Abstract: An apparatus suitable for clamping at least one microfluidic device, which includes (i) a fluid-tight chamber having a fluid inlet, the chamber being configured to receive a microfluidic device to be clamped by compression of at least one deformable part of the microfluidic device under the action of a pressure of a clamping fluid in the chamber, and (ii) a perfusion fluid management system configured to adjust the pressure of a perfusion fluid in the microfluidic device in such a way that, during a clamping operation, the pressure of the clamping fluid in the chamber is strictly higher than the pressure of the perfusion fluid in the microfluidic device.

Abstract: This molding apparatus is intended for the manufacturing of a molded article from a raw material intended to be arranged in a first region of an embossing chamber of the molding apparatus. The embossing chamber includes a mold and a counter-mold, the molds being arranged on two opposite sides of the first region. The molding apparatus further includes a second chamber having a common wall with the embossing chamber and a pressurization system configured to generate a predefined pressure differential between the embossing chamber and the second chamber, the common wall including at least one embossing actuator, the embossing actuator being configured to generate a movement of at least one of the molds so as to mold the raw material when a predefined pressure differential is applied.

Abstract: An apparatus suitable for clamping at least one microfluidic device, which includes (i) a fluid-tight chamber having a fluid inlet, the chamber being configured to receive a microfluidic device to be clamped by compression of at least one deformable part of the microfluidic device under the action of a pressure of a clamping fluid in the chamber, and (ii) a perfusion fluid management system configured to adjust the pressure of a perfusion fluid in the microfluidic device in such a way that, during a clamping operation, the pressure of the clamping fluid in the chamber is strictly higher than the pressure of the perfusion fluid in the microfluidic device.

Abstract: A microfluidic device for processing particles, including: an elongated chamber including elongated segment(s), input seeding channel(s) and one output seeding channel defining a seeding flow transverse to the longitudinal direction of the segment, input harvest channel(s) and one output harvest channel defining a harvest flow in the longitudinal direction, wherein, for the segment, a single input seeding tree defines input seeding channels and a single output seeding tree defines output seeding channels, junctions of the input seeding channels and output seeding channels with the processing chamber being distributed along the segment on both sides of the chamber, wherein: Rs_input ? S 2 ? 1 ( ? k ? V k * S k ) / V TOTs ? _ ? inpu ? t is higher than 50, S21 being the segment cross section perpendicular to the transverse direction, (?k Vk*Sk)/VTOTs_input being, the sum of the products of the volume and the cross section of the input seeding channel, divided by the total volume V