Patents by Inventor Nicole ALVAREZ

Nicole ALVAREZ has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Insulin immunoglobulin fusion proteins
    Patent number: 11421033
    Abstract: Disclosed herein are immunoglobulin fusion proteins comprising an insulin therapeutic peptide and an immunoglobulin region that targets the insulin therapeutic peptide to the liver of an individual in need thereof. Further disclosed herein are compositions comprising the immunoglobulin fusion proteins and methods for using the immunoglobulin fusion proteins for the treatment or prevention of a disease or condition in a subject, for example, diabetes and diabetes related conditions.
    Type: Grant
    Filed: October 24, 2019
    Date of Patent: August 23, 2022
    Assignee: THE SCRIPPS RESEARCH INSTITUTE
    Inventors: Feng Wang, Matthew S. Tremblay, Travis Young, Nicole Alvarez, Yan Liu, Juanjuan Du, Peter G. Schultz
  • INSULIN IMMUNOGLOBULIN FUSION PROTEINS
    Publication number: 20200115458
    Abstract: Disclosed herein are immunoglobulin fusion proteins comprising an insulin therapeutic peptide and an immunoglobulin region that targets the insulin therapeutic peptide to the liver of an individual in need thereof. Further disclosed herein are compositions comprising the immunoglobulin fusion proteins and methods for using the immunoglobulin fusion proteins for the treatment or prevention of a disease or condition in a subject, for example, diabetes and diabetes related conditions.
    Type: Application
    Filed: October 24, 2019
    Publication date: April 16, 2020
    Inventors: Feng WANG, Matthew S. TREMBLAY, Travis YOUNG, Nicole ALVAREZ, Yan LIU, Juanjuan DU, Peter G. SCHULTZ
  • Insulin immunoglobulin fusion proteins
    Patent number: 10501546
    Abstract: Disclosed herein are immunoglobulin fusion proteins comprising an insulin therapeutic peptide and an immunoglobulin region that targets the insulin therapeutic peptide to the liver of an individual in need thereof. Further disclosed herein are compositions comprising the immunoglobulin fusion proteins and methods for using the immunoglobulin fusion proteins for the treatment or prevention of a disease or condition in a subject, for example, diabetes and diabetes related conditions.
    Type: Grant
    Filed: September 2, 2016
    Date of Patent: December 10, 2019
    Assignee: THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH
    Inventors: Feng Wang, Matthew S. Tremblay, Travis Young, Nicole Alvarez, Yan Liu, Juanjuan Du, Peter G. Schultz
  • INSULIN IMMUNOGLOBULIN FUSION PROTEINS
    Publication number: 20190023794
    Abstract: Disclosed herein are immunoglobulin fusion proteins comprising an insulin therapeutic peptide and an immunoglobulin region that targets the insulin therapeutic peptide to the liver of an individual in need thereof. Further disclosed herein are compositions comprising the immunoglobulin fusion proteins and methods for using the immunoglobulin fusion proteins for the treatment or prevention of a disease or condition in a subject, for example, diabetes and diabetes related conditions.
    Type: Application
    Filed: September 2, 2016
    Publication date: January 24, 2019
    Inventors: Feng WANG, Matthew S. TREMBLAY, Travis YOUNG, Nicole ALVAREZ, Yan LIU, Juanjuan DU, Peter G. SCHULTZ
  • LPA RECEPTOR MODULATORS FOR BROWN FAT DIFFERENTIATION
    Publication number: 20170042915
    Abstract: Described herein is a method of increasing brown fat differentiation or increasing energy expenditure in a subject in need thereof, the method comprising administering to the subject an LPA receptor modulator, or a pharmaceutically acceptable salt, solvate, polymorph, prodrug, metabolite, deuteride, N-oxide, stereoisomer, or isomer thereof.
    Type: Application
    Filed: August 11, 2016
    Publication date: February 16, 2017
    Inventors: Matthew S. TREMBLAY, Nicole ALVAREZ, Weijun SHEN, Andrew TO