Abstract: A cable-pull actuation system for a parking brake may have a body which houses an electric motor device. A rod, adapted to operate along an actuation direction, at a first end thereof, an actuation member of a drum brake and/or of a parking brake. A transmission device may operatively connect the electric motor device to a second end of the rod which is translationally integral with a screw. The screw may be engaged with a nut screw rotationally actuated by the transmission device. A pre-loading device may act in contrast on the screw. The pre-loading device may be compressively pre-loaded to exert a pre-load traction on the rod to offset variations of load on the rod. The pre-loading device may be configured to exert a thrust action on the rod following the annulment of axial clearances for an incremental compression of the pre-loading device with respect to the pre-load value.

Abstract: The present invention relates to an isolated polynucleotide comprising from 5? to 3?: a first homology region, a splice acceptor sequence, a nucleotide sequence encoding a RAG1 polypeptide, and a second homology region for use in treating a RAG-deficient immunodeficiency.

Abstract: Embodiments described herein relate to systems and methods of retinal injection. In some aspects, a method includes inserting a distal end portion of a hollow conduit of a medical injector into an eye of a patient until the distal end portion reaches a reference location, the medical injector having a housing from which the hollow conduit distally extends and confirming disposal of the distal end portion of the hollow conduit in the reference location. After the confirming, the method further includes extending the distal end portion of the hollow conduit distally relative to the housing and from the reference location such that the distal end portion enters an injection region of the eye. With the distal end portion of the hollow conduit disposed in the injection region of the eye, medicament is conveyed into the injection region via the hollow conduit.

Abstract: A lithium ion capacitor includes binder free positive and negative electrode active layers. The capacitor exhibits high energy density, power density and cycle life and provides a good compromise in performance between an electric double layer capacitor and a lithium ion battery.

Abstract: Disclosed herein is an energy storage cell comprising a first electrode; a second electrode; a permeable separator disposed between the first electrode and the second electrode; and an electrolyte wetting the first and second electrodes; wherein the first electrode comprises a network of dements defining void spaces within the network; and active material comprising lithium metal oxide disposed in the void spaces within the network and enmeshed in the network; wherein the electrode active layer contains less than 0.1% percent by weight of polymeric binders disposed in the void spaces; and wherein the active layer is greater than 99% by weight active material.

Abstract: An electrode for an energy storage device is disclosed. The electrode includes an active layer. The active layer includes a network of high aspect ratio carbon elements defining void spaces within the network, a plurality of electrode active material particles disposed in the void spaces within the network, wherein the active material particles comprise silicon, and a polymeric additive, the polymeric additive being at least one of a polyolefin, a Poly(acrylic acid), and a styrene-butadiene rubber (SBR).

Abstract: An industrial paper sack of the valve type, includes a tubular side wall extending along a longitudinal axis, a first bottom arranged on one side of the tubular side wall along a direction parallel to the longitudinal axis and a second bottom arranged on an opposite side with respect to the first bottom along the direction parallel to the longitudinal axis. The first bottom includes a filling opening of the sack, configured to be sealed after the filling of the sack. The second bottom is folded at a first folding line to form a first folded bottom portion and includes, at a free end of the first folded bottom portion, an emptying opening of the sack. The first folded bottom portion is coupled to the tubular side wall by a removable coupling device.

Abstract: A device for intermediately storing and conveying containers in at least one conveying direction includes a multi-row intermediate storage device. The device also includes container outlet lanes arranged, in a conveying direction, downstream of the multi-row intermediate storage device. The device also includes at least one movable container outlet link each configured to receive containers from at least one row of the multi-row intermediate storage device, and to discharge and distribute the containers to a plurality of the container outlet lanes.

Abstract: A method for fabricating an electrode for an energy storage device is provided. The method includes heating a mixture of solvent and materials for use as energy storage media; adding active material to the mixture; adding dispersant to the mixture to provide a slurry; coating a current collector with the slurry; and calendaring the coating of slurry on the current collector to provide the electrode.

Abstract: A steerable endoscope system includes a continuum manipulator, a plurality of syringes, and a steerable tip. The continuum manipulator includes a plurality of spaced discs and a plurality of backbones each extending through all discs. A bending movement of the continuum manipulator changes a varying linear displacement of each backbone. Each backbone is further coupled to a different one of the syringes such that the linear displacement of each backbone pushes or pulls a piston of the corresponding syringe by a varying amount. The steerable tip includes a plurality of bellows each pneumatically coupled to a different syringe such that movement of the piston of a syringe causes the corresponding bellow to inflate or deflate. Because the distal end of each bellow is fixedly coupled to the same end effector, variations in the amount of inflation or deflation on each bellow causes a bending of the steerable tip.

Abstract: A microfluidic device for the isolation of particles of at least one specific type of a sample is described. The microfluidic device comprises: a first inlet adapted to receive a sample comprising the particles of the specific type, at least part of a separation group comprising a separation unit, which comprises a main chamber and a recovery chamber and being adapted to receive the sample and to transfer at least part of the particles of the specific type from the main chamber to the recovery chamber in a selective manner with respect to further particles of the sample, a first outlet which is designed to allow the particles of the specific type to be collected outside of the device and a second outlet adapted to allow at least a portion of the sample to flow out of the main chamber and out of the microfluidic device.

