Abstract: The invention relates to the use of various extracts of the Nephelium lappaceum plant for increasing the firmness and/or elasticity of the skin and/or mucous membranes, by increasing type I and/or type V collagen and/or LOX-L, fibulin-5, emiline-1 and/or fibrillin-1 gene and/or protein expression, and/or by decreasing CYR61 expression, in the skin and mucous membranes. Another subject of the invention relates to the use of said extracts in a cosmetic composition comprising at least one cosmetically acceptable excipient. Another subject further relates to a cosmetic care method comprising the application of the extract according to the invention or of a cosmetic composition comprising it, for increasing the firmness and/or elasticity of the skin and/or mucous membranes, by increasing type I and/or type V collagen, fibrillin-1 and/or LOX-L, fibulin-5, emiline-1 and/or fibrillin-1 gene and/or protein expression, and/or by decreasing CYR61 expression, in the skin and mucous membranes.

Abstract: Novel cosmetic and dermatological uses of an extract of Cistus monspeliensis The invention relates to the non-therapeutic cosmetic use of an extract of Cistus monspeliensis for increasing and/or maintaining tissue homeostasis in the skin and/or the mucous membranes and/or the skin appendages, by increasing and/or maintaining the barrier function and/or cell differentiation in the skin and/or the mucous membranes and/or the skin appendages. Another subject relates to a non-therapeutic cosmetic care process notably comprising the topical application of the extract of C. monspeliensis or of a cosmetic composition comprising same. Yet another subject relates to the extract of C. monspeliensis, for its use for preventing and/or treating diseases induced by a decrease in the gene and/or protein expression of ECM1, advantageously lichen sclerosus or lipoid proteinosis, and/or for preventing and/or treating scars.

Abstract: The invention relates to the use of an extract of the fungus Inonotus obliquus for maintaining and/or increasing the cohesion of the skin tissues, for preventing the appearance of and/or for reducing shadows and/or bags in the area around the eyes, for maintaining and/or increasing the radiance and/or homogeneity of the skin complexion and/or for maintaining and/or increasing the barrier function of the skin and/or for increasing the skin microcirculation. The invention also relates to the extract of I. obliquus or a dermatological composition comprising same, for its use for reducing ruddiness and/or for preventing and/or reducing pathologies resulting from a reduction in the cohesion of the skin tissues, notably itching and/or couperosis.

Abstract: The present invention relates to the cosmetic use of a Bixa orellana extract for preventing and/or reducing sebum secretion and/or for preventing and/or reducing the unaesthetic and/or unpleasant and/or uncomfortable manifestations of sebum secretion. It also relates to a cosmetic care method, characterized in that it comprises the topical application to at least one area of skin, advantageously of the scalp, of a Bixa orellana extract for preventing and/or reducing sebum secretion and/or for preventing and/or reducing the unaesthetic and/or unpleasant and/or uncomfortable manifestations of sebum secretion. Finally, it relates to a Bixa orellana extract for use in the treatment and/or prevention of a pathological condition associated with sebum hyperproduction chosen from pathological hyperseborrhoea and seborrhoeic eczema and/or any combination thereof.

Abstract: The invention relates to in vitro or ex vivo methods for assessing the cognitive function of a subject in the context of the prevention of neurodegenerative diseases. A particular method comprises a step of associating a subject to a cognitive status selected from healthy cognitive status, Subjective Cognitive Impairment, Mild Cognitive Impairment and neurodegenerative disease, and the association of cognitive status results from the evaluation of glycosylated MCSF and CCR2 expressed at the surface of PBMC in a biological sample from the subject. The present invention also provides kits suitable for implementing such methods.

Abstract: The invention relates to the use of various extracts of the Nephelium lappaceum plant for increasing the firmness and/or elasticity of the skin and/or mucous membranes, by increasing type I and/or type V collagen and/or LOX-L, fibulin-5, emiline-1 and/or fibrillin-1 gene and/or protein expression, and/or by decreasing CYR61 expression, in the skin and mucous membranes. Another subject of the invention relates to the use of said extracts in a cosmetic composition comprising at least one cosmetically acceptable excipient. Another subject further relates to a cosmetic care method comprising the application of the extract according to the invention or of a cosmetic composition comprising it, for increasing the firmness and/or elasticity of the skin and/or mucous membranes, by increasing type I and/or type V collagen, fibrillin-1 and/or LOX-L, fibulin-5, emiline-1 and/or fibrillin-1 gene and/or protein expression, and/or by decreasing CYR61 expression, in the skin and mucous membranes.

Abstract: The invention relates to in vitro or ex vivo methods for assessing the cognitive function of a subject in the context of the prevention of neurodegenerative diseases. A particular method comprises a step of associating a subject to a cognitive status selected from healthy cognitive status, Subjective Cognitive Impairment, Mild Cognitive Impairment and neurodegenerative disease, and the association of cognitive status results from the evaluation of glycosylated MCSF and CCR2 expressed at the surface of PBMC in a biological sample from the subject. The present invention also provides kits suitable for implementing such methods.

Abstract: The present disclosure generally relates to the fields of genetics and diagnostic medicine. The invention more specifically relates to in vitro or ex vivo methods for assessing the cognitive function of a subject in the context of the prevention of neurodegenerative diseases. A particular method comprises a step of associating a subject to a cognitive status selected from healthy cognitive status, Subjective Cognitive Impairment, Mild Cognitive Impairment and neurodegenerative disease, wherein said association results from the evaluation of glycosylated MCSF and CCR2 expressed at the surface of PBMC in a biological sample from the subject. The present invention also provides kits suitable for implementing such methods.

Abstract: Novel monopropellants are provided. The monopropellants are based on N2O, to their preparation method and their uses for space propulsion.

Abstract: Described herein are systems and methods for indexing documents during CPU idle time. The method can include the steps of determining at regular intervals if CPU usage is above a threshold value and pausing the indexing when CPU usage rises above a threshold value. If the CPU usage is below a threshold value the indexing is continued. Unlike traditional document systems, the document database described herein can be updated without interrupting the use of the computer.

Abstract: Described herein are systems and methods for indexing documents in a quasi real-time manner. The method can include the steps of indexing documents and storing document information in a database, registering with an extended MAPI layer of an e-mail program for notification of changes to the documents, and responding to received notification of changes by updating the database to reflect the addition, modification, and/or deletion of documents. Unlike traditional document systems, the document index described herein can be updated without rescanning all the indexed documents.