Abstract: An automated system for preparing, detecting and analyzing a first fluid sample containing biological species, the preparation, detection and analysis system including at least one fluidic cartridge that includes at least one fluidic concentration and lysis module and one fluidic detection module including an array of several amplification chambers arranged in parallel, an apparatus including a mechanical assembly comprising at least one movable rod fastened to the frame and comprising a free end arranged to cooperate with a flexible membrane of the fluidic concentration and lysis module, an optical measurement system for measuring fluorescence through one or more amplification chambers of the fluidic detection module of the cartridge, a control and processing unit.

Abstract: An active method for decanting the dispersed phase in the continuous phase of an emulsion. According to the method, repulsive forces created by an electric field are used on the drops constituting the dispersed phase. The electric field scans the reservoir containing the emulsion, enabling the dispersed phase to be concentrated in a determined region of the reservoir, for the recovery and/or analysis of the emulsion. A device implements the method.

Abstract: A device for detecting elements in a fluid environment includes at least one acoustic resonator having a surface designed for fixing of elements. The resonator is configured for generating and measuring Lamb waves fostering generation of symmetrical Lamb waves. The device analyzes the resonance frequency of the resonator to determine the variation of the resonance frequency of the symmetrical Lamb waves representative of the presence of the elements.

Abstract: A microfluidic device for extraction of analytes of interest from a carrier liquid in a liquid solvent, the two liquids forming an interface between micro-pillars in an extraction chamber. The carrier liquid forms a wetting angle ?1 on the micro-pillars and a bottom wall of the extraction chamber, and a wetting angle ?2 on a top wall, the wetting angles satisfying equation 45°?(?1+?2)/2?135°.

Abstract: A microfluidic system including: a substrate, one surface of which is covered with electrodes configured to move, under effect of an electric field, microdrops of a liquid phase including at least one functionalized ionic liquid; and capillaries for introducing a liquid extraction fluid onto the surface and for extracting the liquid extraction fluid from an orifice by forced convection, to obtain an extraction bath located on the surface for extraction of at least one chemical or biological compound from the liquid phase, and the bath is open to a surrounding space on at least two of its opposite sides, for moving, in contact with the surface, the microdrop upstream and downstream of the bath.

Abstract: A microfluidic component comprises at least one channel (2) delineated by a top wall (6) and a bottom wall (3) and two opposite side walls (4, 5). The distance (P) between the top wall (6) and the bottom wall (3) of the channel (2) is greater than or equal to 25 micrometers and first and second sets of nanotubes (9a, 9b) are respectively borne by the two opposite side walls (4, 5) for the component to present a particularly high ratio between the contact surface and the available volume and a limited overall surface size. In addition, the distance between the two opposite side walls (4, 5) is about a few micrometers and preferably comprised between 3 and 5 micrometers.

Abstract: A method of transferring mass of at least one solute between a liquid first phase and a fluid second phase that is immiscible with the first phase, the method comprising moving at least one droplet of said liquid first phase in a microfluidic device by using electric-type forces (electrowetting or dielectrophoresis) within a space that is filled with said fluid second phase. Said droplet is preferably moved by said electric-type forces along a path between a point for injecting said droplet into said microfluidic device, and an extraction and/or analysis zone, said path being defined in such a manner that said droplet sweeps through a significant fraction of said space filled with said fluid second phase. The method may include a step of transferring said droplet using said electric-type forces to a chemical analysis device integrated in said microfluidic device, and a step of chemically analyzing said droplet. The invention also provides a device for implementing such a method.

Abstract: A method for extracting at least one chemical or biological compound from a liquid phase including at least one functionalized ionic liquid, via a liquid extracting fluid that is miscible with the ionic liquid, and a microfluidic system implementing the method. The extraction method includes moving, on one surface of a microfluidic system, at least one microdrop of the liquid phase into an extraction solution that includes the extracting fluid and that is localized on the surface to obtain in output of the solution, under effect of an electric field, an extract moving away from the surface that is rich in extracting fluid and enriched in the at least one compound, and a raffinate moving on the surface that is rich in ionic liquid and deleted in the at least one compound.

Abstract: The device for detecting elements in a fluidic medium comprises at least one acoustic resonator having a surface intended for fixing the elements. The resonator includes means for generating and measuring Lamb waves, favouring the generation of symmetrical Lamb waves. The device analyses the resonant frequency of the resonator in order to determine the variation in the resonant frequency of the symmetrical Lamb waves representative of the presence of the elements.

Abstract: A method for extracting at least one chemical or biological compound from a liquid phase including at least one functionalized ionic liquid, via a liquid extracting fluid that is miscible with the ionic liquid, and a microfluidic system implementing the method. The extraction method includes moving, on one surface of a microfluidic system, at least one microdrop of the liquid phase into an extraction solution that includes the extracting fluid and that is localized on the surface to obtain in output of the solution, under effect of an electric field, an extract moving away from the surface that is rich in extracting fluid and enriched in the at least one compound, and a raffinate moving on the surface that is rich in ionic liquid and deleted in the at least one compound.

Abstract: A lab-on-a-chip comprising a support plate, at least one fluidic network formed in a fluidic plate bonded onto the support plate, and a cover plate bonded onto the fluidic plate and covering the fluidic network. The fluidic network, at a first end, is connected to an inlet orifice allowing entry of a liquid to be sprayed and, at a second end, to a first end of an outlet channel for the liquid to be sprayed, formed in the fluidic plate. The fluidic plate is extended by a pointed electrospray nozzle at which the second end of the outlet channel forms the electrospray outlet of the lab-on-a-chip. The cover plate has a pointed extension forming a roof for that part of the channel located in the electrospray nozzle.

