Patents by Inventor Nicolino Ruperto

Nicolino Ruperto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160280776
    Abstract: The invention provides methods, uses and compositions for the treatment of juvenile rheumatoid arthritis (JRA). The invention describes methods and uses for treating JRA, wherein a TNF? inhibitor, such as a human TNF? antibody, or antigen-binding portion thereof, is used to prevent flare-ups associated with JRA. Also described are methods for determining the efficacy of a TNF? inhibitor for treatment of JRA in a subject.
    Type: Application
    Filed: November 9, 2015
    Publication date: September 29, 2016
    Inventors: John R. Medich, Nicolino Ruperto, Alberto Martini, Daniel J. Lovell, Edward H. Giannini
  • Publication number: 20160004828
    Abstract: The invention relates to a method for determining the activity of an autoinflammatory disease in a patient, where a patient reports the status of at least 5 dichotomous items corresponding to a physiological observation and the values of each status is combined in a mathematical function to obtain an end value.
    Type: Application
    Filed: February 28, 2014
    Publication date: January 7, 2016
    Applicants: Assistance Publique - Hôpitaux de Paris, Universite Paris-Sud, Istituto Giannina Gaslini
    Inventors: Isabelle Koné-Paut, Maryam Piram, Marco Gattorno, Nicolino Ruperto
  • Publication number: 20080118496
    Abstract: The invention provides methods, uses and compositions for the treatment of juvenile rheumatoid arthritis (JRA). The invention describes methods and uses for treating JRA, wherein a TNF? inhibitor, such as a human TNF? antibody, or antigen-binding portion thereof, is used to prevent flare-ups associated with JRA. Also described are methods for determining the efficacy of a TNF? inhibitor for treatment of JRA in a subject.
    Type: Application
    Filed: June 11, 2007
    Publication date: May 22, 2008
    Inventors: John R. Medich, Nicolino Ruperto, Alberto Martini, Daniel J. Lovell, Edward Giannini