Patents by Inventor Nicolay V. Sinackevich

Nicolay V. Sinackevich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical tryptophan containing dipeptide compositions and methods of use thereof
    Publication number: 20030198617
    Abstract: The present invention provides compositions and methods for treatment of a variety of disease states. The methods generally comprise administering to a host a therapeutically effective amount of a dipeptide having the formula X-Tryptophan or a pharmaceutically acceptable salt thereof, wherein x is glutamine, glutamate, leucine, or isoleucine. The present invention is useful for treatment of infections hyperimmune states, immunodeficiencies, and the like.
    Type: Application
    Filed: June 6, 2002
    Publication date: October 23, 2003
    Inventors: Lawrence Green, Nicolay V. Sinackevich
  • Pharmaceutical lysine-containing polypeptide compositions and methods of use thereof
    Publication number: 20020052321
    Abstract: Pharmaceutical compositions and methods are provided for the therapy of immunodeficient, immunodepressed or hyperactive immune states and for the prevention and treatment of opportunistic infections in such states comprising administering to a subject a pharmaceutically acceptable composition comprising as an active ingredient peptides having the formula R′-L-Glx-L-Glx-L-Lys-R″ and/or their pharmaceutically acceptable salts; wherein Glx is Gln or Glu.
    Type: Application
    Filed: May 31, 2001
    Publication date: May 2, 2002
    Inventors: Lawrence R. Green, Nicolay V. Sinackevich, Vadim T. Ivanov, Inessa I. Mikhalyova, Boris V. Vaskovsky, Alexander N. Mikhaltsov, Vladimir K. Khavinson, Vyacheslav G. Morozov
  • Pharmaceutical lysine-containing polypeptide compositions and methods of use thereof
    Patent number: 6346514
    Abstract: Pharmaceutical compositions and methods are provided for the therapy of immunodeficient, immunodepressed or hyperactive immune states and for the prevention and treatment of opportunistic infections in such states comprising administering to a subject a pharmaceutically acceptable composition comprising as an active ingredient peptides having the formula R′-L-Glx-L-Glx-L-Lys-R″ and/or their pharmaceutically acceptable salts; wherein Glx is Gln or Glu.
    Type: Grant
    Filed: August 4, 1999
    Date of Patent: February 12, 2002
    Assignee: Cytran Incorporation
    Inventors: Lawrence R. Green, Nicolay V. Sinackevich, Vadim T. Ivanov, Inessa I. Mikhalyova, Boris V. Vaskovsky, Alexander N. Mikhaltsov, Vladimir K. Khavinson, Vyacheslav G. Morozov
  • Immunomodulating peptides and methods of use
    Patent number: 6066622
    Abstract: This invention provides methods of modulating the immune system by administering peptides of the formula R'-Glx-Glx-Lys-R" (SEQ ID NO:1) in which Glx is Glu or Gln. In particular, this invention provides the use of peptides Thr-Ala-Glu-Glu-Lys (SEQ ID NO:34) and Thr-Pro-Glu-Glu-Lys (SEQ ID NO:33).
    Type: Grant
    Filed: October 28, 1993
    Date of Patent: May 23, 2000
    Assignee: Cytran, Inc.
    Inventors: Lawrence R. Green, Nicolay V. Sinackevich, Vadim T. Ivanov, Inessa I. Mikhalyova, Boris V. Vaskovsky, Alexander N. Mikhaltsov, Vladimir K. Khavinson, Vyacheslav G. Morozov