well as fixation into the femoral head to allow for the compression needed for a femoral fracture to heal. To position the femoral implant of the present invention, an incision is made along the greater trochanter. Because the greater trochanter is not circumferentially covered with muscles, the incision can be made and the wound developed through the skin and fascia to expose the greater trochanter, without incising muscle, including, e.g., the quadriceps. After exposing the greater trochanter, novel instruments of the present invention are utilized to prepare a cavity in the femur extending from the greater trochanter into the femoral head and further extending from the greater trochanter into the intramedullary canal of the femur.
    Type: Application
    Filed: October 8, 2002
    Publication date: November 27, 2003
    Inventors: Sarah L. Thelen, Antony J. Lozier, Nicolas J. Pacelli, Michael Andrew Liberti, Michael E. Hawkins, Billy N. Sisk, Rick Miller