Patents by Inventor Niels Peter Hundahl M.o slashed.ller

Niels Peter Hundahl M.o slashed.ller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modulators of molecules with phosphotyrosine recognition units
    Patent number: 6043247
    Abstract: The present invention relates to novel substituted acrylic acids, to methods for their preparation, compositions containing them, and their use for treatment of human and animal disorders, to their use for purification of proteins or glycoproteins, and to their use in diagnosis. The invention also relates to modulation of the activity of molecules with phospho-tyrosine recognition units, including protein tyrosine phosphatases (PTPases) and proteins with Src-homology-2 domains, in in vitro systems, microorganisms, eukaryotic cells, whole animals and human beings.
    Type: Grant
    Filed: April 16, 1997
    Date of Patent: March 28, 2000
    Assignee: Novo Nordisk A/S
    Inventors: Henrik Sune Andersen, Niels Peter Hundahl M.o slashed.ller, Peter Madsen
  • Nucleic acid encoding novel protein phosphotyrosine phosphatase PTP-D1
    Patent number: 5955592
    Abstract: The present invention relates to PTP-D1, a member of the novel PTP-D subfamily of protein tyrosine phosphatases. The present invention is directed to isolated PTP-D1 protein, nucleic acid constructs encoding for PTP-D1, cells containing the nucleic acid constructs, and methods for production and identification of PTP-D1. Antibodies to PTP-D1 protein and methods for screening molecules which can bind to PTP-D1 protein or inhibit or stimulate the protein-tyrosine phosphatase enzymatic activity of PTP-D1, are also provided.
    Type: Grant
    Filed: April 27, 1994
    Date of Patent: September 21, 1999
    Assignee: Max Planck Gesellschaft zur Forderung der Wissenschaften e.V.
    Inventors: Axel Ullrich, Niels Peter Hundahl M.o slashed.ller, Karin Bach M.o slashed.ller
  • Methods for identifying modulators of insulin receptor phosphorylation
    Patent number: 5856111
    Abstract: The present invention relates to cell lines useful for the screening and identification of compounds that by modulating phosphotyrosine phosphatase activity, modulate insulin receptor type tyrosine kinase mediated signal transduction. Genetically engineered cells expressing IR in culture overcome the effect of insulin on morphology and adhesion when they are also coexpressing RPTP.alpha. or RPTP.epsilon.. Such engineered cell lines may be used to screen and identify non-toxic compounds that could elicit or modulate insulin signal transduction even in the absence of insulin.
    Type: Grant
    Filed: November 18, 1996
    Date of Patent: January 5, 1999
    Assignee: Max-Planck-Gessellschaft Zur Forderung der Wissenschaften E.V.
    Inventors: Axel Ullrich, Edmund Hoppe, Niels Peter Hundahl M.o slashed.ller
  • Protein phosphotyrosine phosphatases PTP-D1
    Patent number: 5831009
    Abstract: The present invention relates to PTP-D1, a member of the novel PTP-D subfamily of protein tyrosine phosphatases. The present invention is directed to isolated PTP-D1 protein, nucleic acid constructs encoding for PTP-D1, cells containing the nucleic acid constructs, and methods for production and identification of PTP-D1. Antibodies to PTP-D1 protein and methods for screening molecules which can bind to PTP-D1 protein or inhibit or stimulate the protein-tyrosine phosphatase enzymatic activity of PTP-D1, are also provided.
    Type: Grant
    Filed: May 22, 1995
    Date of Patent: November 3, 1998
    Assignee: Max-Planck-Gesellschaft zur Forderung der Wissenschaften E.V.
    Inventors: Axel Ullrich, Niels Peter Hundahl M.o slashed.ller, Karin Bach M.o slashed.ller