Patents by Inventor Nicolas Sergeant

Nicolas Sergeant has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • POLYAMINO BIARYL COMPOUNDS AND THEIR USE
    Publication number: 20210230131
    Abstract: The present invention is directed to novel compounds of Formula I and pharmaceutically acceptable salts or solvates thereof, and their use.
    Type: Application
    Filed: July 10, 2019
    Publication date: July 29, 2021
    Inventors: Patricia MELNYK, Marie TAUTOU, Caroline EVRARD, Florian DESCAMPS, Jamal EL BALKALI, Marion GAY, Nicolas RENAULT, Nicolas SERGEANT, Pascal CARATO, Valérie VINGTDEUX
  • TREATMENT OF MYOTONIC DYSTROPHY
    Publication number: 20210024597
    Abstract: The present invention relates to compositions and methods for treating myotonic dystrophy.
    Type: Application
    Filed: September 30, 2020
    Publication date: January 28, 2021
    Inventors: DENIS FURLING, NICOLAS SERGEANT, MARIE-LAURE CAILLET-BOUDIN, LUDOVIC ARANDEL
  • NOVEL 1,4-BIS(3-AMINOPROPYL)PIPERAZINE DERIVATIVE AND ITS USE
    Publication number: 20200407325
    Abstract: The present invention relates to the compound having Formula (I) or pharmaceutically acceptable salts or solvates thereof, and its use in treating and/or preventing a Tauopathy.
    Type: Application
    Filed: September 14, 2020
    Publication date: December 31, 2020
    Inventors: Nicolas SERGEANT, Luc BUEE, Patricia MELNYK, Marion GAY, Nicolas LE FUR
  • 1,4-bis(3-aminopropyl)piperazine derivative and its use
    Patent number: 10807958
    Abstract: The present invention relates to the compound having Formula (I) or pharmaceutically acceptable salts or solvates thereof, and its use in treating and/or preventing a Tauopathy.
    Type: Grant
    Filed: June 15, 2018
    Date of Patent: October 20, 2020
    Assignees: INSERM (Institut National de la Sante et de la Recherche Medicale), UNIVERSITE DE LILLE 2 DROIT ET SANTE
    Inventors: Nicolas Sergeant, Luc Buee, Patricia Melnyk, Marion Gay, Nicolas Le Fur
  • Treatment of myotonic dystrophy
    Patent number: 10799556
    Abstract: The present invention relates to compositions and methods for treating myotonic dystrophy.
    Type: Grant
    Filed: April 14, 2015
    Date of Patent: October 13, 2020
    Assignees: ASSOCIATION INSTITUT DE MYOLOGIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
    Inventors: Denis Furling, Nicolas Sergeant, Marie-Laure Caillet-Boudin, Ludovic Arandel
  • Sulphate salts of N-(3-(4-(3-(diisobutylamino)propyl)piperazin-1-yl)propyl)-1H-benzo[d]imidazol-2-amine, preparation thereof and use of the same
    Patent number: 10772884
    Abstract: The present invention relates to sulphate salts of N-(3-(4-(3-(diisobutylamino)propyl)piperazin-1-yl)propyl)-1H-benzo[d]imidazol-2-amine and pharmaceutically acceptable solvates thereof, preparation thereof, pharmaceutical compositions containing them and use of the same in the treatment and/or prevention of neurodegenerative diseases.
    Type: Grant
    Filed: August 27, 2019
    Date of Patent: September 15, 2020
    Assignees: Alzprotect, Universite De Lille 2 Droit Et Sante, INSERM (Institut National De La Sante Et De La Recherche)
    Inventors: Stéphane Burlet, Cécilia Estrella, Mathieu Barrier, Patricia Melnyk, Nicolas Sergeant, Luc Buee, Philippe Verwaerde
  • Sulphate salts of N-(3-(4-(3-(diisobutylamino)propyl)piperazin-1-yl)propyl)-1H-benzo[d]imidazol-2-amine, preparation thereof and use of the same
    Patent number: 10537569
    Abstract: The present invention relates to sulphate salts of N-(3-(4-(3-(diisobutylamino)propyl)piperazin-1-yl)propyl)-1H-benzo[d]imidazol-2-amine and pharmaceutically acceptable solvates thereof, preparation thereof, pharmaceutical compositions containing them and use of the same in the treatment and/or prevention of neurodegenerative diseases.
