Patents by Inventor Nicole Smits

Nicole Smits has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • VISTA AGONIST FOR TREATMENT/PREVENTION OF ISCHEMIC AND/OR REPERFUSION INJURY
    Publication number: 20230399405
    Abstract: This invention provides methods for treating and preventing injury caused by ischemia followed by reperfusion by the administration of VISTA agonist, optionally an agonist anti-VISTA antibody or VISTA fusion protein. This invention specifically relates to the treatment and prevention of ischemic reperfusion injury HRH and conditions associated therewith including myocardial infarction, cardiac surgery, stroke, solid organ transplant recipients and post-surgery acute kidney injury by the administration of an agonist anti-VISTA antibody.
    Type: Application
    Filed: November 4, 2021
    Publication date: December 14, 2023
    Inventors: Randolph J. NOELLE, Nicole SMITS
  • Methods for diagnosis or treatment of amyloidosis by targeting hyper-sulfated proteoglycans present in amyloid
    Publication number: 20100061934
    Abstract: Amyloid in an individual may be targeted by systemically administering to an individual a ligand that binds to a hyper-sulfated proteoglycan and permitting the ligand to bind to hyper-sulfated proteoglycans associated with amyloid within the body of the individual.
    Type: Application
    Filed: September 8, 2009
    Publication date: March 11, 2010
    Inventors: Jonathan Wall, Stephen Kennel, Toin van Kuppevelt, Nicole Smits