Patents by Inventor Nicolas Verbrugge

Nicolas Verbrugge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • REACTIONS OF RADIOACTIVE COMPOUNDS FACILITATED BY A SOLID PHASE
    Publication number: 20230382855
    Abstract: The current invention provides a method for performing chemical reactions of radioactive compounds, and a device, system and method for improved heating for chemical reactions.
    Type: Application
    Filed: March 10, 2023
    Publication date: November 30, 2023
    Inventors: Navarro LAURENT, Nicolas VERBRUGGE, Matthias D'HUYVETTER, Matthias FRIEBE, Vincent TADINO, Nicolas MAINDRON, Yoann JOYARD
  • Fluoride trapping arrangement
    Patent number: 10703771
    Abstract: The present invention provides a new chemical process, a new cassette configuration, and new software for the automated production of multiple batches of an [18F]labelled compound on a single cassette. The invention allows one synthesizer in one hot cell to produce sequentially a plurality of batches of [18F]-labelled PET tracer in the same day. In particular, the present invention provides a novel arrangement useful for the trapping of [18F]fluoride and recovery of [18O]water.
    Type: Grant
    Filed: November 12, 2015
    Date of Patent: July 7, 2020
    Assignee: GE HEALTHCARE LIMITED
    Inventors: Xavier Franci, Steve Lignon, Audrey Marie Lange, Nicolas Verbrugge
  • PET tracer purification system
    Patent number: 10662125
    Abstract: The present invention provides a new chemical process, a new cassette configuration, and new software for the automated production of multiple batches of an [18F]-labelled compound on a single cassette. The invention allows one synthesizer in one hot cell to produce sequentially a plurality of batches of [18F]-labelled PET tracer in the same day. In particular, the present invention provides a novel arrangement useful for purifying two consecutive batches of a reaction mixture comprising an 18F-labelled compound.
    Type: Grant
    Filed: November 12, 2015
    Date of Patent: May 26, 2020
    Assignee: GE HEATLHCARE LIMITED
    Inventors: Xavier Franci, Steve Lignon, Audrey Marie Lange, Nicolas Verbrugge
  • SOLID PHASE CONDITIONING
    Publication number: 20200047158
    Abstract: The present invention relates to a method for conditioning reversed phase SPE cartridges that provides certain advantages compared with known such methods. The method of the invention finds particular use in the automated synthesis of radiolabeled compounds where SPE is used for example in the purification steps.
    Type: Application
    Filed: December 21, 2017
    Publication date: February 13, 2020
    Inventors: Nicolas VERBRUGGE, Xavier Y.A. FRANCI, Natthawadee THAWINWISAN
  • Piercing device
    Patent number: 10525435
    Abstract: The present invention provides a system for the production of a radiopharmaceutical including a radiosynthesis apparatus and a disposable cassette. The system of the invention includes a device that enables a position on the cassette to be freed for inclusion of an additional reagent vial. With the system of the invention a broader range of radiochemical syntheses can be envisaged using the cassette.
    Type: Grant
    Filed: March 10, 2016
    Date of Patent: January 7, 2020
    Assignee: GE HEALTHCARE LIMITED
    Inventors: Xavier Franci, Philippe Dumont, Steve Lignon, Audrey Marie Lange, Nicolas Verbrugge
  • Piercing Device
    Publication number: 20180008949
    Abstract: The present invention provides a system for the production of a radiopharmaceutical including a radiosynthesis apparatus and a disposable cassette. The system of the invention includes a device that enables a position on the cassette to be freed for inclusion of an additional reagent vial. With the system of the invention a broader range of radiochemical syntheses can be envisaged using the cassette.
    Type: Application
    Filed: March 10, 2016
    Publication date: January 11, 2018
    Applicant: GE Healthcare Limited
    Inventors: Xavier Franci, Philippe Dumont, Steve Lignon, Audrey Marie Lange, Nicolas Verbrugge
  • Fluoride Trapping Arrangement
    Publication number: 20170320901
    Abstract: The present invention provides a new chemical process, a new cassette configuration, and new software for the automated production of multiple batches of an [18F]labelled compound on a single cassette. The invention allows one synthesizer in one hot cell to produce sequentially a plurality of batches of [18F]-labelled PET tracer in the same day. In particular, the present invention provides a novel arrangement useful for the trapping of [18F]fluoride and recovery of [18O]water.
    Type: Application
    Filed: November 12, 2015
    Publication date: November 9, 2017
    Applicant: GE Healthcare Limited
    Inventors: Xavier Franci, Steve Lignon, Audrey Marie Lange, Nicolas Verbrugge
  • PET Tracer Purification System
    Publication number: 20170313632
    Abstract: The present invention provides a new chemical process, a new cassette configuration, and new software for the automated production of multiple batches of an [18F]-labelled compound on a single cassette. The invention allows one synthesizer in one hot cell to produce sequentially a plurality of batches of [18F]-labelled PET tracer in the same day. In particular, the present invention provides a novel arrangement useful for purifying two consecutive batches of a reaction mixture comprising an 18F-labelled compound.
    Type: Application
    Filed: November 12, 2015
    Publication date: November 2, 2017
    Applicant: GE Healthcare Limited
    Inventors: Xavier Franci, Steve Lignon, Audrey Marie Lange, Nicolas Verbrugge