Patents by Inventor Nicolas Lecointe

Nicolas Lecointe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11530227
    Abstract: The present invention relates to compounds of formula (I) and their use for treating or preventing a bacterial infection or as an antibacterial agent and/or as a ?-lactamase inhibitor.
    Type: Grant
    Filed: July 30, 2019
    Date of Patent: December 20, 2022
    Assignee: MUTABILIS
    Inventors: Julien Barbion, Audrey Caravano, Sophie Chasset, Francis Chevreuil, Nicolas Lecointe, Frédéric Le Strat, Chrystelle Oliveira, Christophe Simon
  • Publication number: 20210277019
    Abstract: The present invention relates to compounds of formula (I) and their use for treating or preventing a bacterial infection or as an antibacterial agent and/or as a ?-lactamase inhibitor.
    Type: Application
    Filed: July 30, 2019
    Publication date: September 9, 2021
    Inventors: Julien Barbion, Audrey Caravano, Sophie Chasset, Francis Chevreuil, Nicolas Lecointe, Frédéric Le Strat, Chrystelle Oliveira, Christophe Simon
  • Patent number: 10842779
    Abstract: The present invention relates to heterocyclic compounds, their process of preparation, pharmaceutical compositions comprising these compounds and use thereof, optionally in combination with other antibacterial agents and/or beta-lactam compounds, for the prevention or treatment of bacterial infections. The present invention also relates to the use of these compounds as ?-lactamase inhibitors and/or as antibacterial agents.
    Type: Grant
    Filed: December 22, 2016
    Date of Patent: November 24, 2020
    Assignee: MUTABILIS
    Inventors: Julie Brias, Sophie Chasset, Francis Chevreuil, Nicolas Lecointe, Benoit Ledoussal, Frédéric Le Strat, Julien Barbion
  • Patent number: 10722520
    Abstract: A compound of formula (I) or a racemate, an enantiomer, a diastereoisomer, a geometric isomer or a pharmaceutically acceptable salt thereof, and its use as antibacterial agent.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: July 28, 2020
    Assignee: MUTABILIS
    Inventors: Julien Barbion, Audrey Caravano, Sophie Chasset, Francis Chevreuil, Fabien Faivre, Rémi Lebel, Nicolas Lecointe, Benoît Ledoussal, Frédéric Le-Strat, Christophe Simon, Chrystelle Oliveira, Géraldine Le Fralliec, Julie Brias, Laurence Farescour, Sophie Vomscheid, Sébastien Richard
  • Publication number: 20200017495
    Abstract: The present invention relates to compound of formula (I) and their use for treating bacterial infections.
    Type: Application
    Filed: February 6, 2018
    Publication date: January 16, 2020
    Inventors: Damien Bonnard, Julie Brias, Julien Barbion, Audrey Caravano, Sophie Chasset, Francis Chevreuil, Nicolas Lecointe, Benoît Ledoussal, Erwann Le Rouzic, Frédéric Le Strat, François Moreau, Marie-Hélène Quernin, Ludovic Waeckel
  • Patent number: 10501481
    Abstract: The present invention relates to heterocyclic compounds, their process of preparation, pharmaceutical compositions comprising these compounds and use thereof, optionally in combination with other antibacterial agents and/or beta-lactam compounds, for the prevention or treatment of bacterial infections. The present invention also relates to the use of these compounds as ?-lactamase inhibitors and/or as antibacterial agents.
    Type: Grant
    Filed: April 1, 2016
    Date of Patent: December 10, 2019
    Assignee: MUTABILIS
    Inventors: Julie Brias, Sophie Chasset, Francis Chevreuil, Nicolas Lecointe, Benôit Ledoussal, Frédéric Le Strat, Sophie Vomscheid, Sébastien Richard, Fabien Faivre, Julien Barbion, Audrey Caravano, Géraldine Le Fralliec, Christophe Simon
  • Publication number: 20190224210
    Abstract: A compound of formula (I) or a racemate, an enantiomer, a diastereoisomer, a geometric isomer or a pharmaceutically acceptable salt thereof, and its use as antibacterial agent.
    Type: Application
    Filed: September 29, 2017
    Publication date: July 25, 2019
    Inventors: Julien BARBION, Audrey CARAVANO, Sophie CHASSET, Francis CHEVREUIL, Fabien FAIVRE, Rémi LEBEL, Nicolas LECOINTE, Benoît LEDOUSSAL, Frédéric LE-STRAT, Christophe SIMON, Chrystelle OLIVEIRA, Géraldine LE FRALLIEC, Julie BRIAS, Laurence FARESCOUR, Sophie VOMSCHEID, Sébastien RICHARD
  • Publication number: 20190175561
    Abstract: The present invention relates to heterocyclic compounds, their process of preparation, pharmaceutical compositions comprising these compounds and use thereof, optionally in combination with other antibacterial agents and/or beta-lactam compounds, for the prevention or treatment of bacterial infections. The present invention also relates to the use of these compounds as ?-lactamase inhibitors and/or as antibacterial agents.
