Patents by Inventor Nicole Hurst

Nicole Hurst has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120058979
    Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering to the patient a tetra-substituted pyrimidopyrimidine, either alone or in combination with one or more additional agents. The invention also features a composition containing a tetra-substituted pyrimidopyrimidine in combination with one or more additional agents.
    Type: Application
    Filed: November 9, 2011
    Publication date: March 8, 2012
    Applicant: Zalicus Inc.
    Inventors: Curtis Keith, Alexis Borisy, Grant R. Zimmermann, Edward Roydon Jost-Price, Palaniyandi Manivasakam, Nicole Hurst, Michael A. Foley, Michael S. Slavonic, Brendan Smith, Benjamin A. Auspitz
  • Patent number: 8080553
    Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering to the patient a tetra-substituted pyrimidopyrimidine, either alone or in combination with one or more additional agents. The invention also features a composition containing a tetra-substituted pyrimidopyrimidine in combination with one or more additional agents.
    Type: Grant
    Filed: September 7, 2006
    Date of Patent: December 20, 2011
    Assignee: Zalicus Inc.
    Inventors: Curtis Keith, Alexis Borisy, Grant R. Zimmermann, Edward Roydon Jost-Price, Palaniyandi Manivasakam, Nicole Hurst, Michael A. Foley, Michael S. Slavonic, Brendan Smith, Benjamin A. Auspitz
  • Publication number: 20100173881
    Abstract: The invention features methods and compositions for the treatment of immunonflammatory disorders.
    Type: Application
    Filed: January 22, 2010
    Publication date: July 8, 2010
    Inventors: Robyn Sackeyfio, Jason Fong, Nicole Hurst, Palaniyandi Manivasakam, Edward Roydon Jost-Price, Grant Zimmerrmann, Curtis Keith, Alexis Borisy
  • Publication number: 20090075951
    Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering a tricyclic compound and, optionally, a corticosteroid or other compound to the patient. The invention also features a pharmaceutical composition containing a tricyclic compound and a corticosteroid or other compound for the treatment or prevention of an immunoinflammatory disorder.
    Type: Application
    Filed: November 20, 2008
    Publication date: March 19, 2009
    Applicant: CombinatoRx, Inc.
    Inventors: Benjamin A. Auspitz, Alexis Borisy, Jason Fong, Nicole Hurst, Edward Roydon Jost-Price, Curtis T. Keith, Palaniyandi Manivasakam, Robyn Sackeyfio, Michael S. Slavonic, Brendan Smith, Grant R. Zimmermann
  • Publication number: 20080280863
    Abstract: The invention features methods and compositions for the treatment of immunoinflammatory disorders.
    Type: Application
    Filed: February 25, 2008
    Publication date: November 13, 2008
    Inventors: Robyn Sackeyfio, Jason Fong, Nicole Hurst, Palaniyandi Manivasakam, Edward Roydon Jost-Price, Grant Zimmermann, Curtis Keith, Alexis Borisy
  • Patent number: 7335371
    Abstract: The invention features methods and compositions for the treatment of immunonflammatory disorders.
    Type: Grant
    Filed: November 19, 2003
    Date of Patent: February 26, 2008
    Assignee: CombinatoRx, Incorporated
    Inventors: Robyn Sackeyfio, Jason Fong, Nicole Hurst, Palaniyandi Manivasakam, Edward Roydon Jost-Price, Grant Zimmermann, Curtis Keith, Alexis Borisy
  • Patent number: 7253155
    Abstract: The invention features a method for treating a patient having an immunoinflammatory disorder, by administering to the patient (i) a tetra-substituted pyrimidopyrimidine, and (ii) a corticosteroid simultaneously or within 14 days of each other in amounts sufficient to reduce or inhibit immunoinflammation.
    Type: Grant
    Filed: October 4, 2002
    Date of Patent: August 7, 2007
    Assignee: CombinatoRx, Inc.
    Inventors: Curtis Keith, Alexis Borisy, Grant Zimmerman, Edward Roydon Jost-Price, Palaniyandi Manivasakam, Nicole Hurst, Michael A. Foley
  • Publication number: 20070010502
    Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering to the patient a tetra-substituted pyrimidopyrimidine, either alone or in combination with one or more additional agents. The invention also features a composition containing a tetra-substituted pyrimidopyrimidine in combination with one or more additional agents.
