Patents by Inventor Nicolas Lecointe
Nicolas Lecointe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11530227Abstract: The present invention relates to compounds of formula (I) and their use for treating or preventing a bacterial infection or as an antibacterial agent and/or as a ?-lactamase inhibitor.Type: GrantFiled: July 30, 2019Date of Patent: December 20, 2022Assignee: MUTABILISInventors: Julien Barbion, Audrey Caravano, Sophie Chasset, Francis Chevreuil, Nicolas Lecointe, Frédéric Le Strat, Chrystelle Oliveira, Christophe Simon
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Publication number: 20210277019Abstract: The present invention relates to compounds of formula (I) and their use for treating or preventing a bacterial infection or as an antibacterial agent and/or as a ?-lactamase inhibitor.Type: ApplicationFiled: July 30, 2019Publication date: September 9, 2021Inventors: Julien Barbion, Audrey Caravano, Sophie Chasset, Francis Chevreuil, Nicolas Lecointe, Frédéric Le Strat, Chrystelle Oliveira, Christophe Simon
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Patent number: 10842779Abstract: The present invention relates to heterocyclic compounds, their process of preparation, pharmaceutical compositions comprising these compounds and use thereof, optionally in combination with other antibacterial agents and/or beta-lactam compounds, for the prevention or treatment of bacterial infections. The present invention also relates to the use of these compounds as ?-lactamase inhibitors and/or as antibacterial agents.Type: GrantFiled: December 22, 2016Date of Patent: November 24, 2020Assignee: MUTABILISInventors: Julie Brias, Sophie Chasset, Francis Chevreuil, Nicolas Lecointe, Benoit Ledoussal, Frédéric Le Strat, Julien Barbion
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Patent number: 10722520Abstract: A compound of formula (I) or a racemate, an enantiomer, a diastereoisomer, a geometric isomer or a pharmaceutically acceptable salt thereof, and its use as antibacterial agent.Type: GrantFiled: September 29, 2017Date of Patent: July 28, 2020Assignee: MUTABILISInventors: Julien Barbion, Audrey Caravano, Sophie Chasset, Francis Chevreuil, Fabien Faivre, Rémi Lebel, Nicolas Lecointe, Benoît Ledoussal, Frédéric Le-Strat, Christophe Simon, Chrystelle Oliveira, Géraldine Le Fralliec, Julie Brias, Laurence Farescour, Sophie Vomscheid, Sébastien Richard
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Publication number: 20200017495Abstract: The present invention relates to compound of formula (I) and their use for treating bacterial infections.Type: ApplicationFiled: February 6, 2018Publication date: January 16, 2020Inventors: Damien Bonnard, Julie Brias, Julien Barbion, Audrey Caravano, Sophie Chasset, Francis Chevreuil, Nicolas Lecointe, Benoît Ledoussal, Erwann Le Rouzic, Frédéric Le Strat, François Moreau, Marie-Hélène Quernin, Ludovic Waeckel
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Patent number: 10501481Abstract: The present invention relates to heterocyclic compounds, their process of preparation, pharmaceutical compositions comprising these compounds and use thereof, optionally in combination with other antibacterial agents and/or beta-lactam compounds, for the prevention or treatment of bacterial infections. The present invention also relates to the use of these compounds as ?-lactamase inhibitors and/or as antibacterial agents.Type: GrantFiled: April 1, 2016Date of Patent: December 10, 2019Assignee: MUTABILISInventors: Julie Brias, Sophie Chasset, Francis Chevreuil, Nicolas Lecointe, Benôit Ledoussal, Frédéric Le Strat, Sophie Vomscheid, Sébastien Richard, Fabien Faivre, Julien Barbion, Audrey Caravano, Géraldine Le Fralliec, Christophe Simon
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Publication number: 20190224210Abstract: A compound of formula (I) or a racemate, an enantiomer, a diastereoisomer, a geometric isomer or a pharmaceutically acceptable salt thereof, and its use as antibacterial agent.Type: ApplicationFiled: September 29, 2017Publication date: July 25, 2019Inventors: Julien BARBION, Audrey CARAVANO, Sophie CHASSET, Francis CHEVREUIL, Fabien FAIVRE, Rémi LEBEL, Nicolas LECOINTE, Benoît LEDOUSSAL, Frédéric LE-STRAT, Christophe SIMON, Chrystelle OLIVEIRA, Géraldine LE FRALLIEC, Julie BRIAS, Laurence FARESCOUR, Sophie VOMSCHEID, Sébastien RICHARD
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Publication number: 20190175561Abstract: The present invention relates to heterocyclic compounds, their process of preparation, pharmaceutical compositions comprising these compounds and use thereof, optionally in combination with other antibacterial agents and/or beta-lactam compounds, for the prevention or treatment of bacterial infections. The present invention also relates to the use of these compounds as ?-lactamase inhibitors and/or as antibacterial agents.Type: ApplicationFiled: December 22, 2016Publication date: June 13, 2019Applicant: MUTABILISInventors: Julie BRIAS, Sophie CHASSET, Francis CHEVREUIL, Nicolas LECOINTE, Benoît LEDOUSSAL, Frédéric LE STRAT, Julien BARBION