    Type: Grant
    Filed: December 22, 2016
    Date of Patent: January 21, 2020
    Assignees: ALZPROTECT, Universite de Lille 2 Droit et Saute, Inserm (Institut National De La Saute et de la Recherche Medicale
    Inventors: Stéphane Burlet, Cécilia Estrella, Mathieu Barrier, Patricia Melnyk, Nicolas Sergeant, Luc Buee, Philippe Verwaerde
  • SULPHATE SALTS OF N-(3-(4-(3-(DIISOBUTYLAMINO)PROPYL)PIPERAZIN-1-YL)PROPYL)-1H-BENZO[d]IMIDAZOL-2-AMINE, PREPARATION THEREOF AND USE OF THE SAME
    Publication number: 20190381036
    Abstract: The present invention relates to sulphate salts of N-(3-(4-(3-(diisobutylamino)propyl)piperazin-1-yl)propyl)-1H-benzo[d]imidazol-2-amine and pharmaceutically acceptable solvates thereof, preparation thereof, pharmaceutical compositions containing them and use of the same in the treatment and/or prevention of neurodegenerative diseases.
    Type: Application
    Filed: August 27, 2019
    Publication date: December 19, 2019
    Inventors: Stéphane BURLET, Cécilia ESTRELLA, Mathieu BARRIER, Patricia MELNYK, Nicolas SERGEANT, Luc BUEE, Philippe VERWAERDE
  • NOVEL 1,4-BIS(3-AMINOPROPYL)PIPERAZINE DERIVATIVE AND ITS USE
    Publication number: 20180290981
    Abstract: The present invention relates to the compound having Formula (I) or pharmaceutically acceptable salts or solvates thereof, and its use in treating and/or preventing a Tauopathy.
    Type: Application
    Filed: June 15, 2018
    Publication date: October 11, 2018
    Inventors: Nicolas SERGEANT, Luc BUEE, Patricia MELNYK, Marion GAY, Nicolas LE FUR
  • 1,4-bis(3-aminopropyl)piperazine derivative and its use
    Patent number: 10017476
    Abstract: The present invention relates to the compound having Formula (I) or pharmaceutically acceptable salts or solvates thereof, and its use in treating and/or preventing a Tauopathy.
    Type: Grant
    Filed: March 16, 2016
    Date of Patent: July 10, 2018
    Assignees: INSERM (Institut National de la Sante et de la Recherche Medicale), CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU), UNIVERSITE DE LILLE 2 DROIT ET SANTE
    Inventors: Nicolas Sergeant, Luc Buee, Patricia Melnyk, Marion Gay, Nicolas Le Fur
  • NOVEL 1,4-BIS(3-AMINOPROPYL)PIPERAZINE DERIVATIVE AND ITS USE
    Publication number: 20180072679
    Abstract: The present invention relates to the compound having Formula (I) or pharmaceutically acceptable salts or solvates thereof, and its use in treating and/or preventing a Tauopathy.
    Type: Application
    Filed: March 16, 2016
    Publication date: March 15, 2018
    Applicants: INSERM ( Institut National de la Sante et de la Recherche Medicale), CENTER HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU), UNIVERSITE DE LILLE 2 DROIT ET SANTE
    Inventors: Nicolas SERGEANT, Luc BUEE, Patricia MELNYK, Marion GAY, Nicolas LE FUR
  • Methods for determining human sperm quality
    Patent number: 9759728
    Abstract: The present invention relates generally to the fields of reproductive medicine. More specifically, the present invention relates to methods and kits for determining the human sperm quality.
    Type: Grant
    Filed: September 4, 2014
    Date of Patent: September 12, 2017
    Assignees: Institut National de la Sante et de la Recherche Medicale (INSERM), Universite de Droit et de la Sante de Lille 2, Centre Hospitalier Regional Universitaire de Lille
    Inventors: Nicolas Sergeant, Valerie Mitchell, Fanny Jumeau, Julien Sigala
  • Carboline compounds usable in the treatment of neurodegenerative diseases
    Patent number: 9714245
    Abstract: The present invention relates to a compound according to Formula (A) or a pharmaceutically acceptable salt, solvate, clathrate, hydrate or polymorph thereof, and its use.
    Type: Grant
    Filed: June 27, 2014
    Date of Patent: July 25, 2017
    Assignees: ALZPROTECT, UNIVERSITE DE LILLE 2 DROIT ET SANTE, INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)
    Inventors: Patricia Melnyk, Pascal Carato, Stephane Burlet, Emilie Nguyen, Philippe Verwaerde, Nicolas Sergeant, Cecilia Estrella
  • SULPHATE SALTS OF N-(3-(4-(3-(DIISOBUTYLAMINO)PROPYL)PIPERAZIN-1-YL)PROPYL)-1H-BENZO[d]IMIDAZOL-2-AMINE, PREPARATION THEREOF AND USE OF THE SAME
    Publication number: 20170151235
    Abstract: The present invention relates to sulphate salts of N-(3-(4-(3-(diisobutylamino)propyl)piperazin-1-yl)propyl)-1H-benzo[d]imidazol-2-amine and pharmaceutically acceptable solvates thereof, preparation thereof, pharmaceutical compositions containing them and use of the same in the treatment and/or prevention of neurodegenerative diseases.
