Abstract: The present invention provides a stent assembly for expanding a bodily passage in a patient and draining a fluid therefrom. The assembly comprises at least one expandable stent and an elongated carrier for delivery or retrieval of the stent. The stent is circumferentially attached to a distal end of the carrier. The carrier defines at least two concentric lumens therethrough, a drainage lumen in fluid communication with the bodily passage for drainage of the fluid and an inflation lumen in fluid communication with the expandable stent. The invention also provides a method of expanding a bodily passage in a patient and draining a fluid therefrom. The method comprises providing a stent assembly of the present invention; inserting a guidewire into the bodily passage through the drainage lumen of the carrier; advancing the assembly along the guidewire until the assembly reaches a desired location; expanding the stent; and draining the fluid through drainage lumen of the carrier.

Abstract: A method of treating or preventing a pathological condition of the uterus in an individual the method comprising administering to the individual any one or more of an inhibitor of cyclooxygenase-2 (COX-2), an inhibitor of prostaglandin E synthase (PGES), or an EP2 or EP4 receptor antagonist. Typically, the pathological condition is uterine cancer, fibroids or endometriosis.

Abstract: A method of combating menorrhagia, dysmenorrhoea or endometriosis in a female individual that includes administering to the individual at least one agent that reduces the effect of prokineticin 1 on a prokineticin receptor.

Abstract: The present invention is directed to implantable devices and systems for the differential monitoring the condition of the tissue or fluid emitted from the site in proximity to the implants.

Abstract: The present invention is directed to implantable devices and systems for the differential monitoring the condition of the tissue or fluid emitted from the site in proximity to the implants. The invention may also include modifications of the implantable device to stabilize or immobilize the device in the proximity of the tissue to be monitored.

Abstract: A method of treating menorrhagia and/or dysmenorrhoea in a patient the method comprising administering to the patient an antagonist of a prostaglandin EP2 and/or EP4 receptor. Preferably the patient is a human female.

Abstract: A method of treating an individual with a condition which condition is one wherein the individual with the condition benefits from the administration of GnRH and/or a GnRH analogue, the method comprising administering to the individual GnRH and/or a GnRH analogue and an inhibitor of prostaglandin synthesis and/or a prostaglandin receptor antagonist. The methods of the invention also include combating a sex-hormone dependent disease in an individual, and regulating fertility in an individual.

Abstract: The present invention is directed to devices and methods of using a surgical drain, and more particularly to a surgical drain having at least one sensor for monitoring and/or recording the condition of the anatomical site or fluid emitted from the site where the surgical drain is placed. The invention may also include modifications of the surgical drain to improve stabilization or immobilization in the proximity of the anatomical site to be monitored.

Abstract: The present invention is directed to devices and methods of using a surgical drain, and more particularly to a surgical drain having at least one sensor for monitoring and/or recording the condition of the anatomical site or fluid emitted from the site where the surgical drain is placed. The invention may also include modifications of the surgical drain to improve stabilization or immobilization in the proximity of the anatomical site to be monitored.

Abstract: The present invention is directed to devices and methods of using a surgical drain, and more particularly to a surgical drain having at least one sensor for monitoring and/or recording the condition of the anatomical site or fluid emitted from the site where the surgical drain is placed. The invention may also include modifications of the surgical drain to improve stabilization or immobilization in the proximity of the anatomical site to be monitored.

Abstract: The present invention is directed to devices and methods of using a surgical drain, and more particularly to a surgical drain having at least one sensor for monitoring and/or recording the condition of the anatomical site or fluid emitted from the site where the surgical drain is placed. The invention may also include modifications of the surgical drain to improve stabilization or immobilization in the proximity of the anatomical site to be monitored.

Abstract: A method of decreasing excessive portal venous inflow during liver transplantation is provided. The technique involves the use of a temporary left portahepatic shunt. This allows portasystemic decompression during implantation of donor liver and diverts mesenteric blood from the donor liver during the crucial period after unclamping in liver transplantation. The method can be used for any type of liver transplantation and is particularly advantageous for live donor liver transplantation.

Abstract: The present invention is directed to devices and methods of using a surgical drain, and more particularly to a surgical drain having at least one sensor for monitoring and/or recording the condition of the anatomical site or fluid emitted from the site where the surgical drain is placed. The invention may also include modifications of the surgical drain to improve stabilization or immobilization in the proximity of the anatomical site to be monitored.

Abstract: The present invention is directed to devices and methods of using a surgical drain, and more particularly to a surgical drain having at least one sensor for monitoring and/or recording the condition of the anatomical site or fluid emitted from the site where the surgical drain is placed. The invention may also include modifications of the surgical drain to improve stabilization or immobilization in the proximity of the anatomical site to be monitored.

Abstract: The present invention provides a stent assembly for expanding a bodily passage in a patient and draining a fluid therefrom. The assembly comprises at least one expandable stent and an elongated carrier for delivery or retrieval of the stent. The stent is circumferentially attached to a distal end of the carrier. The carrier defines at least two concentric lumens therethrough, a drainage lumen in fluid communication with the bodily passage for drainage of the fluid and an inflation lumen in fluid communication with the expandable stent. The invention also provides a method of expanding a bodily passage in a patient and draining a fluid therefrom. The method comprises providing a stent assembly of the present invention; inserting a guidewire into the bodily passage through the drainage lumen of the carrier; advancing the assembly along the guidewire until the assembly reaches a desired location; expanding the stent; and draining the fluid through drainage lumen of the carrier.

Abstract: The present invention is directed to devices and methods of using a surgical drain, and more particularly to a surgical drain having at least one sensor for monitoring and/or recording the condition of the anatomical site or fluid emitted from the site where the surgical drain is placed. The invention may also include modifications of the surgical drain to improve stabilization or immobilization in the proximity of the anatomical site to be monitored.

Abstract: The present invention is directed to implantable devices and systems for the differential monitoring the condition of the tissue or fluid emitted from the site in proximity to the implants. The invention may also include modifications of the implantable device to stabilize or immobilize the device in the proximity of the tissue to be monitored.

Abstract: The present invention is directed to devices and methods of using a surgical drain, and more particularly to a surgical drain having at least one sensor for monitoring and/or recording the condition of the anatomical site or fluid emitted from the site where the surgical drain is placed. The invention may also include modifications of the surgical drain to improve stabilization or immobilization in the proximity of the anatomical site to be monitored.

Abstract: A method of treating a neoplastic condition of the cervix in a patient the method comprising administering to the patient an inhibitor of cyclooxygenase-1 (COX-1) and/or an EP2 and/or EP4 receptor antagonist

Abstract: A method of treating or preventing a pathological condition of the uterus in an individual the method comprising administering to the individual any one or more of an inhibitor of cyclooxygenase-2 (COX-2), an inhibitor of prostaglandin E synthase (PGES), or an EP2 or EP4 receptor antagonist. Typically, the pathological condition is uterine cancer, fibroids or endometriosis.