Patents by Inventor Nicole Neuboeck

Nicole Neuboeck has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IL-6 detection based early diagnosis and prediction of systemic inflammatory response syndrome and sepsis in asymptomatic patients
    Patent number: 11635438
    Abstract: Methods, systems and kits for the early diagnosis or prediction of systemic inflammatory response syndrome (SIRS) including sepsis in asymptomatic patients, such as patients undergoing a surgical intervention, are provided. Some embodiments include a method and system for the detection or diagnosis of SIRS, or detection or diagnosis of a risk to suffer from or develop SIRS, in an asymptomatic patient comprising the steps of determining the level of IL-6 (or a variant thereof) in a sample from the patient; comparing the level of IL-6 (or a variant thereof) to a reference level; detecting or diagnosing SIRS or diagnosing a risk to suffer from or develop SIRS, wherein the sample is isolated at least 2 times at short intervals and the determining and comparing steps are both repeated for each sample. Also provided are methods, systems and kits for therapy monitoring and mortality prediction.
    Type: Grant
    Filed: June 29, 2016
    Date of Patent: April 25, 2023
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Susanne Grueb, Nicole Neuboeck, Freyja-Maria Smolle-Juettner, Annelie-Martina Weinberg
  • IL-6 DETECTION BASED EARLY DIAGNOSIS AND PREDICTION OF SYSTEMIC INFLAMMATORY RESPONSE SYNDROME AND SEPSIS IN ASYMPTOMATIC PATIENTS
    Publication number: 20160305957
    Abstract: Methods, systems and kits for the early diagnosis or prediction of systemic inflammatory response syndrome (SIRS) including sepsis in asymptomatic patients, such as patients undergoing a surgical intervention, are provided. Some embodiments include a method and system for the detection or diagnosis of SIRS, or detection or diagnosis of a risk to suffer from or develop SIRS, in an asymptomatic patient comprising the steps of determining the level of IL-6 (or a variant thereof) in a sample from the patient; comparing the level of IL-6 (or a variant thereof) to a reference level; detecting or diagnosing SIRS or diagnosing a risk to suffer from or develop SIRS, wherein the sample is isolated at least 2 times at short intervals and the determining and comparing steps are both repeated for each sample. Also provided are methods, systems and kits for therapy monitoring and mortality prediction.
    Type: Application
    Filed: June 29, 2016
    Publication date: October 20, 2016
    Inventors: Susanne Grueb, Nicole Neuboeck, Freyja-Maria Smolle-Juettner, Annelie-Martina Weinberg
  • IL-6 DETECTION BASED EARLY DIAGNOSIS AND PREDICTION OF SYSTEMATIC INFLAMMATORY RESPONSE SYNDROME AND SEPSIS IN ASYMPTOMATIC PATIENTS
    Publication number: 20130052671
    Abstract: Methods, systems and kits for the early diagnosis or prediction of systemic inflammatory response syndrome (SIRS) including sepsis in asymptomatic patients, such as patients undergoing a surgical intervention, are provided. Some embodiments include a method and system for the detection or diagnosis of SIRS, or detection or diagnosis of a risk to suffer from or develop SIRS, in an asymptomatic patient comprising the steps of determining the level of IL-6 (or a variant thereof) in a sample from the patient; comparing the level of IL-6 (or a variant thereof) to a reference level; detecting or diagnosing SIRS or diagnosing a risk to suffer from or develop SIRS, wherein the sample is isolated at least 2 times at short intervals and the determining and comparing steps are both repeated for each sample. Also provided are methods, systems and kits for therapy monitoring and mortality prediction.
    Type: Application
    Filed: August 31, 2012
    Publication date: February 28, 2013
    Applicants: MEDIZINISCHE UNIVERSITAT GRAZ, ROCHE DIAGNOSTICS OPERATIONS, INC.
    Inventors: Susanne Grueb, Freyja-Maria Smolle-Juettner, Nicole Neuboeck, Annelie-Martina Weinberg