Abstract: The present disclosure provides therapeutic combinations, which provide a synergistic effect in treating a cancer. The present disclosure provides methods of treatment including administration of the combinations, and uses of the combinations, e.g., for treatment of cancer.

Abstract: System, method, and program products offer flexibility to the rather rigid way of trading in an electronic trading system. Orders for a tradeable object may typically get matched according to set terms and/or conditions at an electronic exchange. A trader may log onto the electronic exchange to trade the tradeable object, and may choose to display and trade the tradeable object according to a different set of terms and/or conditions. As such, the market data sent to the trader from the exchange is converted to a format according to the trader's selection, so that it may be presented to the trader in this format. Transaction messages sent to the exchange from the trader are converted to the format readable by the matching process, so that it can process the messages. Other features and advantages are described herein.

Abstract: System, method, and program products offer flexibility to the rather rigid way of trading in an electronic trading system. Orders for a tradeable object may typically get matched according to set terms and/or conditions at an electronic exchange. A trader may log onto the electronic exchange to trade the tradeable object, and may choose to display and trade the tradeable object according to a different set of terms and/or conditions. As such, the market data sent to the trader from the exchange is converted to a format according to the trader's selection, so that it may be presented to the trader in this format. Transaction messages sent to the exchange from the trader are converted to the format readable by the matching process, so that it can process the messages. Other features and advantages are described herein.

Abstract: In an example, there is disclosed a computing apparatus, including one or more logic elements, including at least one hardware logic element, comprising a classification engine to: receive a clean multi-labeled dataset comprising a plurality of document each assigned to one or more of a plurality of categories; receive an unclean multi-labeled dataset; and produce a recategorized and cleansed dataset from the unclean multi-labeled dataset, comprising predicting a number of labels {circumflex over (l)} for a document j, and comparing {circumflex over (l)} to an existing number of labels l. There is also disclosed a method of providing a classification engine.

Abstract: In an example, there is disclosed a computing apparatus, including one or more logic elements comprising a classification engine operable to identify at least one overlapping class pair comprising at least two classes selected from a class group, wherein the overlapping class pair may be characterized by a substantial mutual false positive rate; and assign an object to at least one assigned class selected from the class group.

Abstract: One embodiment of the present invention sets forth a technique for broadcasting composited game content. The technique includes executing an application program to generate a first video frame of game content, and causing the first video frame to be displayed on a primary display device. The technique further includes compositing at least one graphical user interface (GUI) element with the first video frame to generate a composited frame. The technique further includes causing the composited frame to be displayed on an external display device by transmitting the composited frame to the external display device via a local display interface.

Abstract: The present invention relates to substituted aryl naphthyl methanone oximes of general formula (I), their process for preparation and their derivatives, salts, pharmaceutical composition thereof and their use in treatment of chronic myelogenous leukemia, acute myelogenous leukemia, lymphoma, multiple myeloma, solid tumor forming cell-lines including such as breast cancer, endometrial cancer colon cancer, prostate cancer and killing of drug resistant cancer stem cells, as subject in need thereof.

Abstract: Permanent magnets are used for several important applications, including dc electrical motors, wind turbines, hybrid automobile, and for many other applications. Modern widely used rare-earth based permanent magnet materials, such as Sm—Co and Nd—Fe—B, are generally intermetallic alloys made from rare earth elements and transition metals such as cobalt. However, the high costs of rare earth elements make the widespread use of these permanent magnets commercially unattractive. The present work focuses on producing a new permanent magnet material, with good magnetic properties, which is free from rare-earth elements and thus cost-effective. The present invention provides a process to synthesis boron doped manganese antimonide as an alternative to rare earth based permanent magnet materials. The boron doped manganese antimonide disclosed in this invention is free from rare-earth element with good magnetic properties.

Abstract: Particular embodiments described herein provide for an electronic device that can be configured to analyze data to determine one or more unique topics for a first class and one or more common topics that are common with the first class and a second class, where the topics that are common with the first class and the second class include one or more subtopics, assign one or more classifications to the data based, at least in part, on the one or more subtopics, and store the one or more classifications assigned to the data in memory. The one or more unique topics and one or more common topics can be determined by using a Jaccard Index. Also, the one or more subtopics can be determined using Latent Dirichlet Allocation.

Abstract: Particular embodiments described herein provide for an electronic device that can be configured to analyze data using an ensemble and assign a classification to the data based, at least in part, on the results of the analyses using the ensemble. The ensemble can include one or more multinomial classifiers and each multinomial classifier can assign two or more classifications to the data.

