Patents by Inventor Nicole Wyttenbach
Nicole Wyttenbach has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11814354Abstract: The disclosure is in part directed to crystalline forms of 5-(3,4-dichlorophenyl)-N-((1R,2R)-2-hydroxycyclohexyl)-6-(2,2,2-trifluoroethoxy)nicotinamide and pharmaceutical compositions thereof.Type: GrantFiled: September 7, 2022Date of Patent: November 14, 2023Assignee: River 3 Renal Corp.Inventors: He Hongyan, Jiang Siyi, Urs Schwitter, Pascal Jean Claude Dott, Ralph Diodone, Nicole Wyttenbach, Olaf Grassmann
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Publication number: 20230242485Abstract: The disclosure is in part directed to crystalline forms of 5-(3,4-dichlorophenyl)-N-((1R,2R)-2-hydroxycyclohexyl)-6-(2,2,2-trifluoroethoxy)nicotinamide and pharmaceutical compositions thereof.Type: ApplicationFiled: September 7, 2022Publication date: August 3, 2023Applicants: River 3 Renal Corp., Hoffmann-La Roche Inc.Inventors: He Hongyan, Jiang Siyi, Urs Schwitter, Pascal Jean Claude Dott, Ralph Diodone, Nicole Wyttenbach, Olaf Grassmann
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Patent number: 11491109Abstract: The present invention provides novel, solid or liquid pharmaceutical preparations comprising a basic or neutral, low molecular weight active pharmaceutical ingredient and the polymer Eudragit® EPO, optionally together with additional pharmaceutically acceptable excipients. The present preparations are for oral or topical administration.Type: GrantFiled: February 14, 2020Date of Patent: November 8, 2022Assignee: Hoffmann-La Roche Inc.Inventors: Jochem Alsenz, Martin Kuentz, Alfred Ross, Wiebke Svea Saal, Nicole Wyttenbach
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Publication number: 20200206133Abstract: The present invention provides novel, solid or liquid pharmaceutical preparations comprising a basic or neutral, low molecular weight active pharmaceutical ingredient and the polymer Eudragit® EPO, optionally together with additional pharmaceutically acceptable excipients. The present preparations are for oral or topical administration.Type: ApplicationFiled: February 14, 2020Publication date: July 2, 2020Applicant: Hoffmann-La Roche Inc.Inventors: Jochem ALSENZ, Martin KUENTZ, Alfred ROSS, Wiebke Svea SAAL, Nicole WYTTENBACH
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Publication number: 20190241557Abstract: Provided are solid dispersions, solid molecular complexes, salts and crystalline polymorphs involving propane-1-sulfonic acid {3-[5-(4-chloro-phenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluoro-phenyl}-amide.Type: ApplicationFiled: September 6, 2018Publication date: August 8, 2019Inventors: Dipen Desai, Ralph Diodone, Zenaida Go, Prabha N. Ibrahim, Raman Iyer, Hans-Juergen Mair, Harpreet K. Sandhu, Navnit H. Shah, Gary Visor, Nicole Wyttenbach, Stephan Lauper, Johannes Pudewell, Frank Wierschem
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Publication number: 20180111930Abstract: Provided are solid dispersions, solid molecular complexes, salts and crystalline polymorphs involving propane-1-sulfonic acid {3-[5-(4-chloro-phenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluoro-phenyl}-amide.Type: ApplicationFiled: May 26, 2017Publication date: April 26, 2018Inventors: Dipen Desai, Ralph Diodone, Zenaida Go, Prabha N. Ibrahim, Raman Iyer, Hans-Juergen Mair, Harpreet K. Sandhu, Navnit H. Shah, Gary Visor, Nicole Wyttenbach, Stephen Lauper, Johannes Pudewell, Frank Wierschem
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Publication number: 20170281602Abstract: The present invention relates to solid forms of (S)-2-methoxy-3-{442-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxyl-benzo[b]thiophen-7-yl}-propionic acid, and of salts of (S)-2-methoxy-3-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-benzo[b]thiophen-7-yl}-propionic acid.Type: ApplicationFiled: June 14, 2017Publication date: October 5, 2017Applicant: Hoffmann-La Roche Inc.Inventors: Lukas Dreier, Andre Egli, Karsten Faehnrich, Olaf Grassmann, Peter Mohr, Urs Schwitter, Helmut Stahr, Nicole Wyttenbach
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Patent number: 9663517Abstract: Provided are solid dispersions, solid molecular complexes, salts and crystalline polymorphs involving propane-1-sulfonic acid {3-[5-(4-chloro-phenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluoro-phenyl}-amide.Type: GrantFiled: August 19, 2016Date of Patent: May 30, 2017Assignees: Plexxikon Inc., Hoffman-La Roche Inc.Inventors: Dipen Desai, Ralph Diodone, Zenaida Go, Prabha N. Ibrahim, Raman Iyer, Hans-Juergen Mair, Harpreet K. Sandhu, Navnit H. Shah, Gary Visor, Nicole Wyttenbach, Stephan Lauper, Johannes Pudewell, Frank Wierschem
