Patents by Inventor Niels Borgstein

Niels Borgstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTAGONISTS OF ACTIVIN-ACTRIIA AND USES FOR INCREASING RED BLOOD CELL LEVELS
    Publication number: 20220204576
    Abstract: In certain aspects, the present invention provides compositions and methods for increasing red blood cell and/or hemoglobin levels in vertebrates, including rodents and primates, and particularly in humans.
    Type: Application
    Filed: August 5, 2021
    Publication date: June 30, 2022
    Inventors: Matthew L. Sherman, Jasbir Seehra, Niels Borgstein
  • METHODS FOR DOSING AN ACTRIIB ANTAGONIST AND MONITORING OF TREATED PATIENTS
    Publication number: 20220118049
    Abstract: In certain aspects, the present invention provides methods for dosing a patient with an ActRIIb antagonist and methods for managing patients treated with an ActRIIb anatagonist. In certain aspects, the methods involve measuring one or more hematologic parameters in a patient.
    Type: Application
    Filed: May 27, 2021
    Publication date: April 21, 2022
    Inventors: Matthew L. Sherman, Niels Borgstein
  • ANTAGONISTS OF ACTIVIN-ACTRIIA AND USES FOR INCREASING RED BLOOD CELL LEVELS
    Publication number: 20210355181
    Abstract: In certain aspects, the present invention provides compositions and methods for increasing red blood cell and/or hemoglobin levels in vertebrates, including rodents and primates, and particularly in humans.
    Type: Application
    Filed: December 23, 2020
    Publication date: November 18, 2021
    Inventors: Matthew L. Sherman, Jasbir Seehra, Niels Borgstein
  • METHODS FOR DOSING AN ACTIVIN-ACTRIIA ANTAGONIST AND MONITORING OF TREATED PATIENTS
    Publication number: 20210038689
    Abstract: In certain aspects, the present invention provides methods for dosing a patient with an activin-ActRIIa antagonist and methods for managing patients treated with an activin-ActRIIa antagonist. In certain aspects, the methods involve measuring one or more hematologic parameters in a patient.
    Type: Application
    Filed: March 17, 2020
    Publication date: February 11, 2021
    Inventors: Matthew Sherman, Niels Borgstein
  • ANTAGONISTS OF ACTRIIB AND USES FOR INCREASING RED BLOOD CELL LEVELS
    Publication number: 20200255495
    Abstract: In certain aspects, the present invention provides compositions and methods for increasing red blood cell and/or hemoglobin levels in vertebrates, including rodents and primates, and particularly in humans.
    Type: Application
    Filed: September 13, 2019
    Publication date: August 13, 2020
    Inventors: Matthew L. Sherman, Jasbir Seehra, Niels Borgstein
  • ANTAGONISTS OF ACTIVIN-ACTRIIA AND USES FOR INCREASING RED BLOOD CELL LEVELS
    Publication number: 20190225664
    Abstract: In certain aspects, the present invention provides compositions and methods for increasing red blood cell and/or hemoglobin levels in vertebrates, including rodents and primates, and particularly in humans.
    Type: Application
    Filed: September 4, 2018
    Publication date: July 25, 2019
    Inventors: Matthew L. Sherman, Jasbir Seehra, Niels Borgstein
  • Antagonists of activin-ActRIIa and uses for increasing red blood cell levels
    Patent number: 10093707
    Abstract: In certain aspects, the present invention provides compositions and methods for increasing red blood cell and/or hemoglobin levels in vertebrates, including rodents and primates, and particularly in humans.
    Type: Grant
    Filed: November 20, 2014
    Date of Patent: October 9, 2018
    Assignee: ACCELERON PHARMA INC.
    Inventors: Matthew L. Sherman, Jasbir Seehra, Niels Borgstein
  • ANTAGONISTS OF ACTRIIB AND USES FOR INCREASING RED BLOOD CELL LEVELS
    Publication number: 20180009872
    Abstract: In certain aspects, the present invention provides compositions and methods for increasing red blood cell and/or hemoglobin levels in vertebrates, including rodents and primates, and particularly in humans.
    Type: Application
    Filed: July 18, 2017
    Publication date: January 11, 2018
    Inventors: Matthew L. Sherman, Jasbir Seehra, Niels Borgstein
  • METHODS FOR DOSING AN ACTRIIB ANTAGONIST AND MONITORING OF TREATED PATIENTS
    Publication number: 20160279197
    Abstract: In certain aspects, the present invention provides methods for dosing a patient with an ActRIIb antagonist and methods for managing patients treated with an ActRIIb anatagonist. In certain aspects, the methods involve measuring one or more hematologic parameters in a patient.
