Patents by Inventor Nicole S. White

Nicole S. White has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical formulations
    Patent number: 11273159
    Abstract: Provided herein are pharmaceutical formulations comprising a monoacylglycerol lipase (MAGL) inhibitor, or a pharmaceutically acceptable salt thereof, and at least one pharmaceutically acceptable excipient.
    Type: Grant
    Filed: November 15, 2017
    Date of Patent: March 15, 2022
    Assignee: H. LUNDBECK A/S
    Inventors: Cheryl A. Grice, Nicole S. White, Joel P. Zingerman, Hibreniguss Terefe, Isaac Ghebre-Sellassie
  • CRYSTALLINE FORMS OF A MAGL INHIBITOR
    Publication number: 20210147367
    Abstract: Described herein is new crystalline forms of the MAGL inhibitor 2-(2-((4-(((1,1,1,3,3,3-hexafluoropropan-2-yl)oxy)carbonyl)piperazin-1-yl)methyl)-5-(trifluoromethyl)phenoxy)-2-methylpropanoic acid, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: November 12, 2020
    Publication date: May 20, 2021
    Inventors: Cheryl A. GRICE, Daniel J. BUZARD, Michael B. SHAGHAFI, Nicole S. WHITE, Heidi LOPEZ DE DIEGO, Frans Dennis THERKELSEN, Ida Marie Brødsgaard KNUDSEN
  • PHARMACEUTICAL FORMLATIONS
    Publication number: 20200188393
    Abstract: Provided herein are pharmaceutical formulations comprising a monoacylglycerol lipase (MAGL) inhibitor, or a pharmaceutically acceptable salt thereof, and at least one pharmaceutically acceptable excipient.
    Type: Application
    Filed: November 15, 2017
    Publication date: June 18, 2020
    Inventors: Cheryl A. GRICE, Nicole S. WHITE, Joel P. ZINGERMAN, Hibreniguss TEREFE, Isaac GHEBRE-SELLASSIE
  • MAGL inhibitors
    Patent number: 9981930
    Abstract: Provided herein are piperazine carbamates and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of MAGL. Furthermore, the subject compounds and compositions are useful for the treatment of pain.
    Type: Grant
    Filed: November 15, 2017
    Date of Patent: May 29, 2018
    Assignee: ABIDE THERAPEUTICS, INC.
    Inventors: Cheryl A. Grice, Donald L. Hertzog, Daniel J. Buzard, Nicole S. White
  • MAGL INHIBITORS
    Publication number: 20180134675
    Abstract: Provided herein are piperazine carbamates and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of MAGL. Furthermore, the subject compounds and compositions are useful for the treatment of pain.
    Type: Application
    Filed: November 15, 2017
    Publication date: May 17, 2018
    Inventors: Cheryl A. GRICE, Donald L. HERTZOG, Daniel J. BUZARD, Nicole S. WHITE
  • Methods for preparing anti-viral nucleotide analogs
    Patent number: 9676804
    Abstract: Methods for isolating 9-{(R)-2-[((S)—{[(S)-1-(isopropoxycarbonyl)ethyl]amino}phenoxyphosphinyl)methoxy]propyl}adenine (compound 16): a method for preparing in high diastereomeric purity, intermediate compounds 13 and 15: and a method for preparing intermediate compound 12: 9-{(R)-2-[((S)—{[(S)-1-(isopropoxycarbonyl)ethyl]amino}phenoxyphosphinyl)methoxy]propyl}adenine has anti-viral properties.
    Type: Grant
    Filed: April 21, 2016
    Date of Patent: June 13, 2017
    Assignee: GILEAD SCIENCES, INC.
    Inventors: Denise A. Colby, Andrew Anthony Martins, Benjamin James Roberts, Robert William Scott, Nicole S. White
  • METHODS FOR PREPARING ANTI-VIRAL NUCLEOTIDE ANALOGS
    Publication number: 20160311840
    Abstract: Methods for isolating 9-{(R)-2-[((S)-{[(S)-1-(isopropoxycarbonyl)ethyl]amino}phenoxyphosphinyl)methoxy]propyl}adenine (compound 16): a method for preparing in high diastereomeric purity, intermediate compounds 13 and 15: and a method for preparing intermediate compound 12: 9-{(R)-2-[((S)-{[(S)-1-(isopropoxycarbonyl)ethyl]amino}phenoxyphosphinyl)methoxy]propyl}adenine has anti-viral properties.