Abstract: For manufacturing an optical microelectromechanical device, a first wafer of semiconductor material having a first surface and a second surface is machined to form a suspended mirror structure, a fixed structure surrounding the suspended mirror structure, elastic supporting elements which extend between the fixed structure and the suspended mirror structure, and an actuation structure coupled to the suspended mirror structure. A second wafer is machined separately to form a chamber delimited by a bottom wall having a through opening. The second wafer is bonded to the first surface of the first wafer in such a way that the chamber overlies the actuation structure and the through opening is aligned to the suspended mirror structure. Furthermore, a third wafer is bonded to the second surface of the first wafer to form a composite wafer device. The composite wafer device is then diced to form an optical microelectromechanical device.

Abstract: An extruder for additive manufacturing extends about, and along, a longitudinal axis and has an extrusion nozzle having a polygonal cross-section and a mounting member provided with: a ring configured to be mounted to a bearing coaxial to the extruder and allowing the rotation of the mounting member about the longitudinal axis; a hollow body arranged within the ring and configured to house, in part, an extrusion screw; and a plurality of spokes for connecting the hollow body to the ring so as to define compartments between the spokes-adjacent the hollow body and the ring.

Abstract: A microelectromechanical mirror device has, in a die of semiconductor material: a fixed structure defining a cavity; a tiltable structure carrying a reflecting region, elastically suspended above the cavity and having a main extension in a horizontal plane; at least one first pair of driving arms, carrying respective piezoelectric structures which can be biased to generate a driving force that causes rotation of the tiltable structure about a rotation axis parallel to a first horizontal axis of the horizontal plane; elastic suspension elements, which elastically couple the tiltable structure to the fixed structure at the rotation axis and are rigid to movements out of the horizontal plane and compliant to torsion about the rotation axis. In particular, the driving arms of the first pair are magnetically coupled to the tiltable structure to cause its rotation about the rotation axis by magnetic interaction, following biasing of the respective piezoelectric structures.

Abstract: A voltage-controlled oscillator in a phase-locked loop circuit is calibrated via a dichotomous search in a set of candidate frequency bands via a sequence of subsequent halving steps that produce reduced subsets of the set of candidate frequency bands. The reduced subsets have respective upper bound values and lower bound values, as well as central values. The central value of the subset resulting from the halving step of index i in the sequence is a function of the average of the upper bound value and the lower bound value of the subset resulting from the halving step of index i?1 in the sequence.

Abstract: Determining whether, upon cessation of a second automated assistant session that interrupted and supplanted a prior first automated assistant session: (1) to automatically resume the prior first automated assistant session, or (2) to transition to an alternative automated assistant state in which the prior first session is not automatically resumed. Implementations further relate to selectively causing, based on the determining and upon cessation of the second automated assistant session, either the automatic resumption of the prior first automated assistant session that was interrupted, or the transition to the state in which the first session is not automatically resumed.

Abstract: Method for determining a first and a second calibrated value of atmospheric pressure, performed by an electronic apparatus comprising a fixed device and a first and a second movable device comprising respectively a first and a second movable barometer.

Abstract: An assembly includes an insertion device and a suture delivery device. The insertion device includes a longitudinal guide member extending from a proximal end to a distal tip. The tip includes an abutting structure movable between insertion and open positions. The structure is sized and shaped to contact tissue surrounding the tissue opening into which the insertion device has been inserted to maintain a desired position of the insertion device within the opening. The delivery device includes a body and a tube. The tube extends along a curved path configured so that, as the tube is rotated about the member, the tube penetrates tissue surrounding the opening into which the member has been inserted. A distal extension of the tube is configured so that, when the tube has been advanced distally to a distal-most position on the member, a distal end of the tube is proximal of the structure.

Abstract: A waste water processing system includes an upflow contacting column having a flue gas input for receiving flue gas having a temperature of at least 500 degrees F., a waste water input, and a flue gas output. The waste water input is coupled to a fluid injector, e.g., atomizing nozzles, positioned in the throat of a Venturi portion of the upflow contacting column or in a sidewall of the throat of the Venturi portion of the upflow contacting column. The flue gas in the upflow contacting column has a high velocity, e.g., a gas velocity exceeding 65 fps in the throat of the Venturi portion of the upflow contacting column at a position where the fluid injector is located. Drying additives such as recycled ash, lime, and/or cement may be, and sometimes are, input into the upflow contacting column downstream of the waste water input.

Abstract: An energy storage apparatus suitable for mounting on a printed circuit board using a solder reflow process is disclosed. In some embodiments, the apparatus includes: a sealed housing body (e.g., a lower body with a lid attached thereto) including a positive internal contact and a negative internal contact (e.g., metallic contact pads) disposed within the body and each respectively in electrical communication with a positive external contact and a negative external contact. Each of the external contacts provide electrical communication to the exterior of the body, and may be disposed on an external surface of the body. An electric double layer capacitor (EDLC) (also referred to herein as an “ultracapacitor” or “supercapacitor”) energy storage cell is disposed within a cavity in the body including a stack of alternating electrode layers and electrically insulating separator layers. An electrolyte is disposed within the cavity and wets the electrode layers.