Patents by Inventor Nicolas Phillip James Brindle

Nicolas Phillip James Brindle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleic acid encoding angiopoietin-2 specific Tie2 receptor
    Patent number: 10882895
    Abstract: In one aspect, provided herein is a polypeptide comprising a modified angiopoietin receptor or fragment thereof, wherein the polypeptide binds preferentially to angiopoietin-2 compared to angiopoeitin-1. Nucleic acid sequences encoding the polypeptide, as well as pharmaceutical uses of the polypeptide in treating diseases such as cancer and inflammation are also provided.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: January 5, 2021
    Assignee: UNITED KINGDOM RESEARCH AND INNOVATION
    Inventors: Nicolas Phillip James Brindle, Julian Edward Sale
  • ANGIOPOIETIN-2 SPECIFIC TIE2 RECEPTOR
    Publication number: 20190218273
    Abstract: In one aspect, provided herein is a polypeptide comprising a modified angiopoietin receptor or fragment thereof, wherein the polypeptide binds preferentially to angiopoietin-2 compared to angiopoeitin-1. Nucleic acid sequences encoding the polypeptide, as well as pharmaceutical uses of the polypeptide in treating diseases such as cancer and inflammation are also provided.
    Type: Application
    Filed: December 21, 2018
    Publication date: July 18, 2019
    Inventors: Nicolas Phillip James Brindle, Julian Edward Sale
  • Angiopoietin-2 specific TIE2 receptor
    Patent number: 10208100
    Abstract: In one aspect, provided herein is a polypeptide comprising a modified angiopoietin receptor or fragment thereof, wherein the polypeptide binds preferentially to angiopoietin-2 compared to angiopoietin-1. Nucleic acid sequences encoding the polypeptide, as well as pharmaceutical uses of the polypeptide in treating diseases such as cancer and inflammation are also provided.
    Type: Grant
    Filed: December 20, 2013
    Date of Patent: February 19, 2019
    Assignee: UNITED KINGDOM RESEARCH AND INNOVATION
    Inventors: Nicolas Phillip James Brindle, Julian Edward Sale
  • ANGIOPOIETIN-2 SPECIFIC TIE2 RECEPTOR
    Publication number: 20150322414
    Abstract: In one aspect, provided herein is a polypeptide comprising a modified angiopoietin receptor or fragment thereof, wherein the polypeptide binds preferentially to angiopoietin-2 compared to angiopoietin-1. Nucleic acid sequences encoding the polypeptide, as well as pharmaceutical uses of the polypeptide in treating diseases such as cancer and inflammation are also provided.
    Type: Application
    Filed: December 20, 2013
    Publication date: November 12, 2015
    Inventors: Nicolas Phillip James Brindle, Julian Edward Sale