Patents by Inventor Nicos Antony Nicola

Nicos Antony Nicola has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Receptor-binding determinant from leukaemia inhibitory factor
    Patent number: 6184370
    Abstract: The present invention relates generally to molecules carrying one or more binding determinants for &agr;-chain of human Leukaemia Inhibitory Factor binding receptor and to genetic sequences encoding same. More particularly, the present invention contemplates a molecule which is non-naturally occurring and which comprises a carrier portion and an active portion and wherein the active portion comprises amino acid residues or chemical equivalents thereof which constitute a binding determinant for the &agr; chain of the human leukaemia inhibitory factor (hLIF) binding receptor.
    Type: Grant
    Filed: September 27, 1995
    Date of Patent: February 6, 2001
    Assignee: Amrad Corporation Limited
    Inventors: Meredith Jane Layton, Catherine Mary Owczarek, Nicos Antony Nicola, Nicholas Martin Gough, Donald Metcalf
  • Monoclonal antibody to human granulocyte macrophage colony stimulating factor
    Patent number: 5747032
    Abstract: The invention relates to monoclonal antibodies specific for the receptor for human granulocyte-macrophage colony stimulating factor (hGM-CSF). The antibodies inhibit the biological activity of hGM-CSF. Methods and compositions for treatment of GM-CSF dependent condition, and methods for screening of selective antagonists to GM-CSF, are also disclosed and claimed.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: May 5, 1998
    Assignee: Amrad Corporation Limited
    Inventors: Donald Metcalf, Nicos Antony Nicola, Andrew Wallace Boyd, Judith Eleanor Layton, Kaye Wycherley