Abstract: The present invention provides a compound of Formula I: or a pharmaceutically acceptable salt thereof, and the use of compounds of Formula I for treating neurodegenerative diseases, such as Alzheimers disease.

Abstract: Systems and methods for preparing and analyzing data related to geo-spatial properties. A system generates from a first data source, based on an ontology, a geographic dataset including first data objects representative of first data from the first data source and at least one geo-spatial reference based on respective location information from the first data source that corresponds to the first data. The system can also generate a vector map data tile layer based on the ontology using the geographic dataset and including vector map data tiles, having map geometry data linked to the first data objects by a geo-spatial reference, and corresponding to a portion of a geographic area represented by the vector map data tile layer. In response to requests from the front-end system application for first data related to a geo-spatial feature, tiles can be provided and first data corresponding to selected geo-spatial references can be displayed.

Abstract: A method of host-directed illumination for verifying the validity of biometric data of a user is provided that includes capturing biometric data from a user with an authentication device during authentication and directing illumination of the biometric data from a host authentication system during the capturing operation. Moreover, the method includes comparing illumination characteristics of the captured biometric data against illumination characteristics expected to result from the directing operation, and determining that the user is a live user when the illumination characteristics of the captured biometric data match the illumination characteristics expected to result from the directing operation.

Abstract: A method for determining authenticity of a document is provided that includes receiving, by an electronic device, an image of a document, assigning a label to the image, and obtaining vectors for each image in a subset of images. Each image is of a document and is assigned the same label as the received image. Moreover, the method includes encoding the received image into a vector, calculating a distance between the vector of the received image and each obtained vector, comparing each of the calculated distances against a threshold distance, and calculating a number of the calculated distances that are less than or equal to the threshold distance. In response to determining the calculated number is at least equal to a required number, the document in the received image is determined to be authentic. Otherwise, the received image requires manual review.

Abstract: A method of host-directed illumination for verifying the validity of biometric data of a user is provided that includes capturing biometric data from a user with an authentication device during authentication and directing illumination of the biometric data from a host authentication system during the capturing operation. Moreover, the method includes comparing illumination characteristics of the captured biometric data against illumination characteristics expected to result from the directing operation, and determining that the user is a live user when the illumination characteristics of the captured biometric data match the illumination characteristics expected to result from the directing operation.

Abstract: Systems and methods for preparing and analyzing data related to geo-spatial properties. A system generates from a first data source, based on an ontology, a geographic dataset including first data objects representative of first data from the first data source and at least one geo-spatial reference based on respective location information from the first data source that corresponds to the first data. The system can also generate a vector map data tile layer based on the ontology using the geographic dataset and including vector map data tiles, having map geometry data linked to the first data objects by a geo-spatial reference, and corresponding to a portion of a geographic area represented by the vector map data tile layer. In response to requests from the front-end system application for first data related to a geo-spatial feature, tiles can be provided and first data corresponding to selected geo-spatial references can be displayed.

Abstract: A method of host-directed illumination for verifying the validity of biometric data of a user is provided that includes capturing biometric data from a user with an authentication device during authentication and directing illumination of the biometric data from a host authentication system during the capturing operation. Moreover, the method includes comparing illumination characteristics of the captured biometric data against illumination characteristics expected to result from the directing operation, and determining that the user is a live user when the illumination characteristics of the captured biometric data match the illumination characteristics expected to result from the directing operation.

Abstract: Systems and methods for preparing and analyzing data related to geo-spatial properties. A system generates from a first data source, based on an ontology, a geographic dataset including first data objects representative of first data from the first data source and at least one geo-spatial reference based on respective location information from the first data source that corresponds to the first data. The system can also generate a vector map data tile layer based on the ontology using the geographic dataset and including vector map data tiles, having map geometry data linked to the first data objects by a geo-spatial reference, and corresponding to a portion of a geographic area represented by the vector map data tile layer. In response to requests from the front-end system application for first data related to a geo-spatial feature, tiles can be provided and first data corresponding to selected geo-spatial references can be displayed.