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Patent number: 10301305Abstract: The invention relates to the compounds (I) and their acids and bases salts: wherein: Formula (I) the dotted line indicates a double bond; X is N or C—R1 and Y is N or C—R2, X and Y not being simultaneously N; A is selected from the group consisting of phenyl, naphthyl and (5-11) membered monocyclic or bicyclic unsaturated cycle or heterocycle possibly substituted as defined in the application, and A can also comprise either a further (4-7) membered heterocycle, said heterocycle being a monocycle, fused, saturated or unsaturated, the polycyclic system then comprising up to 14 members and up to 5 heteroatoms selected from N, O and S; B is selected from the group of substituents as defined in the application, or B is a 4 or (6-10) membered mono or bicyclic saturated or unsaturated heterocycle containing 1-3 heteroatoms selected from N, O and S, linked by a carbon atom, and possibly substituted as defined in the application; R1 is Hydrogen or a substituent as defined in the application; R2 is Hydrogen or Halogen;Type: GrantFiled: February 24, 2015Date of Patent: May 28, 2019Assignee: MUTABILISInventors: Dmytro Atamanyuk, Francis Chevreuil, Fabien Faivre, Nicolas Lecointe, Benoît Ledoussal, Chrystelle Oliveira, Christophe Simon, Vincent Gerusz
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Patent number: 10183943Abstract: The present invention relates to heterocyclic compounds, their process of preparation, pharmaceutical compositions comprising these compounds and use thereof, optionally in combination with other antibacterial agents and/or beta-lactam compounds, for the prevention or treatment of bacterial infections. The present invention also relates to the use of these compounds as ?-lactamase inhibitors and/or as antibacterial agents.Type: GrantFiled: May 6, 2016Date of Patent: January 22, 2019Assignee: MUTABILISInventors: Julien Barbion, Audrey Caravano, Sophie Chasset, Francis Chevreuil, Nicolas Lecointe, Benoît Ledoussal, Frédéric Le Strat, Sébastien Richard, Christophe Simon, Sophie Vomscheid, Julie Brias, Sophie Briet, Fabien Faivre, Géraldine Le Fralliec, Chrystelle Oliveira
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Patent number: 10072006Abstract: The present invention relates to heterocyclic compounds, their process of preparation, pharmaceutical compositions comprising these compounds and use thereof, optionally in combination with other antibacterial agents and/or beta-lactam compounds, for the prevention or treatment of bacterial infections. The present invention also relates to the use of these compounds as ?-lactamase inhibitors and/or as antibacterial agents.Type: GrantFiled: March 30, 2016Date of Patent: September 11, 2018Assignee: MUTABILISInventors: Audrey Caravano, Sophie Chasset, Francis Chevreuil, Fabien Faivre, Nicolas Lecointe, Benoît Ledoussal, Frédéric Le Strat, Sébastien Richard, Christophe Simon, Sophie Vomscheid, Julie Brias, Julien Barbion
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Publication number: 20180118765Abstract: The present invention relates to heterocyclic compounds, their process of preparation, pharmaceutical compositions comprising these compounds and use thereof, optionally in combination with other antibacterial agents and/or beta-lactam compounds, for the prevention or treatment of bacterial infections. The present invention also relates to the use of these compounds as ?-lactamase inhibitors and/or as antibacterial agents.Type: ApplicationFiled: April 1, 2016Publication date: May 3, 2018Inventors: Julie Brias, Sophie Chasset, Francis Chevreuil, Nicolas Lecointe, Benoît Ledoussal, Frédéric Le Strat, Sophie Vomscheid, Sébastien Richard, Fabien Faivre, Julien Barbion, Audrey Caravano, Géraldine Le Fralliec, Christophe Simon
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Publication number: 20180093985Abstract: The present invention relates to heterocyclic compounds, their process of preparation, pharmaceutical compositions comprising these compounds and use thereof, optionally in combination with other antibacterial agents and/or beta-lactam compounds, for the prevention or treatment of bacterial infections. The present invention also relates to the use of these compounds as ?-lactamase inhibitors and/or as antibacterial agents.Type: ApplicationFiled: May 6, 2016Publication date: April 5, 2018Inventors: Julien Barbion, Audrey Caravano, Sophie Chasset, Francis Chevreuil, Nicolas Lecointe, Benoît Ledoussal, Frédéric Le Strat, Sébastien Richard, Christophe Simon, Sophie Vomscheid, Julie Brias, Sophie Briet, Fabien Faivre, Géraldine Le Fralliec, Chrystelle Oliveira
