Patents by Inventor Nicole H. Levi

Nicole H. Levi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200384168
    Abstract: The present invention provides devices and methods that treat damaged spinal cord tissue, such as spinal tissue damaged by disease, infection, or trauma, which may lead to the presence of swelling, compression, and compromised blood flow secondary to interstitial edema.
    Type: Application
    Filed: April 8, 2020
    Publication date: December 10, 2020
    Inventors: Louis C. Argenta, David L. Carroll, Nicole H. Levi, Jie Liu, Michael J. Morykwas, Stephen Tatter, William D. Wagner
  • Patent number: 10632235
    Abstract: The present invention provides devices and methods that treat damaged spinal cord tissue, such as spinal tissue damaged by disease, infection, or trauma, which may lead to the presence of swelling, compression, and compromised blood flow secondary to interstitial edema.
    Type: Grant
    Filed: September 11, 2017
    Date of Patent: April 28, 2020
    Assignee: WAKE FOREST UNIVERSITY HEALTH SCIENCES
    Inventors: Louis C Argenta, David L Carroll, Nicole H Levi, Jie Liu, Michael J Morykwas, Stephen Tatter, William D Wagner
  • Publication number: 20190000433
    Abstract: A method and apparatus are provided for treating cardiac tissue to modulate ischemic heart tissue with topical sub-atmospheric pressure to minimize cell death and damage.
    Type: Application
    Filed: August 22, 2018
    Publication date: January 3, 2019
    Inventors: Louis C. Argenta, David L. Carroll, Nicole H. Levi, Michael J. Morykwas, James Eric Jordan, William D. Wagner, Jie Liu
  • Patent number: 10076318
    Abstract: A method and apparatus are provided for treating cardiac tissue to modulate ischemic heart tissue with topical sub-atmospheric pressure to minimize cell death and damage.
    Type: Grant
    Filed: February 19, 2015
    Date of Patent: September 18, 2018
    Assignee: WAKE FOREST UNIVERSITY HEALTH SCIENCES
    Inventors: Louis C Argenta, David L Carroll, Nicole H Levi, Michael J Morykwas, James Eric Jordan, William D Wagner, Jie Liu
  • Publication number: 20170368242
    Abstract: The present invention provides devices and methods that treat damaged spinal cord tissue, such as spinal tissue damaged by disease, infection, or trauma, which may lead to the presence of swelling, compression, and compromised blood flow secondary to interstitial edema.
    Type: Application
    Filed: September 11, 2017
    Publication date: December 28, 2017
    Inventors: Louis C. Argenta, David L. Carroll, Nicole H. Levi, Jie Liu, Michael J. Morykwas, Stephen Tatter, William D. Wagner
  • Patent number: 9671301
    Abstract: The present invention provides a method of sensing pressure in a region of interest by providing a plurality of metallic particles operatively associated with one another in the region of interest (for example, wherein the metallic particles sustain a plasmon upon excitation), and with the metallic particles configured or positioned in relationship to one another so that a physical property of the particles (for example, the energy of the plasmon) varies in response to pressure; measuring the physical property of the metallic particles that varies in response to pressure; and then determining the pressure in the region of interest from the detected physical property (e.g., resistance, energy of the plasmon). Compositions, articles and formulations for carrying out the method in industrial and biomedical applications are also described.
    Type: Grant
    Filed: September 28, 2007
    Date of Patent: June 6, 2017
    Assignee: Wake Forest University Health Sciences
    Inventors: David L. Carroll, Faith M. Coldren, Nicole H. Levi, Lawrence X. Webb, William D. Wagner, Thomas L. Smith, Brian Werner, J. Baxter Mcguirt, Manoj Namboothiry
  • Patent number: 9289193
    Abstract: A method and apparatus are provided for treating cardiac tissue to modulate ischemic heart tissue with topical sub-atmospheric pressure to minimize cell death and damage.
    Type: Grant
    Filed: July 16, 2009
    Date of Patent: March 22, 2016
    Assignee: Wake Forest University Health Sciences
    Inventors: Louis C. Argenta, David L. Carroll, James E. Jordan, Nicole H. Levi, Jie Liu, Michael J. Morykwas, William D. Wagner
  • Publication number: 20150367031
    Abstract: Biomedical implants, regenerative scaffolds, and compositions comprise a substrate with a coating, a scaffold, and/or a carrier composition which include anisotropic nanoparticles in or on the coating, scaffold or carrier, to inhibit fibrosis, scarring, and/or fibrotic contracture, or the formation of adhesions, in a tissue contacting or administered the same. In some embodiments the nanoparticles may be electrically conductive nanoparticles such as multi wall carbon nanotubes.
    Type: Application
    Filed: April 2, 2014
    Publication date: December 24, 2015
    Inventors: Louis Argenta, Nicole H. Levi, Michael Morykwas, Elizabeth Walles, Maria McGee, William D. Wagner, Elizabeth Graham
  • Patent number: 9131927
    Abstract: A method and apparatus are provided for treating cardiac tissue to modulate ischemic heart tissue with topical sub-atmospheric pressure to minimize cell death and damage.
    Type: Grant
    Filed: July 16, 2009
    Date of Patent: September 15, 2015
    Assignee: WAKE FOREST UNIVERSITY HEALTH SCIENCES
    Inventors: Louis C. Argenta, David L. Carroll, James E. Jordan, Nicole H. Levi, Jie Liu, Michael J. Morykwas, William D. Wagner
  • Publication number: 20150164492
    Abstract: A method and apparatus are provided for treating cardiac tissue to modulate ischemic heart tissue with topical sub-atmospheric pressure to minimize cell death and damage.