    Type: Application
    Filed: December 22, 2016
    Publication date: June 1, 2017
    Inventors: Stéphane BURLET, Cécilia ESTRELLA, Mathieu BARRIER, Patricia MELNYK, Nicolas SERGEANT, Luc BUEE, Philippe VERWAERDE
  • TREATMENT OF MYOTONIC DYSTROPHY
    Publication number: 20170035841
    Abstract: The present invention relates to compositions and methods for treating myotonic dystrophy.
    Type: Application
    Filed: April 14, 2015
    Publication date: February 9, 2017
    Inventors: DENIS FURLING, NICOLAS SERGEANT, MARIE-LAURE CAILLET-BOUDIN, LUDOVIC ARANDEL
  • Sulphate salts of N-(3-(4-(3-(diisobutylamino)propyl)piperazin-1-yl)propyl)-1H-benzo[d]imidazol-2-amine, preparation thereof and use of the same
    Patent number: 9562018
    Abstract: The present invention relates to sulphate salts of N-(3-(4-(3-(diisobutylamino)propyl)piperazin-1-yl)propyl)-1H-benzo[d]imidazol-2-amine and pharmaceutically acceptable solvates thereof, preparation thereof, pharmaceutical compositions containing them and use of the same in the treatment and/or prevention of neurodegenerative diseases.
    Type: Grant
    Filed: December 27, 2013
    Date of Patent: February 7, 2017
    Assignee: Alzprotect
    Inventors: Stéphane Burlet, Cécilia Estrella, Mathieu Barrier, Patricia Melnyk, Nicolas Sergeant, Luc Buee, Philippe Verwaerde
  • METHODS FOR DETERMINING HUMAN SPERM QUALITY
    Publication number: 20160356785
    Abstract: The present invention relates generally to the fields of reproductive medicine. More specifically, the present invention relates to methods and kits for determining the human sperm quality.
    Type: Application
    Filed: September 4, 2014
    Publication date: December 8, 2016
    Inventors: Nicolas SERGEANT, Valérie MITCHELL, Fanny JUMEAU, Julien SIGALA
  • Carboline Compounds Usable in The Treatment of Neurodegenerative Diseases
    Publication number: 20160152610
    Abstract: The present invention relates to a compound according to Formula (A) or a pharmaceutically acceptable salt, solvate, clathrate, hydrate or polymorph thereof, and its use.
    Type: Application
    Filed: June 27, 2014
    Publication date: June 2, 2016
    Inventors: Patricia MELNYK, Pascal CARATO, Stephane BURLET, Emilie NGUYEN, Philippe VERWAERDE, Nicolas SERGEANT, Cecilia ESTRELLA
  • SULPHATE SALTS OF N-(3-(4-(3-(DIISOBUTYLAMINO)PROPYL)PIPERAZIN-1-YL)PROPYL)-1H-BENZO[d]IMIDAZOL-2-AMINE, PREPARATION THEREOF AND USE OF THE SAME
    Publication number: 20160108003
    Abstract: The present invention relates to sulphate salts of N-(3-(4-(3-(diisobutylamino)propyl)piperazin-1-yl)propyl)-1H-benzo[d]imidazol-2-amine and pharmaceutically acceptable solvates thereof, preparation thereof, pharmaceutical compositions containing them and use of the same in the treatment and/or prevention of neurodegenerative diseases.
    Type: Application
    Filed: December 27, 2013
    Publication date: April 21, 2016
    Applicant: Alzproject
    Inventors: Stéphane BURLET, Cécilia ESTRELLA, Mathieu BARRIER, Patricia MELNYK, Nicolas SERGEANT, Luc BUEE, Philippe VERWAERDE
  • Use of 1,4-bis (3-aminoalkyl) piperazine derivatives in the treatment of neurodegenerative diseases
    Patent number: 9044478
    Abstract: Use of 1,4-bis(3-aminoalkyl)piperazine derivatives as defined in formula I or II for the manufacture of a pharmaceutical composition intended for the treatment of neurodegenerative diseases, related neurodegenerative diseases, developmental diseases or cancer. The instant invention is also directed to some specific 1,4-bis(3-aminoalkyl)piperazine derivatives and pharmaceutical composition including them.
    Type: Grant
    Filed: November 8, 2005
    Date of Patent: June 2, 2015
    Assignees: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE, UNIVERSITE DU DROIT ET DE LA SANTA-LILLE II
    Inventors: Nicolas Sergeant, Andre Delacourte, Patricia Melnyk, Luc Buee