Patents by Inventor Nicole THIELENS

Nicole THIELENS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for preparing C1q recombinant protein
    Patent number: 10294284
    Abstract: The present invention relates to a method for recombinant production of a C1q protein or a variant of the C1q protein, in which the protein is recovered from an in vitro culture of cells expressing a C1qA subunit or a variant of the C1qA subunit, a C1qB subunit or a variant of the C1qB subunit, and a C1qC subunit or a variant of the C1qC subunit, in which at least one of the subunits or subunit variants also has at the N-terminus or C-terminus a sequence of amino acids of at least six residues, at least 40% of which are glutamic acid and/or aspartic acid residues.
    Type: Grant
    Filed: October 9, 2013
    Date of Patent: May 21, 2019
    Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, INSTITUT NATIONAL DE LA SANTE DE LA RECHERCHE MEDICALE (INSERM)
    Inventors: Nicole Thielens, Isabelle Bally
  • METHOD FOR PREPARING C1Q RECOMBINANT PROTEIN
    Publication number: 20150329606
    Abstract: The present invention relates to a method for recombinant production of a C1q protein or a variant of the C1q protein, in which the protein is recovered from an in vitro culture of cells expressing a C1qA subunit or a variant of the C1qA subunit, a C1qB subunit or a variant of the C1qB subunit, and a C1qC subunit or a variant of the C1qC subunit, in which at least one of the subunits or subunit variants also has at the N-terminus or C-terminus a sequence of amino acids of at least six residues, at least 40% of which are glutamic acid and/or aspartic acid residues.
    Type: Application
    Filed: October 9, 2013
    Publication date: November 19, 2015
    Inventors: Nicole THIELENS, Isabelle BALLY