Abstract: In an example, there is disclosed a computing apparatus, including one or more logic elements, including at least one hardware logic element, comprising a classification engine to: receive a clean multi-labeled dataset comprising a plurality of document each assigned to one or more of a plurality of categories; receive an unclean multi-labeled dataset; and produce a recategorized and cleansed dataset from the unclean multi-labeled dataset, comprising predicting a number of labels {circumflex over (l)} for a document j, and comparing {circumflex over (l)} to an existing number of labels l. There is also disclosed a method of providing a classification engine.

Abstract: In an example, there is disclosed a computing apparatus, including one or more logic elements comprising a classification engine operable to identify at least one overlapping class pair comprising at least two classes selected from a class group, wherein the overlapping class pair may be characterized by a substantial mutual false positive rate; and assign an object to at least one assigned class selected from the class group.

Abstract: Methods and systems for dynamically training a web crawler. The web crawler maintains one or more categories each comprising a set of words. The method includes selecting at least one hyperlink in response to a query received from a user. The method further includes determining a hyperlink score for the at least one hyperlink based on a category score associated with each of one or more categories. The category score associated with each of the one or more categories is updated based at least in part on the hyperlink score. The updated category score is compared with the hyperlink score to select a category from the one or more categories. The set of words associated with the category is updated based on content of a web page pointed by the at least one hyperlink.

Abstract: A method, non-transitory computer readable medium, and apparatus for predicting a location of a short text are disclosed. For example, the method trains a model for each parent node of a grid of a plurality of parent nodes of a geographical area using a plurality of previously received short texts having a known location, receives the short text, applies a hierarchical modeling algorithm to the short text to calculate a weighted probability for one or more child nodes of one or more of the plurality of parent nodes and predicts the location of the short text within the grid of the geographical area based upon a child node of the one or more child nodes having a highest weighted probability.

Abstract: The present invention relates to substituted aryl naphthyl methanone oximes of general formula (I), their process for preparation and their derivatives, salts, pharmaceutical composition thereof and their use in treatment of chronic myelogenous leukemia, acute myelogenous leukemia, lymphoma, multiple myeloma, solid tumor forming cell- lines including such as breast cancer, endometrial cancer colon cancer, prostate cancer and killing of drug resistant cancer stem cells, as subject in need thereof.

Abstract: The present invention relates to ulmoside A as a novel small molecule adiponectin receptor agonist useful for prevention or cure of metabolic diseases. The present invention further relates to the use of ulmoside-A (ULMA) ((2S,3S)-(+)-3?,4?,5,7-tetrahydroxydihydroflavonol-6-C-?-D-glucopyranoside) for alleviation, management or prevention or treatment of steroid-induced metabolic disorder. The present invention further relates to a pharmaceutical composition useful for prevention and/or treatment of various medical indications associated with metabolic diseases caused in humans and animals.

Abstract: Online learning of an ensemble of classifiers or regressors is performed to predict a non-stationary time-varying parameter over a time series of episodes. For an episode, an ensemble action is selected from a set of ensemble actions based on ensemble action quality values (Q values) at an error state for the episode. The selected ensemble action is executed to update the ensemble. A cost of executing the selected ensemble action is computed or retrieved, and a reward is computed indicating how well the updated ensemble predicts the non-stationary time-varying parameter over the episode. The Q value for the selected ensemble action at the error state for the episode is updated based on both the reward and the cost of executing the selected ensemble action. The cost may be based on the ensemble action alone, or on both the ensemble action and the error state for the episode.

Abstract: A method, non-transitory computer readable medium, and apparatus for predicting a location of a short text are disclosed. For example, the method trains a model for each parent node of a grid of a plurality of parent nodes of a geographical area using a plurality of previously received short texts having a known location, receives the short text, applies a hierarchical modeling algorithm to the short text to calculate a weighted probability for one or more child nodes of one or more of the plurality of parent nodes and predicts the location of the short text within the grid of the geographical area based upon a child node of the one or more child nodes having a highest weighted probability.

Abstract: A web page identified by a URL stored in a downloads queue is downloaded, and hyperlinks in the downloaded web page are identified. Each hyperlink is screened by parsing the hyperlink (optionally only the URL of the hyperlink) to identify features comprising character strings, computing for each feature values for one or more meta-features indicative of the hyperlinked web page being in a target language, aggregating the meta-feature values to generate a score for the hyperlink, and adding the URL of the hyperlink to the downloads queue conditional upon the score satisfying a screening criterion. The downloading, identifying, and screening are iteratively repeated to perform web crawling, and an index of web pages in the target language is constructed based on analysis of content of the downloaded web pages. The meta-features may include a transliterated target word meta-feature, a language code meta-feature, a country code meta-feature, or so forth.

Abstract: One embodiment of the present invention sets forth a technique for broadcasting composited game content. The technique includes executing an application program to generate a first video frame of game content, and causing the first video frame to be displayed on a primary display device. The technique further includes compositing at least one graphical user interface (GUI) element with the first video frame to generate a composited frame.