    Type: Application
    Filed: April 21, 2016
    Publication date: October 27, 2016
    Inventors: Denise A. COLBY, Andrew Anthony MARTINS, Benjamin James ROBERTS, Robert William SCOTT, Nicole S. WHITE
  • Methods for preparing anti-viral nucleotide analogs
    Patent number: 9346841
    Abstract: Methods for isolating 9-{(R)-2-[((S)-{[(S)-1-(isopropoxycarbonyl)ethyl]amino}phenoxyphosphinyl)methoxy]propyl}adenine (compound 16): a method for preparing, in high diastereomeric purity, intermediate compounds 13 and 15: and a method for preparing intermediate compound 12: 9-{(R)-2-[((S)-{[(S)-1-(isopropoxycarbonyl)ethyl]amino}phenoxyphosphinyl)methoxy]propyl}adenine has anti-viral properties.
    Type: Grant
    Filed: April 8, 2015
    Date of Patent: May 24, 2016
    Assignee: Gilead Sciences, Inc.
    Inventors: Denise A. Colby, Andrew Anthony Martins, Benjamin James Roberts, Robert William Scott, Nicole S. White
  • METHODS FOR PREPARING ANTI-VIRAL NUCLEOTIDE ANALOGS
    Publication number: 20150291638
    Abstract: Methods for isolating 9-{(R)-2-[((S)-{[(S)-1-(isopropoxycarbonyl)ethyl]amino}phenoxyphosphinyl)methoxy]propyl}adenine (compound 16): a method for preparing, in high diastereomeric purity, intermediate compounds 13 and 15: and a method for preparing intermediate compound 12: 9-{(R)-2-[((S)-{[(S)-1-(isopropoxycarbonyl)ethyl]amino}phenoxyphosphinyl)methoxy]propyl}adenine has anti-viral properties.
    Type: Application
    Filed: April 8, 2015
    Publication date: October 15, 2015
    Inventors: Denise A. Colby, Andrew Anthony Martins, Benjamin James Roberts, Robert William Scott, Nicole S. White
  • Methods for preparing anti-viral nucleotide analogs
    Patent number: 9029534
    Abstract: Methods for isolating 9-{(R)-2-[((S)—{[(S)-1-(isopropoxycarbonyl)ethyl]amino}phenoxyphosphinyl)methoxy]propyl}adenine (compound 16): a method for preparing, in high diastereomeric purity, intermediate compounds 13 and 15: and a method for preparing intermediate compound 12: 9-{(R)-2-[((S)—{[(S)-1-(isopropoxycarbonyl)ethyl]amino}phenoxyphosphinyl)methoxy]propyl}adenine has anti-viral properties.
    Type: Grant
    Filed: January 14, 2014
    Date of Patent: May 12, 2015
    Assignee: Gilead Sciences, Inc.
    Inventors: Denise A. Colby, Andrew Anthony Martins, Benjamin James Roberts, Robert William Scott, Nicole S. White
  • METHODS FOR PREPARING ANTI-VIRAL NUCLEOTIDE ANALOGS
    Publication number: 20140128602
    Abstract: Methods for isolating 9-{(R)-2-[((S)—{[(S)-1-(isopropoxycarbonyl)ethyl]amino}phenoxyphosphinyl)methoxy]propyl}adenine (compound 16): a method for preparing, in high diastereomeric purity, intermediate compounds 13 and 15: and a method for preparing intermediate compound 12: 9-{(R)-2-[((S)—{[(S)-1-(isopropoxycarbonyl)ethyl]amino}phenoxyphosphinyl)methoxy]propyl}adenine has anti-viral properties.
    Type: Application
    Filed: January 14, 2014
    Publication date: May 8, 2014
    Applicant: GILEAD SCIENCES, INC.
    Inventors: Denise A. Colby, Andrew Anthony Martins, Benjamin James Roberts, Robert William Scott, Nicole S. White
  • Methods for preparing anti-viral nucleotide analogs
    Patent number: 8664386
    Abstract: Methods for isolating 9-{(R)-2-[((S)-{[(S)-1-(isopropoxycarbonyl)ethyl]amino}phenoxyphosphinyl)methoxy]propyl}adenine (compound 16): a method for preparing, in high diastereomeric purity, intermediate compounds 13 and 15: and a method for preparing intermediate compound 12: 9-{(R)-2-[((S)-{[(S)-1-(isopropoxycarbonyl)ethyl]amino}phenoxyphosphinyl)methoxy]propyl}adenine has anti-viral properties.
    Type: Grant
    Filed: October 3, 2012
    Date of Patent: March 4, 2014
    Assignee: Gilead Sciences, Inc.
    Inventors: Denise A. Colby, Andrew Anthony Martins, Benjamin James Roberts, Robert William Scott, Nicole S. White