    Type: Application
    Filed: September 7, 2006
    Publication date: January 11, 2007
    Applicant: CombinatoRx Inc.
    Inventors: Curtis Keith, Alexis Borisy, Grant Zimmermann, Edward Jost-Price, Palaniyandi Manivasakam, Nicole Hurst, Michael Foley, Michael Slavonic, Brendan Smith, Benjamin Auspitz
  • Publication number: 20060234991
    Abstract: The invention features pharmaceutical compositions that include dipyridamole and a corticosteroid.
    Type: Application
    Filed: February 15, 2006
    Publication date: October 19, 2006
    Inventors: Curtis Keith, Alexis Borisy, Grant Zimmermann, Edward Jost-Price, Palaniyandi Manivasakam, Nicole Hurst, Michael Foley
  • Publication number: 20060100181
    Abstract: The invention features methods and compositions for the treatment of inflammatory skin conditions.
    Type: Application
    Filed: May 2, 2003
    Publication date: May 11, 2006
    Inventors: Edward Jost-Price, Palaniyandi Manivasakam, Grant Zimmermann, Jason Fong, Nicole Hurst, Benjamin Auspitz, M Nichols, Curtis Keith
  • Patent number: 6955815
    Abstract: The invention features a pharmaceutical composition that includes amoxapine and a corticosteroid.
    Type: Grant
    Filed: September 29, 2003
    Date of Patent: October 18, 2005
    Assignee: CombinatoRx, Incorporated
    Inventors: Robyn Sackeyfio, Jason Fong, Nicole Hurst, Palaniyandi Manivasakam, Edward Roydon Jost-Price, Grant Zimmermann, Curtis Keith, Alexis Borisy
  • Publication number: 20050187200
    Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering a tricyclic compound and, optionally, a corticosteroid or other compound to the patient. The invention also features a pharmaceutical composition containing a tricyclic compound and a corticosteroid or other compound for the treatment or prevention of an immunoinflammatory disorder.
    Type: Application
    Filed: November 12, 2004
    Publication date: August 25, 2005
    Inventors: Benjamin Auspitz, Alexis Borisy, Jason Fong, Nicole Hurst, Edward Jost-Price, Curtis Keith, Palaniyandi Manivasakam, Robyn Sackeyfio, Michael Slavonic, Brendan Smith, Grant Zimmermann
  • Publication number: 20050159485
    Abstract: The invention features a method for treating a patient who has an immunoinflammatory disorder or a proliferative skin disease, or is at risk for developing an immunoinflammatory disorder or a proliferative skin disease, by administering to the patient a prostaglandin and a retinoid simultaneously or within 14 days of each other in amounts sufficient to reduce or inhibit immunoinflammatory or dermal/epidermal proliferation.
    Type: Application
    Filed: January 2, 2003
    Publication date: July 21, 2005
    Inventors: Edward Jost-Price, Palaniyandi Manivasakam, Grant Zimmermann, Nicole Hurst, Jason Fong, Curtis Keith, Alexis Borisy
  • Publication number: 20050119160
    Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering to the patient a tetra-substituted pyrimidopyrimidine, either alone or in combination with one or more additional agents. The invention also features a composition containing a tetra-substituted pyrimidopyrimidine in combination with one or more additional agents.
    Type: Application
    Filed: October 15, 2004
    Publication date: June 2, 2005
    Inventors: Curtis Keith, Alexis Borisy, Grant Zimmermann, Edward Jost-Price, Palaniyandi Manivasakam, Nicole Hurst, Michael Foley, Michael Slavonic, Brendan Smith, Benjamin Auspitz
  • Patent number: 6897206
    Abstract: The invention features a method for treating a patient having an inflammatory disorder, by administering to the patient (i) a tricyclic antidepressant (e.g., amoxapine); and (ii) a corticosteroid (e.g., prednisolone) simultaneously or within 14 days of each other in amounts sufficient to reduce or inhibit inflammation.
