Patents by Inventor Niels Agersnap Larsen
Niels Agersnap Larsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230341318Abstract: A method and a system for analyzing a fluid sample for a biological activity. The method includes, providing a filter unit including a membrane having a front face and a rear face, passing the fluid sample through the filter membrane from its front face, applying the filter unit in a container, adding a medium into the container, and performing a scanning and image analyzing procedure of the filter membrane using at least one selected scanning wavelength. The scanning is an optical 3D scanning and includes acquiring a plurality of images along at least one scanning path.Type: ApplicationFiled: November 27, 2020Publication date: October 26, 2023Applicant: INTUBIO APSInventors: Tom OLESEN, Niels Agersnap LARSEN
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Patent number: 10782306Abstract: The invention relates to a method of determining a concentration of a substance in a cell suspension, said method comprising the following steps: —determining the concentration of the substance by: —using the results of absorption measurements performed at n local sample volumes contained at different average chamber heights of a chamber arrangement comprising the cell suspension and local substance concentration in said respective local sample volumes determined based on said respective absorption measurements; —using a substance concentration model comprising local substance concentration as a function of chamber height, and—determining the substance concentration as the infinite chamber height substance concentration using said substance concentration model and the determined local substance concentrations, wherein n is at least 2, such as at least 3, such as at least 4, wherein, optionally, the cell suspension is whole blood and the substance is Hb and wherein the method further comprises determining cRBCType: GrantFiled: December 22, 2016Date of Patent: September 22, 2020Assignee: KONINKLIJKE PHILIPS N.V.Inventor: Niels Agersnap Larsen
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Patent number: 10549480Abstract: The invention is about an ultrasonic welding-based microfluidic device. It is mainly made of a first element and a second element welded one to the other via at least one structure (10, 10?). The structure (10, 10?) comprises an elongated welded portion for said welding, a welding channel (12, 12?) extending between the first and second elements and along one side of the welded portion, and a draining channel (13) communicating with the welding channel (12, 12?) and the microfluidic path (20, 20?) of the device. The invention is further about a method of manufacturing such a device.Type: GrantFiled: November 17, 2017Date of Patent: February 4, 2020Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Niels Agersnap Larsen, Klaus Mogensen
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Publication number: 20190310189Abstract: An apparatus (100), a method and a cartridge (10) for determining a refractive index (ns) of a sample (12) are provided. The apparatus (100) comprises a cartridge (10) for receiving the sample (12) and an imaging unit (102) comprising a light source (104) for irradiating the cartridge (10) with a light beam (106), an image sensor (108) for capturing an image (122a) of said part of the cartridge (10), an objective lens (114), and a processing module (116) for analyzing the captured image (122a). The cartridge (10) comprises an optical element (20) configured to refract and/or diffract the light beam (106), wherein the objective lens (114) is arranged to receive the refracted and/or diffracted part of the light beam (106).Type: ApplicationFiled: December 8, 2017Publication date: October 10, 2019Inventor: Niels Agersnap LARSEN
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Patent number: 10430640Abstract: A particle classifier system and a method of training the system are described.Type: GrantFiled: December 24, 2018Date of Patent: October 1, 2019Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Martin Christian Valvik, Niels Agersnap Larsen, Tommy Winther Berg
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Publication number: 20190270255Abstract: The invention is about an ultrasonic welding-based microfluidic device. It is mainly made of a first element and a second element welded one to the other via at least one structure (10, 10?). The structure (10, 10?) comprises an elongated welded portion for said welding, a welding channel (12, 12?) extending between the first and second elements and along one side of the welded portion, and a draining channel (13) communicating with the welding channel (12, 12?) and the microfluidic path (20, 20?) of the device. The invention is further about a method of manufacturing such a device.Type: ApplicationFiled: November 17, 2017Publication date: September 5, 2019Inventors: Niels Agersnap LARSEN, Klaus MOGENSEN
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Publication number: 20190130162Abstract: A particle classifier system and a method of training the system are described.Type: ApplicationFiled: December 24, 2018Publication date: May 2, 2019Inventors: Martin Christian VALVIK, Niels Agersnap LARSEN, Tommy Winther BERG
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Patent number: 10192100Abstract: A particle classifier system and a method of training the system are described.Type: GrantFiled: February 2, 2018Date of Patent: January 29, 2019Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Martin Christian Valvik, Niels Agersnap Larsen, Tommy Winther Berg