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Publication number: 20180086761Abstract: The present invention relates to heterocyclic compounds, their process of preparation, pharmaceutical compositions comprising these compounds and use thereof, optionally in combination with other antibacterial agents and/or beta-lactam compounds, for the prevention or treatment of bacterial infections. The present invention also relates to the use of these compounds as ?-lactamase inhibitors and/or as antibacterial agents.Type: ApplicationFiled: March 30, 2016Publication date: March 29, 2018Inventors: Audrey Caravano, Sophie Chasset, Francis Chevreuil, Fabien Faivre, Nicolas Lecointe, Benoît Ledoussal, Frédéric Le Strat, Sébastien Richard, Christophe Simon, Sophie Vomscheid, Julie Brias, Julien Barbion
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Publication number: 20170015661Abstract: The invention relates to the compounds (I) and their acids and bases salts: wherein: Formula (I) the dotted line indicates a double bond; X is N or C—R1 and Y is N or C—R2, X and Y not being simultaneously N; A is selected from the group consisting of phenyl, naphthyl and (5-11) membered monocyclic or bicyclic unsaturated cycle or heterocycle possibly substituted as defined in the application, and A can also comprise either a further (4-7) membered heterocycle, said heterocycle being a monocycle, fused, saturated or unsaturated, the polycyclic system then comprising up to 14 members and up to 5 heteroatoms selected from N, O and S; B is selected from the group of substituents as defined in the application, or B is a 4 or (6-10) membered mono or bicyclic saturated or unsaturated heterocycle containing 1-3 heteroatoms selected from N, O and S, linked by a carbon atom, and possibly substituted as defined in the application; R1 is Hydrogen or a substituent as defined in the application; R2 is Hydrogen or Halogen;Type: ApplicationFiled: February 24, 2015Publication date: January 19, 2017Inventors: Dmytro ATAMANYUK, Francis CHEVREUIL, Fabien FAIVRE, Nicolas LECOINTE, BenoÏ LEDOUSSAL, Chrystelle OLIVEIRA, Christophe SIMON
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Patent number: 8984673Abstract: Equalizing valve (1) comprising a duct (6) having an inlet section (7) and an outlet section (8), a seat (10) and a valve element (12) able to move between a closed position and an open position, characterized in that said duct is able to admit a flow in which, for any flow line (13) between said inlet section and said outlet section, the velocity vector (15) at a given point makes an angle with the velocity vector (14) in the inlet section which increases with the distance away from the inlet section, the angle between the velocity vector (16) in the outlet section and the velocity vector in the inlet section ranging between 80° and 150°, and in which the valve element, in the closed position, makes an angle of between 0° and 70° with the normal to the outlet section.Type: GrantFiled: September 7, 2010Date of Patent: March 24, 2015Assignee: Raccords et Plastiques NicollInventors: Jean-Pierre Serin, David Dupe, Nicolas Lecointe
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Publication number: 20130285372Abstract: The present disclosure describes a device for connection, by means of an injected assembly fluid, of a first and a second pipe elements for transport of liquid or gaseous fluid, the second element having a socket receiving an end of the first element, comprising a diffusion part for diffusion of the injected assembly fluid, the diffusion part being adapted to be arranged on a circumference of the first element and against an edge of the socket, said diffusion part having at least one opening for the injection of assembly fluid into said diffusion part. The diffusion part forms a chamber for collecting said assembly fluid and for distributing it circumferentially. The device comprises directing means allowing to actively direct the assembly fluid towards a connection space between the socket and the first element.Type: ApplicationFiled: October 25, 2011Publication date: October 31, 2013Applicant: Raccords et Plastiques NicollInventors: Nicolas Lecointe, Michel Maudet
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Publication number: 20120204333Abstract: Equalizing valve (1) comprising a duct (6) having an inlet section (7) and an outlet section (8), a seat (10) and a valve element (12) able to move between a closed position and an open position, characterized in that said duct is able to admit a flow in which, for any flow line (13) between said inlet section and said outlet section, the velocity vector (15) at a given point makes an angle with the velocity vector (14) in the inlet section which increases with the distance away from the inlet section, the angle between the velocity vector (16) in the outlet section and the velocity vector in the inlet section ranging between 80° and 150°, and in which the valve element, in the closed position, makes an angle of between 0° and 70° with the normal to the outlet section.Type: ApplicationFiled: September 7, 2010Publication date: August 16, 2012Inventors: Jean-Pierre Serin, David Dupe, Nicolas Lecointe