    Type: Application
    Filed: December 22, 2016
    Publication date: June 13, 2019
    Applicant: MUTABILIS
    Inventors: Julie BRIAS, Sophie CHASSET, Francis CHEVREUIL, Nicolas LECOINTE, Benoît LEDOUSSAL, Frédéric LE STRAT, Julien BARBION
  • Patent number: 10301305
    Abstract: The invention relates to the compounds (I) and their acids and bases salts: wherein: Formula (I) the dotted line indicates a double bond; X is N or C—R1 and Y is N or C—R2, X and Y not being simultaneously N; A is selected from the group consisting of phenyl, naphthyl and (5-11) membered monocyclic or bicyclic unsaturated cycle or heterocycle possibly substituted as defined in the application, and A can also comprise either a further (4-7) membered heterocycle, said heterocycle being a monocycle, fused, saturated or unsaturated, the polycyclic system then comprising up to 14 members and up to 5 heteroatoms selected from N, O and S; B is selected from the group of substituents as defined in the application, or B is a 4 or (6-10) membered mono or bicyclic saturated or unsaturated heterocycle containing 1-3 heteroatoms selected from N, O and S, linked by a carbon atom, and possibly substituted as defined in the application; R1 is Hydrogen or a substituent as defined in the application; R2 is Hydrogen or Halogen;
    Type: Grant
    Filed: February 24, 2015
    Date of Patent: May 28, 2019
    Assignee: MUTABILIS
    Inventors: Dmytro Atamanyuk, Francis Chevreuil, Fabien Faivre, Nicolas Lecointe, Benoît Ledoussal, Chrystelle Oliveira, Christophe Simon, Vincent Gerusz
  • Patent number: 10183943
    Abstract: The present invention relates to heterocyclic compounds, their process of preparation, pharmaceutical compositions comprising these compounds and use thereof, optionally in combination with other antibacterial agents and/or beta-lactam compounds, for the prevention or treatment of bacterial infections. The present invention also relates to the use of these compounds as ?-lactamase inhibitors and/or as antibacterial agents.
    Type: Grant
    Filed: May 6, 2016
    Date of Patent: January 22, 2019
    Assignee: MUTABILIS
    Inventors: Julien Barbion, Audrey Caravano, Sophie Chasset, Francis Chevreuil, Nicolas Lecointe, Benoît Ledoussal, Frédéric Le Strat, Sébastien Richard, Christophe Simon, Sophie Vomscheid, Julie Brias, Sophie Briet, Fabien Faivre, Géraldine Le Fralliec, Chrystelle Oliveira
  • Patent number: 10072006
    Abstract: The present invention relates to heterocyclic compounds, their process of preparation, pharmaceutical compositions comprising these compounds and use thereof, optionally in combination with other antibacterial agents and/or beta-lactam compounds, for the prevention or treatment of bacterial infections. The present invention also relates to the use of these compounds as ?-lactamase inhibitors and/or as antibacterial agents.
    Type: Grant
    Filed: March 30, 2016
    Date of Patent: September 11, 2018
    Assignee: MUTABILIS
    Inventors: Audrey Caravano, Sophie Chasset, Francis Chevreuil, Fabien Faivre, Nicolas Lecointe, Benoît Ledoussal, Frédéric Le Strat, Sébastien Richard, Christophe Simon, Sophie Vomscheid, Julie Brias, Julien Barbion
  • Publication number: 20180118765
    Abstract: The present invention relates to heterocyclic compounds, their process of preparation, pharmaceutical compositions comprising these compounds and use thereof, optionally in combination with other antibacterial agents and/or beta-lactam compounds, for the prevention or treatment of bacterial infections. The present invention also relates to the use of these compounds as ?-lactamase inhibitors and/or as antibacterial agents.
    Type: Application
    Filed: April 1, 2016
    Publication date: May 3, 2018
    Inventors: Julie Brias, Sophie Chasset, Francis Chevreuil, Nicolas Lecointe, Benoît Ledoussal, Frédéric Le Strat, Sophie Vomscheid, Sébastien Richard, Fabien Faivre, Julien Barbion, Audrey Caravano, Géraldine Le Fralliec, Christophe Simon
  • Publication number: 20180093985
    Abstract: The present invention relates to heterocyclic compounds, their process of preparation, pharmaceutical compositions comprising these compounds and use thereof, optionally in combination with other antibacterial agents and/or beta-lactam compounds, for the prevention or treatment of bacterial infections. The present invention also relates to the use of these compounds as ?-lactamase inhibitors and/or as antibacterial agents.
