Patents by Inventor Nicolas MERIENNE

Nicolas MERIENNE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GENOME EDITING FOR THE TREATMENT OF HUNTINGTON'S DISEASE
    Publication number: 20170224843
    Abstract: A treatment of Huntington's disease (HD) using the Clustered-Regularly Interspaced Short Palindromic Repeats (CRISPR) system. This technology offers the possibility to design a small RNA (sgRNA), which is incorporated into a CRISPR-associated protein (Cas9) to recognize and induce DNA double-strand breaks at a specific target location. In the context of HD, this allows to block the expression of the mutant huntingtin or repair the CAG expansion causing the disease.
    Type: Application
    Filed: August 4, 2015
    Publication date: August 10, 2017
    Applicant: CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS (CHUV)
    Inventors: Nicole DEGLON, Nicolas MERIENNE