    Type: Grant
    Filed: July 9, 2002
    Date of Patent: May 24, 2005
    Assignee: CombinatoRx, Inc.
    Inventors: Robyn Sackeyfio, Jason Fong, Nicole Hurst, Palaniyandi Manivasakam, Edward Roydon Jost-Price, Grant Zimmermann, Curtis Keith, Alexis Borisy
  • Publication number: 20040253627
    Abstract: Embodiments of the invention are directed toward methods and devices for constructing assay arrays including a combination of constituent compositions from constituent arrays. The combined compositions are evaluated, in some embodiments of the invention, to identify combinations with a combination effect. Other embodiments of the invention are directed toward constructing constituent arrays in various configurations to facilitate the production of assay arrays. Such embodiments include: constructing constituent arrays and assay arrays with corresponding composition and assay control sets; constructing constituent arrays with a unique set of origin locations and corresponding sets of derivative locations; varying the concentrations utilized for a constituent composition; and composing assay arrays corresponding to a virtual sparse assay array. Other embodiments of the invention are directed towards systems and method of evaluating the activity of combined compositions in an assay array.
    Type: Application
    Filed: June 7, 2004
    Publication date: December 16, 2004
    Inventors: Grant Zimmermann, Raymond A. Molnar, Joseph Lehar, Jason Fong, Curtis T. Keith, George Serbedzija, Margaret S. Lee, Edward R. Jost-Price, Nicole Hurst, Alexis Borisy, Michael A. Foley, Brent Stockwell
  • Publication number: 20040253642
    Abstract: Embodiments of the invention are directed toward methods and devices for constructing assay arrays including a combination of constituent compositions from constituent arrays. The combined compositions are evaluated, in some embodiments of the invention, to identify combinations with a combination effect. Other embodiments of the invention are directed toward constructing constituent arrays in various configurations to facilitate the production of assay arrays. Such embodiments include: constructing constituent arrays and assay arrays with corresponding composition and assay control sets; constructing constituent arrays with a unique set of origin locations and corresponding sets of derivative locations; varying the concentrations utilized for a constituent composition; and composing assay arrays corresponding to a virtual sparse assay array. Other embodiments of the invention are directed towards systems and method of evaluating the activity of combined compositions in an assay array.
    Type: Application
    Filed: June 7, 2004
    Publication date: December 16, 2004
    Inventors: Grant Zimmermann, Raymond A. Molnar, Joseph Lehar, Jason Fong, Curtis T. Keith, George Serbedzija, Margaret S. Lee, Edward R. Jost-Price, Nicole Hurst, Alexis Borisy, Michael A. Foley, Brent Stockwell
  • Publication number: 20040116395
    Abstract: The invention features a pharmaceutical composition that includes amoxapine and a corticosteroid.
    Type: Application
    Filed: September 29, 2003
    Publication date: June 17, 2004
    Inventors: Robyn Sackeyfio, Jason Fong, Nicole Hurst, Palaniyandi Manivasakam, Edward Roydon Jost-Price, Grant Zimmermann, Curtis Keith, Alexis Borisy
  • Publication number: 20040110734
    Abstract: The invention features methods and compositions for the treatment of immunonflammatory disorders.
    Type: Application
    Filed: November 19, 2003
    Publication date: June 10, 2004
    Inventors: Robyn Sackeyflo, Jason Fong, Nicole Hurst, Palaniyandi Manivasakam, Edward Roydon Jost-Price, Grant Zimmermann, Curtis Keith, Alexis Borisy
  • Publication number: 20030119786
    Abstract: The invention features a method for treating a patient having an immunoinflammatory disorder, by administering to the patient (i) a tetra-substituted pyrimidopyrimidine, and (ii) a corticosteroid simultaneously or within 14 days of each other in amounts sufficient to reduce or inhibit immunoinflammation.
    Type: Application
    Filed: October 4, 2002
    Publication date: June 26, 2003
    Inventors: Curtis Keith, Alexis Borisy, Grant Zimmerman, Edward Roydon Jost-Price, Palaniyandi Manivasakam, Nicole Hurst, Michael A. Foley