Patents by Inventor Nicole A. Bakas

Nicole A. Bakas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHIBITORS OF ULK1/2 AND METHODS OF USING SAME
    Publication number: 20230135635
    Abstract: The present disclosure is directed to compounds, compositions, formulations and methods of use thereof in the treatment and prevention of ULK mediated diseases, including cancer.
    Type: Application
    Filed: February 12, 2021
    Publication date: May 4, 2023
    Inventors: Nicholas D.P. COSFORD, Nicole A. BAKAS, Mitchell VAMOS, Reuben J. SHAW, Allison S. LIMPERT, Sonja N. BRUN
  • MONO AND COMBINATION THERAPIES WITH ULK1/2 INHIBITORS
    Publication number: 20230130766
    Abstract: Provided herein are methods of treating diseases, including cancer, with ULK inhibitors, both as monotherapies and in combination with other therapeutic agents.
    Type: Application
    Filed: February 12, 2021
    Publication date: April 27, 2023
    Inventors: Nicholas D.P. COSFORD, Reuben J. SHAW, Nicole A. BAKAS, Allison S. LIMPERT, Sonja N. BRUN, Mitchell VAMOS
  • MACROCYCLIC ULK1/2 INHIBITORS
    Publication number: 20230099804
    Abstract: The present disclosure is directed to compounds, compositions, formulations and methods of use thereof in the treatment and prevention of ULK mediated diseases, including cancer.
    Type: Application
    Filed: February 12, 2021
    Publication date: March 30, 2023
    Inventors: Nicholas D.P. COSFORD, Nicole A. BAKAS, Reuben J. SHAW, Allison S. LIMPERT, Sonja N. BRUN
  • Immunoproteasome inhibitor analogs
    Patent number: 10584105
    Abstract: The disclosure provides for compounds having immunoproteasome inhibitory activity, and pharmaceutical compositions made thereof. The disclosure further provides for the use of the compounds and compositions in treating various diseases and disorders in a subject that are associated with immunoproteasome activity, including inflammatory disorders, autoimmune disorders, hematological disorders, and neurodegenerative disorders.
    Type: Grant
    Filed: March 10, 2017
    Date of Patent: March 10, 2020
    Assignees: The Regents of the University of California, Board of Trustees of the Michigan State University
    Inventors: Michael C. Pirrung, Nicole A. Bakas, Andre Bachmann
  • IMMUNOPROTEASOME INHIBITOR ANALOGS
    Publication number: 20190047969
    Abstract: The disclosure provides for compounds having immunoproteasome inhibitory activity, and pharmaceutical compositions made thereof. The disclosure further provides for the use of the compounds and compositions in treating various diseases and disorders in a subject that are associated with immunoproteasome activity, including inflammatory disorders, autoimmune disorders, hematological disorders, and neurodegenerative disorders.
    Type: Application
    Filed: March 10, 2017
    Publication date: February 14, 2019
    Inventors: Michael C. Pirrung, Nicole A. Bakas, Andre Bachmann