Abstract: Systems and methods for preparing and analyzing data related to geo-spatial properties. A system generates from a first data source, based on an ontology, a geographic dataset including first data objects representative of first data from the first data source and at least one geo-spatial reference based on respective location information from the first data source that corresponds to the first data. The system can also generate a vector map data tile layer based on the ontology using the geographic dataset and including vector map data tiles, having map geometry data linked to the first data objects by a geo-spatial reference, and corresponding to a portion of a geographic area represented by the vector map data tile layer. In response to requests from the front-end system application for first data related to a geo-spatial feature, tiles can be provided and first data corresponding to selected geo-spatial references can be displayed.

Abstract: The present invention provides a compound of Formula I: wherein R is H or F; or a pharmaceutically acceptable salt thereof, and the use of compounds of Formula I for treatment of neurodegenerative diseases, such as Alzheimer's disease.

Abstract: The present invention provides a compound of Formula I: or a pharmaceutically acceptable salt thereof, and the use of compounds of Formula I for treating neurodegenerative diseases, such as Alzheimers disease.

Abstract: New pyrimidine derivatives together with a membrane penetrating agent, optionally with a detectable isotope and pharmaceutical composition for use in treatment or prevention of Gram-negative bacterial infection in a host mammal in need of such treatment or prevention and use as inhibitors of Gram-negative biofilm formation on a surface of biomaterial or medical device, particularly of cardiovascular device such as prosthetic heart valve or pacemakers. New pyrimidine derivatives together with a membrane penetrating agent; for use as radiotracer in diagnosing or prognosing Gram-negative bacterial infection in a host mammal.

Abstract: A method of host-directed illumination for verifying the validity of biometric data of a user is provided that includes capturing biometric data from a user with an authentication device during authentication and directing illumination of the biometric data from a host authentication system during the capturing operation. Moreover, the method includes comparing illumination characteristics of the captured biometric data against illumination characteristics expected to result from the directing operation, and determining that the user is a live user when the illumination characteristics of the captured biometric data match the illumination characteristics expected to result from the directing operation.

Abstract: A method of host-directed illumination for verifying the validity of biometric data of a user is provided that includes capturing biometric data from a user with an authentication device during authentication and directing illumination of the biometric data from a host authentication system during the capturing operation. Moreover, the method includes comparing illumination characteristics of the captured biometric data against illumination characteristics expected to result from the directing operation, and determining that the user is a live user when the illumination characteristics of the captured biometric data match the illumination characteristics expected to result from the directing operation.

Abstract: The present invention provides a compound of Formula I: wherein R is H or F; or a pharmaceutically acceptable salt thereof, and the use of compounds of Formula I for treatment of neurodegenerative diseases, such as Alzheimer's disease.

Abstract: The present invention provides a compound of Formula I: wherein R is hydrogen or methyl; and Z is: or a pharmaceutically acceptable salt thereof, and the use of compounds of Formula I for treating neurodegenerative diseases, such as Alzheimer's disease.

Abstract: The present invention provides a compound of Formula I: wherein R is hydrogen or methyl; and Z is: or a pharmaceutically acceptable salt thereof, and the use of compounds of Formula I for treating neurodegenerative diseases, such as Alzheimer's disease.

Abstract: The present invention provides a compound of Formula I: wherein R is hydrogen or methyl; and Z is: or a pharmaceutically acceptable salt thereof, and the use of compounds of Formula I for treating neurodegenerative diseases, such as Alzheimer's disease.

Abstract: A method of host-directed illumination for verifying the validity of biometric data of a user is provided that includes capturing biometric data from a user with an authentication device during authentication and directing illumination of the biometric data from a host authentication system during the capturing operation. Moreover, the method includes comparing illumination characteristics of the captured biometric data against illumination characteristics expected to result from the directing operation, and determining that the user is a live user when the illumination characteristics of the captured biometric data match the illumination characteristics expected to result from the directing operation.

Abstract: A method of capturing biometric data is provided that includes activating a security application in a device. The security application is activated by an operator of the device and is configured to cause the device to display an outline image. Moreover, the method includes displaying the outline image in a stationary position on a display of the device, positioning desired biometric data proximate the device such that the desired biometric data appears as a biometric image on the device display, and monitoring the outline and biometric images shown on the device display. Furthermore, the method includes positioning the device and the desired biometric data to better align the outline and biometric images when the outline and biometric images do not align and capturing the desired biometric data from an individual after approximately aligning the outline image with the biometric image.