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Publication number: 20160355513Abstract: Provided are solid dispersions, solid molecular complexes, salts and crystalline polymorphs involving propane-1-sulfonic acid {3-[5-(4-chloro-phenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluoro-phenyl}-amide.Type: ApplicationFiled: August 19, 2016Publication date: December 8, 2016Inventors: Dipen Desai, Ralph Diodone, Zenaida Go, Prabha N. Ibrahim, Raman Iyer, Hans-Juergen Mair, Harpreet K. Sandhu, Navnit H. Shah, Gary Visor, Nicole Wyttenbach, Stephan Lauper, Johannes Pudewell, Frank Wierschem
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Patent number: 9447089Abstract: Provided are solid dispersions, solid molecular complexes, salts and crystalline polymorphs involving propane-1-sulfonic acid {3-[5-(4-chloro-phenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluoro-phenyl}-amide.Type: GrantFiled: March 31, 2010Date of Patent: September 20, 2016Assignees: Plexxikon Inc., Hoffman-La Roche Inc.Inventors: Dipen Desai, Ralph Diodone, Zenaida Go, Prabha N. Ibrahim, Raman Iyer, Hans-Juergen Mair, Harpreet K. Sandhu, Navnit H. Shah, Gary Visor, Nicole Wyttenbach, Stephan Lauper, Johannes Pudewell, Frank Wierschem
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Publication number: 20150182505Abstract: The present invention relates to solid forms of (S)-2-methoxy-3-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-benzo[b]thiophen-7-yl}-propionic acid, and of salts of (S)-2-methoxy-3-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-benzo[b]thiophen-7-yl}-propionic acid.Type: ApplicationFiled: March 11, 2015Publication date: July 2, 2015Applicant: HOFFMANN-LA ROCHE INC.Inventors: Lukas Dreier, Andre Egli, Karsten Faehnrich, Olaf Grassman, Peter Mohr, Urs Schwitter, Helmut Stahr, Nicole Wyttenbach
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Patent number: 8975397Abstract: The instant invention relates to novel solid forms of the compound of formula (I) as well as solvates, inclusion complexes with other suitable compounds, processes for their manufacture, pharmaceutical compositions containing these solid forms, and their use as pharmaceuticals.Type: GrantFiled: June 4, 2014Date of Patent: March 10, 2015Assignee: Hoffmann-La Roche Inc.Inventors: Pascal Dott, Olaf Grassmann, Michael Kammerer, Joachim Manns, Urs Schwitter, Andrew Thomas, Nicole Wyttenbach
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Publication number: 20140329806Abstract: The instant invention relates to novel solid forms of the compound of formula (I) as well as solvates, inclusion complexes with other suitable compounds, processes for their manufacture, pharmaceutical compositions containing these solid forms, and their use as pharmaceuticals.Type: ApplicationFiled: June 4, 2014Publication date: November 6, 2014Applicant: Hoffmann-La Roche Inc.Inventors: Pascal Dott, Olaf Grassmann, Michael Kammerer, Joachim Manns, Urs Schwitter, Andrew Thomas, Nicole Wyttenbach
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Patent number: 8785435Abstract: The instant invention relates to novel solid forms of the compound of formula (I) as well as solvates, inclusion complexes with other suitable compounds, processes for their manufacture, pharmaceutical compositions containing these solid forms, and their use as pharmaceuticals.Type: GrantFiled: October 12, 2012Date of Patent: July 22, 2014Assignee: Hoffmann-La Roche Inc.Inventors: Pascal Dott, Olaf Grassmann, Michael Kammerer, Joachim Manns, Urs Schwitter, Andrew Thomas, Nicole Wyttenbach
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Publication number: 20100310659Abstract: Provided are solid dispersions, solid molecular complexes, salts and crystalline polymorphs involving propane-1-sulfonic acid {3-[5-(4-chloro-phenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluoro-phenyl}-amide.Type: ApplicationFiled: March 31, 2010Publication date: December 9, 2010Inventors: Dipen Desai, Ralph Diodone, Zenaida Go, Prabha N. Ibrahim, Raman Iyer, Hans-Juergen Mair, Harpreet K. Sandhu, Navnit H. Shah, Gary Visor, Nicole Wyttenbach, Stephan Lauper, Johannes Pudewell, Frank Wierschem