Patents by Inventor Nicolay Ferrari

Nicolay Ferrari has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oligonucleotide Inhibitors with Chimeric Backbone and 2-Amino-2'-Deoxyadenosine
    Publication number: 20140163085
    Abstract: There is provided herein, an oligonucleotide directed against a target gene, wherein the oligonucleotide is capable of hybridizing to at least a portion of a nucleic acid sequence encoding the gene under stringent conditions, and wherein, at least one nucleotide of the oligonucleotide is 2-amino-2?-deoxyadenosine (DAP); and the internucleoside linkages of the oligonucleotide comprises at least three alternating segments, each segment consisting of either at least one phosphorothioate or at least one phosphodiester bond.
    Type: Application
    Filed: February 23, 2012
    Publication date: June 12, 2014
    Applicant: PHARMAXIS LTD
    Inventors: Rosanne Seguin, Nicolay Ferrari
  • OLIGONUCLEOTIDES FOR TREATING INFLAMMATION AND NEOPLASTIC CELL PROLIFERATION
    Publication number: 20140018408
    Abstract: There is provided oligonucleotides directed against the CCR3 receptor and the common beta sub-unit of IL-3, IL-5 and GMCSF receptors. The oligonucleotides are useful to inhibit general inflammation, including inflammation associated with asthma, COPD, allergy, Cystic fibrosis (CF), hypereosinophilia and neoplastic cell proliferation such as cancer.
    Type: Application
    Filed: May 22, 2013
    Publication date: January 16, 2014
    Inventors: Luc Paquet, Helene D'Anjou, Nicolay Ferrari
  • Oligonucleotides for treating inflammation and neoplastic cell proliferation
    Patent number: 8470999
    Abstract: There is provided oligonucleotides directed against the CCR3 receptor and the common beta sub-unit of IL-3, IL-5 and GM-CSF receptors. The oligonucleotides are useful to inhibit general inflammation, including inflammation associated with asthma, COPD, allergy, Cystic fibrosis (CF), hypereosinophilia and neoplastic cell proliferation such as cancer.
    Type: Grant
    Filed: March 31, 2009
    Date of Patent: June 25, 2013
    Inventors: Luc Paquet, Helene D'Anjou, Nicolay Ferrari
  • OLIGONUCLEOTIDES FOR TREATING INFLAMMATION AND NEOPLASTIC CELL PROLIFERATION
    Publication number: 20110144183
    Abstract: There is provided oligonucleotides directed against the CCR3 receptor and the common beta sub-unit of IL-3, IL-5 and GM-CSF receptors. The oligonucleotides are useful to inhibit general inflammation, including inflammation associated with asthma, COPD, allergy, Cystic fibrosis (CF), hypereosinophilia and neoplastic cell proliferation such as cancer.
    Type: Application
    Filed: March 31, 2009
    Publication date: June 16, 2011
    Inventors: Luc Paquet, Helene D'Anjou, Nicolay Ferrari
  • SMALL INTERFERING OLIGONUCLEOTIDES COMPRISING ARABINOSE MODIFIED NUCLEOTIDES
    Publication number: 20090298913
    Abstract: Small interfering ribonucleic acid duplexes that inhibit gene expression containing at least one arabinose modified nucleotide are provided. Preferably, the duplexes contain ribonucleotides at least one arabinose modified nucleotide is 2?-deoxy-2?-fluoroarabinonucleotide (FANA) nucleotide.
    Type: Application
    Filed: October 26, 2006
    Publication date: December 3, 2009
    Applicant: TOPIGEN PHARMACEUTICALS INC.
    Inventors: Masad Damha, Nicolay Ferrari
  • Combination of nitroderivatized steroid and bronchodilator for treating respiratory disease
    Publication number: 20090087425
    Abstract: There is provided a pharmaceutical composition for treating respiratory disease comprising an NO-donating steroid and at least one bronchodilator. Also provided is a method for treating respiratory diseases associated with inflammation comprising administering an NO-donating steroid with at least one bronchodilator. Method of use of the combination of an NO-donating compound, and a steroid with at least one bronchodilator for treating respiratory disease is also provided.
    Type: Application
    Filed: August 8, 2008
    Publication date: April 2, 2009
    Applicant: Topigen Pharmaceuticals Inc.
    Inventors: Paolo Renzi, Luc Paquet, Nicolay Ferrari