Patents by Inventor Nicole Lopanik

Nicole Lopanik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biosynthesis of bryostatins by polyketide synthases (PKS)
    Publication number: 20070026488
    Abstract: The present invention relates to the discovery, isolation and sequencing of novel polyketide synthase genes. These newly identified genes are involved in the biosynthesis of bryostatins. The genes are found to be expressed in all life stages of Bugula neritina, are associated with the bacterial symbiont Endobugula sertula and are believed to be part of a large polyketide gene cluster that is responsible for the production of bryostatins.
    Type: Application
    Filed: July 27, 2005
    Publication date: February 1, 2007
    Inventors: Nancy Targett, Nicole Lopanik
  • Bryostatin composition and bryostatin acquisition methodologies
    Patent number: 6900339
    Abstract: Methods for obtaining bryostatins from the marine bryozoans of the Bugula neritina species complex are provided wherein the methods involve the extraction and purification of bryostatins from the larvae of Bugula neritina organisms. Further, the present invention relates to a novel bryostatin composition that can be extracted from Bugula neritina.
    Type: Grant
    Filed: April 30, 2003
    Date of Patent: May 31, 2005
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Niels Lindquist, Nicole Lopanik
  • Bryostatin composition and bryostatin acquisition methodologies
    Publication number: 20030233000
    Abstract: Methods for obtaining bryostatins from the marine bryozoans of the Bugula neritina species complex are provided wherein the methods involve the extraction and purification of bryostatins from the larvae of Bugula neritina organisms. Further, the present invention relates to a novel bryostatin composition that may be extracted by Bugula neritina.
    Type: Application
    Filed: April 30, 2003
    Publication date: December 18, 2003
    Inventors: Niels Lindquist, Nicole Lopanik