Patents by Inventor Niels Brunner

Niels Brunner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SUPPRESSION OF INHIBITORS
    Publication number: 20080166354
    Abstract: The present invention relates to methods for inhibiting malignant tumour growth, invasion and/or metastasis in a patient, the method comprising suppressing the inhibitory activity of an inhibitor of a protease or of a non-proteolytic matrix-degrading enzyme (IPNME) in malignant tumour tissue or potential malignant tumour tissue. The suppression may be brought about by administering compounds interacting with the IPNME, but also administration of compounds interacting with transcription of genes encoding the IPNME is a possibility. The invention also relates to methods of selecting and identifying compounds in the therapeutical methods, as well of the use of such compounds in the treatment of malignancies.
    Type: Application
    Filed: December 26, 2007
    Publication date: July 10, 2008
    Inventors: Niels Brunner, John Romer, Vincent Ellis, Charles Pyke, Jan Grondahl-Hansen, Helle Pedersen Pappot, Heine Hoi Hansen, Keld Dano
  • Suppression of inhibitors
    Publication number: 20030096755
    Abstract: The present invention relates to methods for inhibiting malignant tumour growth, invasion and/or metastasis in a patient, the method comprising suppressing the inhibitory activity of an inhibitor of a protease or of a non-proteolytic matrix-degrading enzyme (IPNME) in malignant tumour tissue or potential malignant tumour tissue. The suppression may be brought about by administering compounds interacting with the IPNME, but also administration of compounds interacting with transcription of genes encoding the IPNME is a possibility. The invention also relates to methods of selecting and identifying compounds in the therapeutical methods, as well of the use of such compounds in the treatment of malignancies.
    Type: Application
    Filed: January 2, 2003
    Publication date: May 22, 2003
    Inventors: Niels Brunner, John Romer, Vincent Ellis, Charles Pyke, Jan Grondahl-Hansen, Helle Pedersen Pappot, Heine Hoi Hansen, Keld Dano
  • Suppression of inhibitors
    Publication number: 20010034327
    Abstract: The present invention relates to methods for inhibiting malignant tumour growth, invasion and/or metastasis in a patient, the method comprising suppressing the inhibitory activity of an inhibitor of a protease or of a non-proteolytic matrix-degrading enzyme (IPNME) in malignant tumour tissue or potential malignant tumour tissue. The suppression may be brought about by administering compounds interacting with the IPNME, but also administration of compounds interacting with transcription of genes encoding the IPNME is a possibility. The invention also relates to methods of selecting and identifying compounds in the therapeutical methods, as well of the use of such compounds in the treatment of malignancies.
    Type: Application
    Filed: April 18, 2001
    Publication date: October 25, 2001
    Inventors: Niels Brunner, John Romer, Vincent Ellis, Charles Pyke, Jan Grondahl-Hansen, Helle Pedersen Pappot, Heine Hoi Hansen, Keld Dano