    Type: Application
    Filed: January 25, 2016
    Publication date: September 29, 2016
    Inventors: Matthew L. Sherman, Niels Borgstein
  • METHODS FOR DOSING AN ACTIVIN-ACTRIIA ANTAGONIST AND MONITORING OF TREATED PATIENTS
    Publication number: 20160279203
    Abstract: In certain aspects, the present invention provides methods for dosing a patient with an activin-ActRIIa antagonist and methods for managing patients treated with an activin-ActRIIa anatagonist. In certain aspects, the methods involve measuring one or more hematologic parameters in a patient.
    Type: Application
    Filed: January 25, 2016
    Publication date: September 29, 2016
    Inventors: Matthew L. Sherman, Niels Borgstein
  • ANTAGONISTS OF ACTIVIN-ACTRIIA AND USES FOR INCREASING RED BLOOD CELL LEVELS
    Publication number: 20150183845
    Abstract: In certain aspects, the present invention provides compositions and methods for increasing red blood cell and/or hemoglobin levels in vertebrates, including rodents and primates, and particularly in humans.
    Type: Application
    Filed: November 20, 2014
    Publication date: July 2, 2015
    Inventors: Matthew L. Sherman, Jasbir Seehra, Niels Borgstein
  • Follistatin Fusion Proteins and Uses Thereof
    Publication number: 20150158923
    Abstract: In certain aspects, the present invention provides methods for dosing a patient with an ActRIIb antagonist and methods for managing patients treated with an ActRIIb anatagonist. In certain aspects, the methods involve measuring one or more hematologic parameters in a patient.
    Type: Application
    Filed: February 13, 2015
    Publication date: June 11, 2015
    Inventors: Matthew L. Sherman, Niels Borgstein
  • Antagonists of activin-actriia and uses for increasing red blood cell levels
    Patent number: 8895016
    Abstract: In certain aspects, the present invention provides compositions and methods for increasing red blood cell and/or hemoglobin levels in vertebrates, including rodents and primates, and particularly in humans.
    Type: Grant
    Filed: June 26, 2009
    Date of Patent: November 25, 2014
    Assignee: Acceleron Pharma, Inc.
    Inventors: Matthew L. Sherman, Jasbir Seehra, Niels Borgstein
  • ANTAGONISTS OF ACTRIIB AND USES FOR INCREASING RED BLOOD CELL LEVELS
    Publication number: 20120003218
    Abstract: In certain aspects, the present invention provides compositions and methods for increasing red blood cell and/or hemoglobin levels in vertebrates, including rodents and primates, and particularly in humans.
    Type: Application
    Filed: August 25, 2011
    Publication date: January 5, 2012
    Applicant: Acceleron Pharma Inc.
    Inventors: Matthew L. Sherman, Jasbir Seehra, Niels Borgstein
  • Antagonists of activin-actriia and uses for increasing red blood cell levels
    Publication number: 20100028331
    Abstract: In certain aspects, the present invention provides compositions and methods for increasing red blood cell and/or hemoglobin levels in vertebrates, including rodents and primates, and particularly in humans.
    Type: Application
    Filed: June 26, 2009
    Publication date: February 4, 2010
    Applicant: Acceleron Pharma Inc.
    Inventors: Matthew L. Sherman, Jasbir Seehra, Niels Borgstein
  • Antagonists of actriib and uses for increasing red blood cell levels
    Publication number: 20100028332
    Abstract: In certain aspects, the present invention provides compositions and methods for increasing red blood cell and/or hemoglobin levels in vertebrates, including rodents and primates, and particularly in humans.
    Type: Application
    Filed: June 26, 2009
    Publication date: February 4, 2010
    Applicant: Acceleron Pharma Inc.
    Inventors: Matthew L. Sherman, Jasbir Seehra, Niels Borgstein
  • Methods for dosing an activin-actriia antagonist and monitoring of treated patients
    Publication number: 20100015144
    Abstract: In certain aspects, the present invention provides methods for dosing a patient with an activin-ActRIIa antagonist and methods for managing patients treated with an activin-ActRIIa anatagonist. In certain aspects, the methods involve measuring one or more hematologic parameters in a patient.
    Type: Application
    Filed: June 26, 2009
    Publication date: January 21, 2010
    Applicant: Acceleron Pharma Inc.
    Inventors: Matthew L. Sherman, Niels Borgstein
  • Methods for dosing an actriib antagonist and monitoring of treated patients
    Publication number: 20100008918
    Abstract: In certain aspects, the present invention provides methods for dosing a patient with an ActRIIb antagonist and methods for managing patients treated with an ActRIIb anatagonist. In certain aspects, the methods involve measuring one or more hematologic parameters in a patient.
    Type: Application
    Filed: June 26, 2009
    Publication date: January 14, 2010
    Applicant: Acceleron Pharma Inc.
    Inventors: Matthew L. Sherman, Niels Borgstein