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Publication number: 20180372758Abstract: The invention relates to a method of determining a concentration of a substance in a cell suspension, said method comprising the following steps: —determining the concentration of the substance by: —using the results of absorption measurements performed at n local sample volumes contained at different average chamber heights of a chamber arrangement comprising the cell suspension and local substance concentration in said respective local sample volumes determined based on said respective absorption measurements; —using a substance concentration model comprising local substance concentration as a function of chamber height, and—determining the substance concentration as the infinite chamber height substance concentration using said substance concentration model and the determined local substance concentrations, wherein n is at least 2, such as at least 3, such as at least 4, wherein, optionally, the cell suspension is whole blood and the substance is Hb and wherein the method further comprises determining cRBCType: ApplicationFiled: December 22, 2016Publication date: December 27, 2018Inventor: Niels Agersnap LARSEN
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Publication number: 20180156422Abstract: A radiation emitting element comprising a radiation transmissive element having a first refractive index, a first surface, a second, opposite surface, a radiation emitter adapted to emit radiation of a predetermined wavelength into the radiation transmissive element, and a plurality of radiation controlling elements, wherein each radiation controlling element comprises: a first liquid having a second refractive index, a second fluid having a third refractive index being lower than the second refractive index, the second refractive index being closer to the first refractive index than the third refractive index, means for altering a shape of the first liquid between two modes wherein: in a first mode, the first liquid being in contact with the first surface at a first surface part, and an interface between the first liquid and the second fluid, at the first surface part, is not parallel to the first surface part and in a second mode, a surface of the second fluid, at the first surface part, is at least suType: ApplicationFiled: June 30, 2017Publication date: June 7, 2018Inventors: Jens Ostergaard, Niels Agersnap LARSEN
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Publication number: 20180157894Abstract: A particle classifier system and a method of training the system are described.Type: ApplicationFiled: February 2, 2018Publication date: June 7, 2018Inventors: Martin Christian VALVIK, Niels Agersnap LARSEN, Tommy Winther BERG
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Patent number: 9915813Abstract: The invention relates to a system and a method for determination of a value for at least one parameter describing microbial activity of individual biological organisms in a liquid sample. Images, wherein individual biological organisms may be identified, are combined to provide optical sectionings of the biological organisms and the optical sectionings are analyzed to determine the value for said at least one parameter describing microbial activity of said individual biological organisms in each sample container.Type: GrantFiled: December 1, 2010Date of Patent: March 13, 2018Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Tom Olesen, Martin Christian Valvik, Niels Agersnap Larsen
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Patent number: 9904842Abstract: A particle classifier system and a method of training the system are described.Type: GrantFiled: December 19, 2013Date of Patent: February 27, 2018Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Martin Christian Valvik, Niels Agersnap Larsen, Tommy Winther Berg
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Patent number: 9841593Abstract: An apparatus for obtaining a plurality of images of a sample includes a sample device suitable for holding a liquid sample; a first optical detection assembly including a first image acquisition device, the first optical detection assembly having an optical axis and an object plane, the object plane including an image acquisition area from which electromagnetic waves can be detected as an image by the first image acquisition device; one translation unit arranged to move the sample device and the first optical detection assembly relative to each other; and an image illumination device, wherein the apparatus is arranged to move the sample device and the first optical detection assembly relative to each other along a scanning path, which defines an angle theta relative to the optical axis, wherein theta is in the range of about 0.3 to about 89.7 degrees.Type: GrantFiled: June 9, 2014Date of Patent: December 12, 2017Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Tom Olesen, Martin Christian Valvik, Niels Agersnap Larsen, Rasmus Helmsby Sandberg
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Patent number: 9696014Abstract: A radiation emitting element comprising a radiation transmissive element having a first refractive index, a first surface, a second, opposite surface, a radiation emitter adapted to emit radiation of a predetermined wavelength into the radiation transmissive element, and a plurality of radiation controlling elements, wherein each radiation controlling element comprises: a first liquid having a second refractive index, a second fluid having a third refractive index being lower than the second refractive index, the second refractive index being closer to the first refractive index than the third refractive index, means for altering a shape of the first liquid between two modes wherein: • in a first mode, the first liquid being in contact with the first surface at a first surface part, and an interface between the first liquid and the second fluid, at the first surface part, is not parallel to the first surface part and • in a second mode, a surface of the second fluid, at the first surface part, is at least subType: GrantFiled: September 4, 2015Date of Patent: July 4, 2017Assignee: BLACKBRITE APSInventors: Jens Wagenblast Stubbe Østergaard, Niels Agersnap Larsen
