Patents by Inventor Niels Abrahamsen

Niels Abrahamsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical compositions for treatment of HCV patients that are poor-responders to interferon
    Patent number: 9034837
    Abstract: The present invention provides compositions and methods of treatment of HCV infected subjects that are not sensitive to interferon treatment. Further, compositions and methods are provided for prevention of organ transplant rejection. The compositions of the invention comprise an anti microRNA-122 oligonucleotide, and are made for administration to a primate.
    Type: Grant
    Filed: April 26, 2010
    Date of Patent: May 19, 2015
    Assignee: Roche Innovation Center Copenhagen A/S
    Inventors: Elisabeth S. Hildebrandt-Eriksen, Andreas Petri, Sakari Kauppinen, Niels Abrahamsen, Robert Eldon Lanford
  • Pharmaceutical compositions for treatment of MicroRNA related diseases
    Patent number: 8404659
    Abstract: The present invention provides compositions and methods of treatment of diseases that are sensitive to drugs that downregulate the function of microRNA's, mRNA, non-coding RNA, or viral genomes. In particular, it has been discovered that a very long term effect of an anti microRNA oligonucleotide may be obtained when administered to a primate. Therefore, the present invention relate to pharmaceutical compositions and methods for treatment of primates, including humans wherein the compositions are administered with a long time interval.
    Type: Grant
    Filed: March 9, 2009
    Date of Patent: March 26, 2013
    Assignee: Santaris Pharma A/S
    Inventors: Sakari Kauppinen, Niels Abrahamsen, Elisabeth S. Hildebrandt-Eriksen, Martin Munk
  • Pharmaceutical compositions for treatment of microRNA related diseases
    Patent number: 8361980
    Abstract: The present invention provides compositions and methods of treatment of diseases that are sensitive to drugs that downregulate the function of microRNA's, mRNA, non-coding RNA, or viral genomes. In particular, it has been discovered that a very long term effect of an anti microRNA oligonucleotide may be obtained when administered to a primate. Therefore, the present invention relate to pharmaceutical compositions and methods for treatment of primates, including humans wherein the compositions are administered with a long time interval.
    Type: Grant
    Filed: March 9, 2009
    Date of Patent: January 29, 2013
    Assignee: Santaris Pharma A/S
    Inventors: Sakari Kauppinen, Niels Abrahamsen, Elisabeth Hildebrandt-Eriksen, Martin Munk
  • Pharmaceutical Compositions for Treatment of MicroRNA Related Diseases
    Publication number: 20110077288
    Abstract: The present invention provides compositions and methods of treatment of diseases that are sensitive to drugs that downregulate the function of microRNA's, mRNA, non-coding RNA, or viral genomes. In particular, it has been discovered that a very long term effect of an anti microRNA oligonucleotide may be obtained when administered to a primate. Therefore, the present invention relate to pharmaceutical compositions and methods for treatment of primates, including humans wherein the compositions are administered with a long time interval.
    Type: Application
    Filed: March 9, 2009
    Publication date: March 31, 2011
    Applicant: Santaris Pharma A/S
    Inventors: Sakari Kauppinen, Niels Abrahamsen, Elisabeth Hildebrandt-Eriksen, Martin Munk
  • Pharmaceutical Compositions for Treatment of HCV Patients that are Poor-Responders to Interferon
    Publication number: 20100330035
    Abstract: The present invention provides compositions and methods of treatment of HCV infected subjects that are not sensitive to interferon treatment. Further, compositions and methods are provided for prevention of organ transplant rejection. The compositions of the invention comprise an anti microRNA-122 oligonucleotide, and are made for administration to a primate.
    Type: Application
    Filed: April 26, 2010
    Publication date: December 30, 2010
    Inventors: Elisabeth S. HILDEBRANDT-ERIKSEN, Andreas Petri, Sakari Kauppinen, Niels Abrahamsen, Robert Eldon Lanford
  • Pharmaceutical compositions for treatment of microRNA related diseases
    Publication number: 20090298916
    Abstract: The present invention provides compositions and methods of treatment of diseases that are sensitive to drugs that downregulate the function of microRNA's, mRNA, non-coding RNA, or viral genomes. In particular, it has been discovered that a very long term effect of an anti microRNA oligonucleotide may be obtained when administered to a primate. Therefore, the present invention relate to pharmaceutical compositions and methods for treatment of primates, including humans wherein the compositions are administered with a long time interval.
    Type: Application
    Filed: March 9, 2009
    Publication date: December 3, 2009
    Applicant: Santaris Pharma A/S
    Inventors: Sakari Kauppinen, Niels Abrahamsen, Elisabeth Hildebrandt-Eriksen, Martin Munk