Patents by Inventor Nicolas Newton

Nicolas Newton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100159452
    Abstract: The invention relates to a method for detecting a target nucleic acid in a sample using fluorescent probe pairs which include fluorescent reporter and quencher molecules which may be used in hybridization assays and in nucleic acid amplification reactions, especially polymerase chain reactions (PCR).
    Type: Application
    Filed: December 22, 2008
    Publication date: June 24, 2010
    Applicant: ROCHE MOLECULAR SYSTEMS, INC.
    Inventor: Nicolas Newton
  • Publication number: 20100143901
    Abstract: The invention is a method for amplification and detection of nucleic acids using primers and at least one hybridization probe labeled with a first fluorescent moiety and a second moiety, capable of changing the fluorescence of said first fluorescent moiety. The method comprises the steps of effecting denaturation of said target, formation of hybrids between said primers and probe and said target and detecting the change in fluorescence of said first fluorescent moiety, upon formation of said hybrids. Reaction mixtures and kits for practicing the method of the present invention are also disclosed.
    Type: Application
    Filed: December 9, 2008
    Publication date: June 10, 2010
    Applicant: ROCHE MOLECULAR SYSTEMS, INC.
    Inventor: Nicolas Newton
  • Publication number: 20100099110
    Abstract: The present invention includes a method of allele-specific amplification, utilizing an allele-specific oligonucleotide, at least partially complementary to more than one variant of the target sequence, but having a 3?-terminal nucleotide complementary to only one variant of the target sequence and having at least one nucleotide with a base covalently modified at the exocyclic amino group, wherein the allele-specific oligonucleotide is extended by a nucleotide-incorporating biocatalyst predominantly when hybridized to the variant of the target sequence for which it has said complementary 3?-terminal nucleotide.
    Type: Application
    Filed: October 20, 2009
    Publication date: April 22, 2010
    Applicant: ROCHE MOLECULAR SYSTEMS, INC.
    Inventors: Stephen G. Will, Alison Tsan, Nicolas Newton
  • Publication number: 20090053720
    Abstract: Methods and compositions for amplification of a target sequence by suppressing amplification of related sequences are provided.
    Type: Application
    Filed: August 5, 2008
    Publication date: February 26, 2009
    Applicant: Roche Molecular Systems, Inc.
    Inventor: Nicolas Newton