    Type: Application
    Filed: May 6, 2016
    Publication date: April 5, 2018
    Inventors: Julien Barbion, Audrey Caravano, Sophie Chasset, Francis Chevreuil, Nicolas Lecointe, Benoît Ledoussal, Frédéric Le Strat, Sébastien Richard, Christophe Simon, Sophie Vomscheid, Julie Brias, Sophie Briet, Fabien Faivre, Géraldine Le Fralliec, Chrystelle Oliveira
  • Publication number: 20180086761
    Abstract: The present invention relates to heterocyclic compounds, their process of preparation, pharmaceutical compositions comprising these compounds and use thereof, optionally in combination with other antibacterial agents and/or beta-lactam compounds, for the prevention or treatment of bacterial infections. The present invention also relates to the use of these compounds as ?-lactamase inhibitors and/or as antibacterial agents.
    Type: Application
    Filed: March 30, 2016
    Publication date: March 29, 2018
    Inventors: Audrey Caravano, Sophie Chasset, Francis Chevreuil, Fabien Faivre, Nicolas Lecointe, Benoît Ledoussal, Frédéric Le Strat, Sébastien Richard, Christophe Simon, Sophie Vomscheid, Julie Brias, Julien Barbion
  • Publication number: 20170015661
    Abstract: The invention relates to the compounds (I) and their acids and bases salts: wherein: Formula (I) the dotted line indicates a double bond; X is N or C—R1 and Y is N or C—R2, X and Y not being simultaneously N; A is selected from the group consisting of phenyl, naphthyl and (5-11) membered monocyclic or bicyclic unsaturated cycle or heterocycle possibly substituted as defined in the application, and A can also comprise either a further (4-7) membered heterocycle, said heterocycle being a monocycle, fused, saturated or unsaturated, the polycyclic system then comprising up to 14 members and up to 5 heteroatoms selected from N, O and S; B is selected from the group of substituents as defined in the application, or B is a 4 or (6-10) membered mono or bicyclic saturated or unsaturated heterocycle containing 1-3 heteroatoms selected from N, O and S, linked by a carbon atom, and possibly substituted as defined in the application; R1 is Hydrogen or a substituent as defined in the application; R2 is Hydrogen or Halogen;
    Type: Application
    Filed: February 24, 2015
    Publication date: January 19, 2017
    Inventors: Dmytro ATAMANYUK, Francis CHEVREUIL, Fabien FAIVRE, Nicolas LECOINTE, BenoÏ LEDOUSSAL, Chrystelle OLIVEIRA, Christophe SIMON
  • Patent number: 8984673
    Abstract: Equalizing valve (1) comprising a duct (6) having an inlet section (7) and an outlet section (8), a seat (10) and a valve element (12) able to move between a closed position and an open position, characterized in that said duct is able to admit a flow in which, for any flow line (13) between said inlet section and said outlet section, the velocity vector (15) at a given point makes an angle with the velocity vector (14) in the inlet section which increases with the distance away from the inlet section, the angle between the velocity vector (16) in the outlet section and the velocity vector in the inlet section ranging between 80° and 150°, and in which the valve element, in the closed position, makes an angle of between 0° and 70° with the normal to the outlet section.
    Type: Grant
    Filed: September 7, 2010
    Date of Patent: March 24, 2015
    Assignee: Raccords et Plastiques Nicoll
    Inventors: Jean-Pierre Serin, David Dupe, Nicolas Lecointe
  • Publication number: 20130285372
    Abstract: The present disclosure describes a device for connection, by means of an injected assembly fluid, of a first and a second pipe elements for transport of liquid or gaseous fluid, the second element having a socket receiving an end of the first element, comprising a diffusion part for diffusion of the injected assembly fluid, the diffusion part being adapted to be arranged on a circumference of the first element and against an edge of the socket, said diffusion part having at least one opening for the injection of assembly fluid into said diffusion part. The diffusion part forms a chamber for collecting said assembly fluid and for distributing it circumferentially. The device comprises directing means allowing to actively direct the assembly fluid towards a connection space between the socket and the first element.
    Type: Application
    Filed: October 25, 2011
    Publication date: October 31, 2013
    Applicant: Raccords et Plastiques Nicoll
    Inventors: Nicolas Lecointe, Michel Maudet
  • Publication number: 20120204333
    Abstract: Equalizing valve (1) comprising a duct (6) having an inlet section (7) and an outlet section (8), a seat (10) and a valve element (12) able to move between a closed position and an open position, characterized in that said duct is able to admit a flow in which, for any flow line (13) between said inlet section and said outlet section, the velocity vector (15) at a given point makes an angle with the velocity vector (14) in the inlet section which increases with the distance away from the inlet section, the angle between the velocity vector (16) in the outlet section and the velocity vector in the inlet section ranging between 80° and 150°, and in which the valve element, in the closed position, makes an angle of between 0° and 70° with the normal to the outlet section.
    Type: Application
    Filed: September 7, 2010
    Publication date: August 16, 2012
    Inventors: Jean-Pierre Serin, David Dupe, Nicolas Lecointe