Abstract: There is provided a microbial cell for producing at least one acyl amino acid, wherein the cell is genetically modified to comprise: a first genetic mutation that increases the expression relative to a wild type cell of at least one lipase (EC 3.1.1) (E1) capable of hydrolysing at least one glyceride to at least one fatty acid wherein the glyceride is a triglyceride; and a second and a third genetic mutation that increases the expression relative to a wild type cell of: (i) an amino acid-N-acyl-transferase (EC 2.3.1) (E2), and (ii) an acyl-CoA synthetase (EC 6.2.1.3) (E3) respectively that enables the cell to convert the fatty acid to at least one acyl amino acid and wherein the cell has a reduced fatty acid degradation capacity.

Abstract: The invention relates to a method comprising the steps a) providing isobutyric acid, b) bringing isobutyric acid into contact with the combination of isobutyrate kinase and phosphotransisobutyrylase and/or isobutyryl-coenzyme A synthetase/ligase and/or isobutyrate-coenzyme A transferase, c) bringing the product from step a) into contact with isobutyryl-coenzyme A dehydrogenase, d) bringing the product from step b) into contact with methacrylyl-coenzyme A hydratase, and e) hydrolyzing the product from step d) to form 3-hydroxyisobutyric acid, where at least one of the enzymes is used in the form of a cell which, compared to its wildtype, comprises a reduced activity of a 3-hydroxyisobutyric acid dehydrogenase or a variant thereof, a cell which has at least one enzyme from the group comprising isobutyryl-coenzyme A synthetase/ligase, isobutyrate-coenzyme A transferase, isobutyrate kinase, phosphotransisobutyrylase, isobutyryl-coenzyme A dehydrogenase, methacrylyl-coenzyme A hydratase and 3-hydroxyisobutyryl-coe

Abstract: Subject matter of the invention is a biotechnological process for the production of organic compounds with the aid of at least one alkL gene product.

Abstract: A sports glove includes a glove and a pouch. The glove is adapted to be worn on a first hand of a player, the glove having an inner portion and an outer portion. The pouch is attached to the outer portion of the glove and comprises an outer layer having a peripheral edge and being constructed of rugged but flexible material, and at least one inner layer having a peripheral edge and being constructed of an insulating material. The outer layer and the at least one inner layer are attached to the outer portion of the glove along at least a portion of their corresponding peripheral edges so as to thereby define an opening between the pouch and the glove such that the opening is oriented and sized to receive a second hand of the player while the glove is worn on the first hand of the player.