    Type: Application
    Filed: February 19, 2015
    Publication date: June 18, 2015
    Inventors: Louis C. Argenta, David L. Carroll, Nicole H. Levi-Polyachenko, Michael J. Morykwas, James Eric Jordan, William D. Wagner, Jie Liu
  • Publication number: 20140350497
    Abstract: The present invention relates generally to a device and method for treating tissues of the central nervous system and more particularly, but not exclusively, to a device and method for treating the brain tissue.
    Type: Application
    Filed: June 6, 2014
    Publication date: November 27, 2014
    Inventors: Louis C. Argenta, David L. Carroll, Nicole H. Levi, Michael J. Morykwas, Stephen Tatter, William D. Wagner, Jie Liu
  • Publication number: 20140350499
    Abstract: The present invention provides devices and methods that treat damaged spinal cord tissue, such as spinal tissue damaged by disease, infection, or trauma, which may lead to the presence of swelling, compression, and compromised blood flow secondary to interstitial edema.
    Type: Application
    Filed: August 13, 2014
    Publication date: November 27, 2014
    Inventors: Louis C. Argenta, David L. Carroll, Nicole H. Levi-Polyachenko, Jie Liu, Michael J. Morykwas, Stephen Tatter, William D. Wagner
  • Patent number: 8834520
    Abstract: The present invention provides devices and methods that treat damaged spinal cord tissue, such as spinal tissue damaged by disease, infection, or trauma, which may lead to the presence of swelling, compression, and compromised blood flow secondary to interstitial edema.
    Type: Grant
    Filed: October 9, 2008
    Date of Patent: September 16, 2014
    Assignee: Wake Forest University
    Inventors: Louis C. Argenta, David L. Carroll, Nicole H. Levi, Jie Liu, Michael J. Morykwas, Stephen Tatter, William D. Wagner
  • Patent number: 8764794
    Abstract: The present invention relates generally to a device and method for treating tissues of the central nervous system and more particularly, but not exclusively, to a device and method for treating the brain tissue.
    Type: Grant
    Filed: September 18, 2012
    Date of Patent: July 1, 2014
    Assignee: Wake Forest University Health Sciences
    Inventors: Louis C Argenta, David L Carroll, Nicole H Levi, Michael J Morykwas, Stephen B Tatter, William D Wagner, Jie Liu
  • Patent number: 8501233
    Abstract: The present invention relates to compositions and methods for treating cancer and, in particular, to composition and methods comprising nanostructures. In one embodiment, the present invention provides a composition comprising a mixture, the mixture comprising at least one nanoparticle and at least one chemotherapeutic.
    Type: Grant
    Filed: March 13, 2008
    Date of Patent: August 6, 2013
    Assignees: Wake Forest University, Wake Forest University Health Sciences
    Inventors: David Loren Carroll, John H. Stewart, IV, Nicole H. Levi
  • Publication number: 20100209479
    Abstract: The present invention relates to compositions and methods for treating cancer and, in particular, to composition and methods comprising nanostructures. In one embodiment, the present invention provides a composition comprising a mixture, the mixture comprising at least one nanoparticle and at least one chemotherapeutic.
    Type: Application
    Filed: March 13, 2008
    Publication date: August 19, 2010
    Inventors: David Loren Carroll, John H. Stewart, IV, Nicole H. Levi
  • Publication number: 20100185121
    Abstract: The present invention provides a method of sensing pressure in a region of interest by providing a plurality of metallic particles operatively associated with one another in the region of interest (for example, wherein the metallic particles sustain a plasmon upon excitation), and with the metallic particles configured or positioned in relationship to one another so that a physical property of the particles (for example, the energy of the plasmon) varies in response to pressure; measuring the physical property of the metallic particles that varies in response to pressure; and then determining the pressure in the region of interest from the detected physical property (e.g., resistance, energy of the plasmon). Compositions, articles and formulations for carrying out the method in industrial and biomedical applications are also described.
    Type: Application
    Filed: September 28, 2007
    Publication date: July 22, 2010
    Applicants: WAKE FOREST UNIVERSITY HEALTH SCIENCES, WAKE FOREST UNIVERSITY
    Inventors: David L. Carroll, Faith M. Coldren, Nicole H. Levi, Lawrence X. Webb, William D. Wagner, Thomas L. Smith, Brian Werner, J. Baxter Mcguirt, Manoj Namboothiry
  • Publication number: 20100121229
    Abstract: A method and apparatus are provided for treating cardiac tissue to modulate ischemic heart tissue with topical sub-atmospheric pressure to minimize cell death and damage.
    Type: Application
    Filed: July 16, 2009
    Publication date: May 13, 2010
    Inventors: Louis C. Argenta, David L. Carroll, James E. Jordan, Nicole H. Levi, Jie Liu, Michael J. Morykwas, William D. Wagner
  • Publication number: 20090187259
    Abstract: The present invention provides devices and methods that treat damaged spinal cord tissue, such as spinal tissue damaged by disease, infection, or trauma, which may lead to the presence of swelling, compression, and compromised blood flow secondary to interstitial edema.
    Type: Application
    Filed: October 9, 2008
    Publication date: July 23, 2009
    Inventors: Louis C. Argenta, David L. Carroll, Nicole H. Levi, Jie Liu, Michael J. Morykwas, Stephen Tatter