Abstract: The microfluidic device comprises at least one microchannel bounded by a bottom wall, side walls and a top wall and which is designed to contain at least one liquid and at least one fluid non-miscible with the liquid. The microfluidic device comprises means for stabilizing the interface between the liquid and the fluid. The means for stabilizing comprise at least one electrode arranged on at least one part of a first wall of the microchannel, over the entire length thereof, and at least one counter-electrode arranged over the entire length of the microchannel, on at least one part of a second wall, arranged facing the electrode. The electrode and counter-electrode are preferably respectively arranged on the bottom and top wall of the microchannel.

Abstract: A microfluidic component comprises at least one channel (2) delineated by a top wall (6) and a bottom wall (3) and two opposite side walls (4, 5). The distance (P) between the top wall (6) and the bottom wall (3) of the channel (2) is greater than or equal to 25 micrometers and first and second sets of nanotubes (9a, 9b) are respectively borne by the two opposite side walls (4, 5) for the component to present a particularly high ratio between the contact surface and the available volume and a limited overall surface size. In addition, the distance between the two opposite side walls (4, 5) is about a few micrometers and preferably comprised between 3 and 5 micrometers.

Abstract: A microfluidic device including a microfluidic chip assembled to an electrospray structure. The microfluidic chip includes at least one microfluidic channel leading through an outlet aperture to a surface area of the microfluidic chip. The electrospray structure includes at least one thin, planar point provided with a capillary slot that terminates at the end of the point so as to form an aperture for ejection of a liquid to be sprayed. The electrospray structure is arranged on the surface area of the microfluidic chip so that the point is cantilivered with respect to the microfluidic chip and so that the outlet aperture of the microfluidic device leads to the capillary slot of the point, which microfluidic device also has a mechanism to apply an electrospray voltage to the liquid to be sprayed.

Abstract: (EN) The invention concerns a method for extracting at least one chemical or biological compound from a liquid phase comprising at least one functionalized ionic liquid, via a liquid extracting fluid (F) which is miscible with said ionic liquid(s), and a microfluidic system (10) for implementing said method. The inventive extraction method includes moving, on one surface (12) of a microfluidic system (19), at least one microdrop (14) of said liquid phase into an extraction solution (20) which comprises said extracting fluid and which is localized on said surface to obtain in output of said solution, under the effect of an electric field, an extract (E) moving away from said surface which is rich in extracting fluid and enriched in said or at least one of said compound(s), and a raffinate (R) moving on said surface which is rich in ionic liquid(s) and deleted in said or one of said compound(s).

Abstract: The invention concerns the performing, in continuous flow, of a biological, chemical or biochemical protocol on substances to be analysed, comprising several steps which consists in: in causing a mobile analysis support (11) comprising means (12) for receiving substances to be analysed and reagents to move past; implementing the steps of the protocol on the substances as the mobile analysis support (11) moves past.

Abstract: An active method for decanting the dispersed phase in the continuous phase of an emulsion. According to the method, repulsive forces created by an electric field are used on the drops constituting the dispersed phase. The electric field scans the reservoir containing the emulsion, enabling the dispersed phase to be concentrated in a determined region of the reservoir, for the recovery and/or analysis of the emulsion. A device implements the method.

Abstract: The invention relates to a device (1) for distribution of at least one liquid product, the device comprising at least one injection tube (2) supplied by a liquid product and being provided with an outlet orifice (4) capable of cooperating with an inlet orifice (12) of a reception tube (10) for reception of each liquid product. According to the invention, the outlet orifice (4) of each injection tube (2) and the inlet orifice (12) of the reception tube (10) open up into a sealed reservoir (6) full of an immiscible liquid (8), the outlet orifice (4) of each injection tube (2) being at a spacing from the inlet orifice (12) of the reception tube (10) and able to be located close to the reception tube (12), the device (1) also comprising means (14) for pressurizing the immiscible liquid (8).

Abstract: The invention relates to an on-chip laboratory comprising a fluidic network made in a substrate, a fluid inlet orifice connected to the fluidic network and a fluid outlet orifice connected to the fluidic network. The substrate comprises a planar layer (53) in which the fluidic network and an electronebulization nozzle (65) are made, the electronebulization nozzle overhanging relatively to the remainder of the substrate (51, 52) and comprising a channel (64), one end of which is connected to the fluidic network and the other end of which forms said fluid outlet orifice, the channel being fitted with electrical conduction means (59) forming at least one electrode.

Abstract: A microfluidic device including a microfluidic chip assembled to an electrospray structure. The microfluidic chip includes at least one microfluidic channel leading through an outlet aperture to a surface area of the microfluidic chip. The electrospray structure includes at least one thin, planar point provided with a capillary slot that terminates at the end of the point so as to form an aperture for ejection of a liquid to be sprayed. The electrospray structure is arranged on the surface area of the microfluidic chip so that the point is cantilivered with respect to the microfluidic chip and so that the outlet aperture of the microfluidic device leads to the capillary slot of the point, which microfluidic device also has a mechanism to apply an electrospray voltage to the liquid to be sprayed.