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Publication number: 20150377454Abstract: A radiation emitting element comprising a radiation transmissive element having a first refractive index, a first surface, a second, opposite surface, a radiation emitter adapted to emit radiation of a predetermined wavelength into the radiation transmissive element, and a plurality of radiation controlling elements, wherein each radiation controlling element comprises: a first liquid having a second refractive index, a second fluid having a third refractive index being lower than the second refractive index, the second refractive index being closer to the first refractive index than the third refractive index, means for altering a shape of the first liquid between two modes wherein: in a first mode, the first liquid being in contact with the first surface at a first surface part, and an interface between the first liquid and the second fluid, at the first surface part, is not parallel to the first surface part and in a second mode, a surface of the second fluid, at the first surface part, is at least substanType: ApplicationFiled: September 4, 2015Publication date: December 31, 2015Applicant: BLACKBRITE APSInventors: Jens Wagenblast Stubbe ØSTERGAARD, Niels Agersnap LARSEN
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Publication number: 20150347817Abstract: A particle classifier system and a method of training the system are described.Type: ApplicationFiled: December 19, 2013Publication date: December 3, 2015Inventors: MARTIN CHRISTIAN VALVIK, NIELS AGERSNAP LARSEN, TOMMY WINTHER BERG
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Patent number: 9176342Abstract: A radiation emitting element comprising a radiation transmissive element having a first refractive index, a first surface, a second, opposite surface, a radiation emitter adapted to emit radiation of a predetermined wavelength into the radiation transmissive element, and a plurality of radiation controlling elements, wherein each radiation controlling element comprises: a first liquid having a second refractive index, a second fluid having a third refractive index being lower than the second refractive index, the second refractive index being closer to the first refractive index than the third refractive index, means for altering a shape of the first liquid between two modes wherein: • in a first mode, the first liquid being in contact with the first surface at a first surface part, and an interface between the first liquid and the second fluid, at the first surface part, is not parallel to the first surface part and • in a second mode, a surface of the second fluid, at the first surface part, is at least subType: GrantFiled: September 26, 2013Date of Patent: November 3, 2015Assignee: Blackbrite APSInventors: Jens Wagenblast Stubbe Østergaard, Niels Agersnap Larsen
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Patent number: 9063617Abstract: An interactive display system that may be implemented to provide an electronic whiteboard that enables users to input information to the system by engaging a display with one or more objects. The system may present an image via the display that reflects the inputs received from the user. For example, the display may be dynamically updated to mimic inputs made to a whiteboard by the user via one or more pens and/or an eraser. The interactive display system may implement an underlayer embedded within the display to guide electromagnetic radiation that emanates from an object engaged with the display to one or more detectors by total internal reflection. Due at least in part to the efficiency of the underlayer in guiding the electromagnetic radiation to the detectors, the interactive display system may enhance the speed and/or accuracy of the interpretation of the inputs made by the user.Type: GrantFiled: October 16, 2006Date of Patent: June 23, 2015Assignee: FlatFrog Laboratories ABInventors: Jonas Ove Philip Eliasson, Niels Agersnap Larsen, Jens Bastue, Jens Wagenblast Stubbe Østergaard
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Publication number: 20140347447Abstract: An apparatus for obtaining a plurality of images of a sample includes a sample device suitable for holding a liquid sample; a first optical detection assembly including a first image acquisition device, the first optical detection assembly having an optical axis and an object plane, the object plane including an image acquisition area from which electromagnetic waves can be detected as an image by the first image acquisition device; one translation unit arranged to move the sample device and the first optical detection assembly relative to each other; and an image illumination device, wherein the apparatus is arranged to move the sample device and the first optical detection assembly relative to each other along a scanning path, which defines an angle theta relative to the optical axis, wherein theta is in the range of about 0.3 to about 89.7 degrees.Type: ApplicationFiled: June 9, 2014Publication date: November 27, 2014Applicant: UNISENSOR A/SInventors: Tom OLESEN, Martin Christian VALVIK, Niels Agersnap LARSEN, Rasmus Helmsby SANDBERG